Preclinical Drug Testing in Scalable 3D Engineered Muscle TissuesBonnie J. Berry *1, Shawn M. Luttrell *1, Charles T. Moerk 1, Jesse Macadangdang 1, Jessica Perez 1, Kevin Gray 1, Hamed Ghazizadeh 1, Samir Kharoufeh 1, Brandon Nelsen 1, Nicholas A. Geisse 1
1Curi Bio Inc.
This protocol provides methods for generating 3D engineered cardiac and skeletal muscle tissues and describes their use in preclinical drug screening modalities. The described methods utilize a magnetic sensing system to facilitate the simultaneous assessment of 24 tissues in parallel.
