Results: Trauma Animals Show High Levels of Freezing and Lower Shock Reactivity Compared to Controls
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This method can help answer key questions in the behavioral neuroscience field, such as how to better understand underlying biological mechanisms of PTSD. The main advantage of this technique is it is robust, reliable, quantitative, and can be per
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Here we describe the detailed methodology required to conduct stress-enhanced fear learning (SEFL) experiments, a preclinical model of post-traumatic stress disorder, in both rats and mice. The model utilizes aspects of Pavlovian fear conditioning and freezing as an index of enhanced fear in rodents.