Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted ProductsChris J. C. Johnston 1, Elaine Robertson 1, Yvonne Harcus 1, John R. Grainger 2, Gillian Coakley 1, Danielle J. Smyth 1, Henry J. McSorley 1, Rick Maizels 1
1Institute of Immunology and Infection Research, University of Edinburgh, 2Manchester Collaborative Centre for Inflammation Research
Heligmosomoides polygyrus is a murine nematode with powerful immunomodulatory capabilities that closely resemble those of highly-prevalent human helminth infection. Here we describe a protocol for the long-term maintenance of the H. polygyrus lifecycle.
