Lydie Trautmann

+1 Frameshifting as a novel mechanism to generate a cryptic cytotoxic T lymphocyte epitope derived from human interleukin 10.

Dominant TCR V alpha usage by virus and tumor-reactive T cells with wide affinity ranges for their specific antigens.

Direct killing of Epstein-Barr virus (EBV)-infected B cells by CD4 T cells directed against the EBV lytic protein BHRF1.

Selection of T cell clones expressing high-affinity public TCRs within Human cytomegalovirus-specific CD8 T cell responses.

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction.

The duration of exposure to HIV modulates the breadth and the magnitude of HIV-specific memory CD4+ T cells.

[Inhibition of the PD-1 pathway restores the effector function of HIV-specific T cells].

Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.

T-cell exhaustion in HIV infection.

Early interferon therapy for hepatitis C virus infection rescues polyfunctional, long-lived CD8+ memory T cells.

Drug resistance mutations and the cellular immune response: a valuable synergy for the development of novel immune therapies.

Programmed death 1: a critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections.

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.

Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection.

New approaches to design HIV-1 T-cell vaccines.

Solving vaccine mysteries: a systems biology perspective.

Ex vivo measurement of the cytotoxic capacity of human primary antigen-specific CD8 T cells.

Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation.

Foxo3a: an integrator of immune dysfunction during HIV infection.

Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection.

Beyond surface markers with a universal cell secretion assay.