Un movimiento versátil modelo murino de la sustancia blanca subcortical para el Estudio de la degeneración axonal y la sustancia blanca Neurobiología

Here we present methodology for the production of a focal stroke in murine white matter by local injection of an irreversible endothelial nitric oxide synthase (eNOS) inhibitor (L-Nio). Presented are two stereotactic variations, retrograde neuronal tracing, and fresh tissue labeling and dissection that expand the potential applications of this technique.