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NeoGenomics Laboratories

1 ARTICLES PUBLISHED IN JoVE

Genetics

Wild-type Blocking PCR Combined with Direct Sequencing as a Highly Sensitive Method for Detection of Low-Frequency Somatic Mutations

Adam Z. Albitar¹, Wanlong Ma¹, Maher Albitar¹

¹NeoGenomics Laboratories

Wild-type blocking PCR followed by direct sequencing offers a highly sensitive method of detection for low frequency somatic mutations in a variety of sample types.