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Key Laboratory of Acupuncture and Neurology of Zhejiang Province

2 ARTICLES PUBLISHED IN JoVE

Behavior

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

Qimiao Hu^*1, Xiaoli Zheng^*1, Ruixiang Chen¹, Boyu Liu¹, Yan Tai², Xiaomei Shao¹, Jianqiao Fang¹, Boyi Liu¹

¹Department of Neurobiology and Acupuncture Research, The Third Clinical Medical College, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, ²Academy of Chinese Medical Sciences, Zhejiang Chinese Medical University

Provided here is a protocol that details steps to establish an animal model of chronic post-ischemia pain (CPIP). This is a well-recognized model mimicking human complex regional pain syndrome type-I. Mechanical and thermal hypersensitivities are further evaluated, as well as capsaicin-induced nocifensive behaviors observed in the CPIP rat model.

Medicine

Herbs-Partitioned Moxibustion on the Navel in a Rat Model of Primary Dysmenorrhea with Cold Coagulation and Blood Stasis

Wei-wei Xu^*1, Zhi-qing Teng^*1, Quan-qing Wan², Xiao-mei Shao^1,3, Hong-fang Tian²

¹The Third Clinical Medical College of Zhejiang Chinese Medical University, ²The Third Affiliated Hospital of Zhejiang Chinese Medical University, ³Department of Neurobiology and Acupuncture Research, Key Laboratory of Acupuncture and Neurology of Zhejiang Province

Here, we describe in detail the operation procedures and precautions to be taken during herbs-partitioned moxibustion on the navel in the treatment of primary dysmenorrhea in rats with cold coagulation and blood stasis, which can significantly improve the writhing reaction of dysmenorrhea rats and alleviate pain.