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Capítulo 9

Traducción: De ARN a proteína

Traducción
Traducción
Lesson: Translation Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following ...
Activación del ARNt
Activación del ARNt
Aminoacyl-tRNA synthetases are present in both eukaryotes and bacteria. Though eukaryotes have 20 different aminoacyl-tRNA synthetases to couple to 20 ...
Ribosomas
Ribosomas
Ribosomes translate genetic information encoded by messenger RNA (mRNA) into proteins. Both prokaryotic and eukaryotic cells have ribosomes. Cells that ...
Mejora de la precisión traslacional
Mejora de la precisión traslacional
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single ...
Inicio de la traducción
Inicio de la traducción
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are ...
Terminación de la traducción
Terminación de la traducción
The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the ...
Desintegración del ARNm mediada por sinsentido
Desintegración del ARNm mediada por sinsentido
The Upf proteins that carry out nonsense-mediated decay (NMD) are found in all eukaryotic organisms, including humans. Each protein has an individual ...
Chaperonas moleculares y plegamiento de proteínas
Chaperonas moleculares y plegamiento de proteínas
The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form ...
El proteasoma
El proteasoma
Eukaryotic cells can degrade proteins through several pathways. One of the most important amongst these is the ubiquitin-proteasome pathway. It helps the ...
Degradación regulada de proteínas
Degradación regulada de proteínas
It is vital to regulate the activity of enzymatic as well as non-enzymatic proteins inside the cell. This can be achieved either through creating a ...
Proteínas: de los genes a la degradación
Proteínas: de los genes a la degradación
Within a biological system, the DNA encodes the RNA, and the nucleotide sequence in the RNA further defines the amino acid sequence in the protein. This ...
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