Balu K. Chacko

Transduction of NO-bioactivity by the red blood cell in sepsis: novel mechanisms of vasodilation during acute inflammatory disease.

The red blood cell and vascular function in health and disease.

Regulation of vascular function by haemoglobin.

Revealing anti-inflammatory mechanisms of soy isoflavones by flow: modulation of leukocyte-endothelial cell interactions.

Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation.

Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators.

Pentoxifylline attenuation of experimental hepatopulmonary syndrome.

Effects of venous needle turbulence during ex vivo hemodialysis on endothelial morphology and nitric oxide formation.

Anti-inflammatory effects of isoflavones are dependent on flow and human endothelial cell PPARgamma.

Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation.

Modulatory effects of hypercapnia on in vitro and in vivo pulmonary endothelial-neutrophil adhesive responses during inflammation.

Multiple specificity of human serum dextran-binding immunoglobulin: alpha (1-->6)- and beta (1-->3)-linked glucose and alpha (1-->3)-linked galactose in natural glycoconjugates are recognized.

Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ.

Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis.

Endothelial surface N-glycans mediate monocyte adhesion and are targets for anti-inflammatory effects of peroxisome proliferator-activated receptor γ ligands.

Nitric oxide and hypoxia exacerbate alcohol-induced mitochondrial dysfunction in hepatocytes.

Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: The protective role of autophagy.

Role of endothelial N-glycan mannose residues in monocyte recruitment during atherogenesis.

Utilization of fluorescent probes for the quantification and identification of subcellular proteomes and biological processes regulated by lipid peroxidation products.

Controlling radicals in the powerhouse: development of MitoSOD.

Antioxidant functions for the hemoglobin β93 cysteine residue in erythrocytes and in the vascular compartment in vivo.

Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood.

Mitochondrially targeted compounds and their impact on cellular bioenergetics.

Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita(+/Ins2)-derived β-cells.