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Toward synthetic transcription activators: recruitment of transcription factors to DNA by a PNA-peptide chimera.
Journal of the American Chemical Society Mar, 2002 | Pubmed ID: 11866581
Magnetic resonance imaging detects a specific peptide-protein binding event.
Journal of the American Chemical Society Apr, 2002 | Pubmed ID: 11929234
Recruitment of a 19S proteasome subcomplex to an activated promoter.
Science (New York, N.Y.) Apr, 2002 | Pubmed ID: 11964484
Development of protein-detecting microarrays and related devices.
Trends in biochemical sciences Jun, 2002 | Pubmed ID: 12069789
Removal of impurities from transcription factor preparations that alter their DNA-binding properties.
Nucleic acids research Aug, 2002 | Pubmed ID: 12177316
Physical association of the APIS complex and general transcription factors.
Biochemical and biophysical research communications Aug, 2002 | Pubmed ID: 12200147
Inhibition of proteolysis and other posttranslational modifications with substrate-targeted inhibitors.
Biopolymers , 2002 | Pubmed ID: 12325163
A nonproteolytic function of the 19S regulatory subunit of the 26S proteasome is required for efficient activated transcription by human RNA polymerase II.
Biochemistry Oct, 2002 | Pubmed ID: 12379122
Microwave-assisted solid-phase synthesis of peptoids.
Organic letters Nov, 2002 | Pubmed ID: 12423085
Protein affinity labeling mediated by genetically encoded peptide tags.
Angewandte Chemie (International ed. in English) Jan, 2002 | Pubmed ID: 12491432
Immobilized peptides as high-affinity capture agents for self-associating proteins.
Chemistry & biology Mar, 2003 | Pubmed ID: 12670539
Mixed-element capture agents: a simple strategy for the construction of synthetic, high-affinity protein capture ligands.
Journal of the American Chemical Society Aug, 2003 | Pubmed ID: 12903996
Transcription activation by a PNA-peptide chimera in a mammalian cell extract.
Chemistry & biology Oct, 2003 | Pubmed ID: 14583257
Isolation of protein ligands from large peptoid libraries.
Journal of the American Chemical Society Nov, 2003 | Pubmed ID: 14611236
Quantum dots as a visual aid for screening bead-bound combinatorial libraries.
Chembiochem : a European journal of chemical biology Nov, 2003 | Pubmed ID: 14613120
Using oxidative crosslinking and proximity labeling to quantitatively characterize protein-protein and protein-Peptide complexes.
Chemistry & biology Nov, 2003 | Pubmed ID: 14652079
Peptides as modulators of enzymes and regulatory proteins.
Methods (San Diego, Calif.) Apr, 2004 | Pubmed ID: 15003603
Photolithographic synthesis of peptoids.
Journal of the American Chemical Society Apr, 2004 | Pubmed ID: 15053581
Physical and functional association of RNA polymerase II and the proteasome.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2004 | Pubmed ID: 15069196
Target identification in chemical genetics: the (often) missing link.
Chemistry & biology May, 2004 | Pubmed ID: 15157870
Toward a general chemical method for rapidly mapping multi-protein complexes.
Journal of proteome research May-Jun, 2004 | Pubmed ID: 15253422
Transformation of low-affinity lead compounds into high-affinity protein capture agents.
Chemistry & biology Aug, 2004 | Pubmed ID: 15324814
Periodate-triggered cross-linking of DOPA-containing peptide-protein complexes.
Journal of the American Chemical Society Sep, 2004 | Pubmed ID: 15366882
Synthetic molecules as antibody replacements.
Accounts of chemical research Sep, 2004 | Pubmed ID: 15379586
The potential of protein-detecting microarrays for clinical diagnostics.
Advances in clinical chemistry , 2004 | Pubmed ID: 15521193
Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy.
Chemical communications (Cambridge, England) Feb, 2005 | Pubmed ID: 15672142
Genomic studies of transcription factor-DNA interactions.
Current opinion in chemical biology Feb, 2005 | Pubmed ID: 15701451
Techniques: Oxidative cross-linking as an emergent tool for the analysis of receptor-mediated signalling events.
Trends in pharmacological sciences Apr, 2005 | Pubmed ID: 15808346
A high-throughput assay for assessing the cell permeability of combinatorial libraries.
Nature biotechnology Jun, 2005 | Pubmed ID: 15908941
A potent transactivation domain mimic with activity in living cells.
Journal of the American Chemical Society Jun, 2005 | Pubmed ID: 15941237
Protein "fingerprinting" in complex mixtures with peptoid microarrays.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2005 | Pubmed ID: 16123137
NMR analyses of the activation of the Arp2/3 complex by neuronal Wiskott-Aldrich syndrome protein.
Biochemistry Nov, 2005 | Pubmed ID: 16285728
The proteasomal ATPase complex is required for stress-induced transcription in yeast.
Nucleic acids research , 2006 | Pubmed ID: 16517940
Widespread, but non-identical, association of proteasomal 19 and 20 S proteins with yeast chromatin.
The Journal of biological chemistry Sep, 2006 | Pubmed ID: 16837462
Optimized protocols for the isolation of specific protein-binding peptides or peptoids from combinatorial libraries displayed on beads.
Molecular bioSystems Jan, 2006 | Pubmed ID: 16880920
Simple reporter gene-based assays for hairpin poly(amide) conjugate permeability and DNA-binding activity in living cells.
Molecular bioSystems Oct, 2005 | Pubmed ID: 16880996
Identification of Gal4 activation domain-binding proteins in the 26S proteasome by periodate-triggered cross-linking.
Molecular bioSystems Dec, 2005 | Pubmed ID: 16881005
Proteolytic turnover of the Gal4 transcription factor is not required for function in vivo.
Nature Aug, 2006 | Pubmed ID: 16929306
Keeping transcriptional activators under control.
Cell Oct, 2006 | Pubmed ID: 17055428
Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine-containing molecules to proteins.
Journal of the American Chemical Society Nov, 2006 | Pubmed ID: 17117875
The role of the proteasomal ATPases and activator monoubiquitylation in regulating Gal4 binding to promoters.
Genes & development Jan, 2007 | Pubmed ID: 17167105
Isolation and characterization of coactivator-binding peptoids from a combinatorial library.
Molecular bioSystems Nov, 2006 | Pubmed ID: 17216038
Introduction to monitoring and manipulating signaling networks.
Molecular bioSystems Dec, 2006 | Pubmed ID: 17216040
Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival.
Molecular bioSystems Dec, 2006 | Pubmed ID: 17216044
Quantitative evaluation of the relative cell permeability of peptoids and peptides.
Journal of the American Chemical Society Feb, 2007 | Pubmed ID: 17283989
A cell-permeable synthetic transcription factor mimic.
Angewandte Chemie (International ed. in English) , 2007 | Pubmed ID: 17351994
A convenient, high-throughput assay for measuring the relative cell permeability of synthetic compounds.
Nature protocols , 2007 | Pubmed ID: 17401333
Design and synthesis of a cell-permeable synthetic transcription factor mimic.
Journal of combinatorial chemistry Jul-Aug, 2007 | Pubmed ID: 17530904
Identification of a peptoid inhibitor of the proteasome 19S regulatory particle.
Journal of the American Chemical Society Jun, 2007 | Pubmed ID: 17536803
Quantitative comparison of the relative cell permeability of cyclic and linear peptides.
Chemistry & biology Jun, 2007 | Pubmed ID: 17584614
Label transfer chemistry for the characterization of protein-protein interactions.
Journal of the American Chemical Society Oct, 2007 | Pubmed ID: 17894490
Dynamics of the hypoxia-inducible factor-1-vascular endothelial growth factor promoter complex.
The Journal of biological chemistry Nov, 2007 | Pubmed ID: 17916562
Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle.
Journal of the American Chemical Society Oct, 2007 | Pubmed ID: 17929816
The neurohormone orexin stimulates hypoxia-inducible factor-1 activity.
Genes & development Nov, 2007 | Pubmed ID: 18006690
Characterization of proteomic and metabolomic responses to dietary factors and supplements.
The Journal of nutrition Dec, 2007 | Pubmed ID: 18029500
A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(II) tris-bipyridyl as an unusually efficient "warhead".
Molecular bioSystems Jan, 2008 | Pubmed ID: 18075676
The detection limit of a Gd3+-based T1 agent is substantially reduced when targeted to a protein microdomain.
Magnetic resonance imaging Jun, 2008 | Pubmed ID: 18234462
Rapid identification of the pharmacophore in a peptoid inhibitor of the proteasome regulatory particle.
Chemical communications (Cambridge, England) Mar, 2008 | Pubmed ID: 18292891
Activation domain-dependent monoubiquitylation of Gal4 protein is essential for promoter binding in vivo.
The Journal of biological chemistry May, 2008 | Pubmed ID: 18326036
Use of peptide analogue diversity library beads for increased depth of proteomic analysis: application to cerebrospinal fluid.
Journal of proteome research May, 2008 | Pubmed ID: 18357977
A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity.
Journal of the American Chemical Society Apr, 2008 | Pubmed ID: 18386897
High-throughput evaluation of relative cell permeability between peptoids and peptides.
Bioorganic & medicinal chemistry Jun, 2008 | Pubmed ID: 18490170
A peptoid antagonist of VEGF receptor 2 recognizes a 'hotspot' in the extracellular domain distinct from the hormone-binding site.
Bioorganic & medicinal chemistry Jun, 2008 | Pubmed ID: 18501615
Physical and functional interactions of monoubiquitylated transactivators with the proteasome.
The Journal of biological chemistry Aug, 2008 | Pubmed ID: 18515799
Biochemistry: Molecular cloaking devices.
Nature Jun, 2008 | Pubmed ID: 18548057
Proteomes take the electrophilic bait.
Nature chemical biology Jul, 2008 | Pubmed ID: 18560426
The pharmacophore of a peptoid VEGF receptor 2 antagonist includes both side chain and main chain residues.
Bioorganic & medicinal chemistry letters Nov, 2008 | Pubmed ID: 18653335
Rise of the machines: Bruce Alberts and the biochemistry of multi-protein complexes.
Molecular bioSystems Nov, 2008 | Pubmed ID: 18931779
Phosphorylation of the Gal4 DNA-binding domain is essential for activator mono-ubiquitylation and efficient promoter occupancy.
Molecular bioSystems Nov, 2008 | Pubmed ID: 18931787
Encoded combinatorial libraries for the construction of cyclic peptoid microarrays.
Chemical communications (Cambridge, England) Nov, 2008 | Pubmed ID: 19009054
Selective toxin sequestrants for the treatment of bacterial infections.
Journal of the American Chemical Society Apr, 2009 | Pubmed ID: 19351156
Rapid identification of improved protein ligands using peptoid microarrays.
Bioorganic & medicinal chemistry letters Jul, 2009 | Pubmed ID: 19380225
Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins.
Neuron May, 2009 | Pubmed ID: 19447090
Peptoids as potential therapeutics.
Current opinion in molecular therapeutics Jun, 2009 | Pubmed ID: 19479663
Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2009 | Pubmed ID: 19535594
Investigation of the relative cellular permeability of DNA-binding pyrrole-imidazole polyamides.
Journal of medicinal chemistry Aug, 2009 | Pubmed ID: 19610652
Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator.promoter complex by the proteasomal ATPases.
The Journal of biological chemistry Dec, 2009 | Pubmed ID: 19846554
The hydrophobic patch of ubiquitin is required to protect transactivator-promoter complexes from destabilization by the proteasomal ATPases.
Nucleic acids research Jan, 2010 | Pubmed ID: 19939937
Isolation of antagonists of antigen-specific autoimmune T cell proliferation.
Chemistry & biology Nov, 2009 | Pubmed ID: 19942136
No Splicing, no dicing: non-proteolytic roles of the ubiquitin-proteasome system in transcription.
The Journal of biological chemistry Jan, 2010 | Pubmed ID: 19955182
Rapid identification of orexin receptor binding ligands using cell-based screening accelerated with magnetic beads.
Molecular bioSystems Jan, 2010 | Pubmed ID: 20024071
Seamless bead to microarray screening: rapid identification of the highest affinity protein ligands from large combinatorial libraries.
Chemistry & biology Jan, 2010 | Pubmed ID: 20142039
Rethinking screening.
Nature chemical biology Mar, 2010 | Pubmed ID: 20154660
Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates.
Nature chemical biology Apr, 2010 | Pubmed ID: 20228793
Chemistry and biology of orexin signaling.
Molecular bioSystems Aug, 2010 | Pubmed ID: 20532299
The interface of chemical biology and the nervous system (related to the NIDA Chemical Genomics Symposium).
Molecular bioSystems Aug, 2010 | Pubmed ID: 20582378
Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation.
Cancer research Aug, 2010 | Pubmed ID: 20663904
GU81, a VEGFR2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine MMTV-PyMT transgenic model of breast cancer.
BMC cancer , 2010 | Pubmed ID: 20673348
Development of antibody surrogates for the treatment of cancers and autoimmune disease.
Current opinion in chemical biology Dec, 2010 | Pubmed ID: 20674470
Synthetic receptors with antibody-like binding affinities.
Current opinion in chemical biology Dec, 2010 | Pubmed ID: 20674471
MRI detection of VEGFR2 in vivo using a low molecular weight peptoid-(Gd)8-dendron for targeting.
Journal of the American Chemical Society Sep, 2010 | Pubmed ID: 20795620
Identification of candidate IgG biomarkers for Alzheimer's disease via combinatorial library screening.
Cell Jan, 2011 | Pubmed ID: 21215375
Protein binding: Antibody surrogates click into place.
Nature chemistry Jun, 2009 | Pubmed ID: 21378844
The rise, fall and reinvention of combinatorial chemistry.
Chemical communications (Cambridge, England) Sep, 2011 | Pubmed ID: 21701754
Peptoid ligands that bind selectively to phosphoproteins.
Bioorganic & medicinal chemistry letters Sep, 2011 | Pubmed ID: 21742492
Acyl hydrazides as peptoid sub-monomers.
Chemical communications (Cambridge, England) Oct, 2011 | Pubmed ID: 21892506
PDZ dimerization brings proteins together.
Chemistry & biology Sep, 2011 | Pubmed ID: 21944744
Expanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington's disease.
Chemistry & biology Sep, 2011 | Pubmed ID: 21944750
A biomimetic polyketide-inspired approach to small-molecule ligand discovery.
Nature chemistry Feb, 2012 | Pubmed ID: 22270625
Incorporation of heterocycles into the backbone of peptoids to generate diverse peptoid-inspired one bead one compound libraries.
ACS combinatorial science Mar, 2012 | Pubmed ID: 22320121
On-Bead Two-Color (OBTC) Cell Screen for Direct Identification of Highly Selective Cell Surface Receptor Ligands.
Current protocols in chemical biology Mar, 2012 | Pubmed ID: 22582145
A Cleavable Scaffold Strategy for the Synthesis of One-Bead One-Compound Cyclic Peptoid Libraries That Can Be Sequenced By Tandem Mass Spectrometry.
Tetrahedron letters May, 2012 | Pubmed ID: 22736872
Rapid development of a potent photo-triggered inhibitor of the serine hydrolase RBBP9.
Chembiochem : a European journal of chemical biology Sep, 2012 | Pubmed ID: 22907802
Submonomer synthesis of a hybrid peptoid-azapeptoid library.
ACS combinatorial science Oct, 2012 | Pubmed ID: 22958123
Synthesis of libraries of peptidomimetic compounds containing a 2-oxopiperazine unit in the main chain.
Organic & biomolecular chemistry Apr, 2013 | Pubmed ID: 23440085
Discovery of peptoid ligands for anti-aquaporin 4 antibodies.
Chemistry & biology Mar, 2013 | Pubmed ID: 23521793
Synthesis and screening of stereochemically diverse combinatorial libraries of peptide tertiary amides.
Chemistry & biology Mar, 2013 | Pubmed ID: 23521794
Decoding split and pool combinatorial libraries with electron-transfer dissociation tandem mass spectrometry.
Journal of the American Society for Mass Spectrometry Jul, 2013 | Pubmed ID: 23636859
Advances in blood-based protein biomarkers for Alzheimer's disease.
Alzheimer's research & therapy , 2013 | Pubmed ID: 23659521
Features of modularly assembled compounds that impart bioactivity against an RNA target.
ACS chemical biology Oct, 2013 | Pubmed ID: 24032410
A jack of all trades to combat drug-resistant Gram-negative bacteria.
Chemistry & biology Oct, 2013 | Pubmed ID: 24210003
A liquid array platform for the multiplexed analysis of synthetic molecule-protein interactions.
ACS chemical biology Feb, 2014 | Pubmed ID: 24245981
Discovery of biomarkers for systemic lupus erythematosus using a library of synthetic autoantigen surrogates.
Journal of immunological methods Jan, 2014 | Pubmed ID: 24269750
Discovery Of An Orexin Receptor Positive Potentiator.
Chemical science (Royal Society of Chemistry : 2010) Jul, 2010 | Pubmed ID: 24409338
Utility of redundant combinatorial libraries in distinguishing high and low quality screening hits.
ACS combinatorial science Jun, 2014 | Pubmed ID: 24749624