UCL Institute of Child Health and Great Ormond Street Hospital
2 ARTICLES PUBLISHED IN JoVE
Bioengineering
A Decellularization Methodology for the Production of a Natural Acellular Intestinal Matrix
Panagiotis Maghsoudlou *1, Giorgia Totonelli *1, Stavros P Loukogeorgakis 1, Simon Eaton 1, Paolo De Coppi 1
1Surgery Unit, Institute of Child Health and Great Ormond Street Hospital, University College London
The article describes a methodology for the production of an acellular matrix from rat intestine. The derivation of intestinal scaffolds is important for future applications in tissue engineering, stem cell biology and drug testing.
Developmental Biology
The Production of Pluripotent Stem Cells from Mouse Amniotic Fluid Cells Using a Transposon System
Enrica Bertin 1, Martina Piccoli 1, Chiara Franzin 1, Andras Nagy 2, Maria Mileikovsky 2, Paolo De Coppi 3, Michela Pozzobon 1
1Stem Cell and Regenerative Medicine Laboratory, Fondazione Istituto di Ricerca Pediatrica Citta della Speranza, 2Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 3Stem Cells and Regenerative Medicine Section, Developmental Biology and Cancer Programme, UCL Institute of Child Health and Great Ormond Street Hospital
In this study, we generate induced pluripotent stem cells from mouse amniotic fluid cells, using a non-viral-based transposon system.
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