Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino AcidShaun Pacheco 1, Shan-Yu Fung 2, Mingyao Liu 1,3
1Latner Thoracic Surgery Research Laboratories, University Health Network, 2Department of Pediatrics, British Columbia Children's Hospital & University of British Columbia, 3Institute of Medical Science, University of Toronto
This protocol describes a clinically-applicable means of dissolving hydrophobic compounds in an aqueous environment using combinations of self-assembling peptide and amino acid solutions. Our method resolves a major limitation of hydrophobic therapeutics, which lack safe, efficient means of solubility and delivery methods into clinical settings.
