TVHS VA Medical Center
2 ARTICLES PUBLISHED IN JoVE
Biology
Development of a Cell Co-Culture Model to Mimic Cardiac Ischemia/Reperfusion In Vitro
Zhu Li 1, Matthew J. W. Hampton 1, Matthew B. Barajas 1, Matthias L. Riess 1,2,3
1Department of Anesthesiology, Vanderbilt University Medical Center, 2Anesthesiology, TVHS VA Medical Center, 3Department of Pharmacology, Vanderbilt University
Spatial distance is a key parameter in assessing hypoxia/reoxygenation injury in a co-culture model of separate endothelial and cardiomyocyte cell layers, suggesting, for the first time, that optimizing the co-culture spatial environment is necessary to provide a favorable in vitro model for testing the role of endothelial cells in cardiomyocyte protection.
Current and Novel Experimental Methods in Ischemia/Reperfusion Research: From Cutting-Edge Models to Innovative Therapies
Matthew B. Barajas 1,2, Matthias L. Riess 1,2,3
1Department of Anesthesiology, Vanderbilt University Medical Center, 2Department of Anesthesiology, TVHS VA Medical Center, 3Department of Pharmacology, Vanderbilt University
Current and Novel Experimental Methods in Ischemia/Reperfusion Research: From Cutting-Edge Models to Innovative Therapies
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