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1 ARTICLES PUBLISHED IN JoVE

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Biology

Procedure for Fabricating Biofunctional Nanofibers
Jereme Doss 1, Omotunde Olubi 1, Biswajit Sannigrahi 1, M. D. Williams 2, Deepti Gadi 3, Barbara Baird 3, Ishrat Khan 1
1Department of Chemistry, Clark Atlanta University, 2Department of Physics, Clark Atlanta University, 3Department of Chemistry and Chemical Biology, Cornell University

An efficient approach for preparing nanofibers decorated with functional groups capable of specifically interacting with proteins is described. The approach first requires the preparation of a polymer functionalized with the appropriate functional group. The functional polymer is fabricated into nanofibers by electrospinning. The effectiveness of the binding of the nanofibers with a protein is studied by confocal microscopy.

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