Farrah Kheradmand

Shedding light on sheddases: role in growth and development.

Signaling through the EGF receptor controls lung morphogenesis in part by regulating MT1-MMP-mediated activation of gelatinase A/MMP2.

Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency.

Gene therapy of mucus hypersecretion in experimental asthma.

Environmental contributions to the allergic asthma epidemic.

A protease-activated pathway underlying Th cell type 2 activation and allergic lung disease.

16. Immunologic lung disease.

Differential requirement for CD18 in T-helper effector homing.

Airway glycoprotein secretion parallels production and predicts airway obstruction in pulmonary allergy.

Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma.

Overlapping and independent contributions of MMP2 and MMP9 to lung allergic inflammatory cell egression through decreased CC chemokines.

Epidermal detachment, desmosomal dissociation, and destabilization of corneodesmosin in Spink5-/- mice.

An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema.

Endogenous attenuation of allergic lung inflammation by syndecan-1.

The future of asthma therapy: integrating clinical and experimental studies.

The role of relaxin in endometrial cancer.

7. Control of allergic airway inflammation through immunomodulation.

Identification of P311 as a potential gene regulating alveolar generation.

Asthma: pathology and pathophysiology.

Proteomic identification of in vivo substrates for matrix metalloproteinases 2 and 9 reveals a mechanism for resolution of inflammation.

Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted.

Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development.

Antielastin autoimmunity in tobacco smoking-induced emphysema.

A new mechanism regulating the initiation of allergic airway inflammation.

A new link to airway obstruction in asthma.

Discovery of novel markers in allergic lung inflammation through proteomic-based technologies.

Developmental control of integrin expression regulates Th2 effector homing.

Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12.

A3 adenosine receptor signaling influences pulmonary inflammation and fibrosis.

At last, an immune organ we can call our own?

Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma.

Toward a comprehensive understanding of allergic lung disease.

Smoking gun: mature dendritic cells in human lung provide clues to chronic obstructive pulmonary disease.

Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema.

Human rhinovirus proteinase 2A induces TH1 and TH2 immunity in patients with chronic obstructive pulmonary disease.

Proinflammatory role for let-7 microRNAS in experimental asthma.

Endogenous matrix metalloproteinases 2 and 9 regulate activation of CD4+ and CD8+ T cells.

Respiratory tract allergic disease and atopy: experimental evidence for a fungal infectious etiology.

Seeking common pathophysiology in asthma, atopy and sinusitis.

Dual protective mechanisms of matrix metalloproteinases 2 and 9 in immune defense against Streptococcus pneumoniae.

Resting energy expenditure and protein turnover are increased in patients with severe chronic obstructive pulmonary disease.

Cross-sectional analysis of the utility of pulmonary function tests in predicting emphysema in ever-smokers.

Proteinases as molecular adjuvants in allergic airway disease.

Necessary and sufficient role for T helper cells to prevent fungal dissemination in allergic lung disease.

ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization.

Glucose and pyruvate metabolism in severe chronic obstructive pulmonary disease.

Cigarette Smoke Induction of Osteopontin (SPP1) Mediates TH17 Inflammation in Human and Experimental Emphysema.

Autoimmunity in chronic obstructive pulmonary disease: clinical and experimental evidence.

Autoreactive T Cells in Human Smokers is Predictive of Clinical Outcome.

Overexpression of methyl-CpG binding protein 2 impairs T(H)1 responses.

Tracheobronchial mycosis in a retrospective case-series study of five status asthmaticus patients.

CD11a polymorphisms regulate TH2 cell homing and TH2-related disease.

IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps.

Cleavage of fibrinogen by proteinases elicits allergic responses through Toll-like receptor 4.

Agonistic induction of PPARγ reverses cigarette smoke-induced emphysema.

Essential role for autophagy in the maintenance of immunological memory against influenza infection.

Airway surface mycosis in chronic TH2-associated airway disease.

Leukotriene A4 hydrolase: the Janus enzyme shows its ugly side in smokers.

Activation of C3a receptor is required in cigarette smoke-mediated emphysema.

Airway fibrinogenolysis and the initiation of allergic inflammation.

Randomized trial of endobronchial ultrasound-guided transbronchial needle aspiration under general anesthesia versus moderate sedation.

Bioactive lipids in emphysema. Decoding fat to reveal COPD phenotypes.

ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis.

Reply: Is Endobronchial Ultrasound Influenced by Sedation Strategy? Comparing Apples to Apples.

Clinical and Immunological Factors in Emphysema Progression. Five-Year Prospective Longitudinal Exacerbation Study of Chronic Obstructive Pulmonary Disease (LES-COPD).

The microRNA miR-22 inhibits the histone deacetylase HDAC4 to promote T(H)17 cell-dependent emphysema.

Nanoparticulate carbon black in cigarette smoke induces DNA cleavage and Th17-mediated emphysema.

Loss of Peripheral Tolerance in Emphysema. Phenotypes, Exacerbations, and Disease Progression.

Long-Acting Beta Agonists Enhance Allergic Airway Disease.

Allergen-encoded signals that control allergic responses.

Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer.

Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages.

The Role of Matrix Metalloproteinases in Development, Repair, and Destruction of the Lungs.

Cigarette Smoke and DNA Cleavage Promote Lung Inflammation and Emphysema.

Cancer Immunotherapy: Historical Perspective of a Clinical Revolution and Emerging Preclinical Animal Models.

Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer.

Th17/Treg immunoregulation and implications in treatment of sulfur mustard gas-induced lung diseases.

Fibrinogen cleavage products and Toll-like receptor 4 promote the generation of programmed cell death 1 ligand 2-positive dendritic cells in allergic asthma.

AIMp1 Potentiates T1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity.

Advances and Evolving Concepts in Allergic Asthma.

Extracellular matrix in lung development, homeostasis and disease.

Matrix remodeling in chronic lung diseases.

Benefits of antifungal therapy in asthma patients with airway mycosis: A retrospective cohort analysis.

Comprehensive immunoproteogenomic analyses of malignant pleural mesothelioma.

IL17A Regulates Tumor Latency and Metastasis in Lung Adeno and Squamous SQ.2b and AD.1 Cancer.

A Fungal Protease Model to Interrogate Allergic Lung Immunity.

Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer.

Lung tissue microbial profile in lung cancer is distinct from emphysema.

Fungi in Mucoobstructive Airway Diseases.

Laryngeal inflammatory response to smoke and vape in a murine model.

Microglia and amyloid precursor protein coordinate control of transient Candida cerebritis with memory deficits.

Cigarette Smoke Induces Intestinal Inflammation via a Th17 Cell-Neutrophil Axis.

Elastin-Specific Autoimmunity in Smokers With Thoracic Aortic Aneurysm and Dissection is Independent of Chronic Obstructive Pulmonary Disease.

Selective cleavage of fibrinogen by diverse proteinases initiates innate allergic and antifungal immunity through CD11b.

Taming Peptides with Peptides: Neutralizing Proline-Glycine-Proline with l-Arginine-Threonine-Arginine to Treat Cigarette Smoke-induced Emphysema.

Cigarette smoke-induced reduction of C1q promotes emphysema.

A Novel Animal Model of Emphysema Induced by Anti-Elastin Autoimmunity.

Airway mycosis in allergic airway disease.

Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine.

Lung Cancer Heterogeneity in Modulation of Th17/IL17A Responses.

Comprehensive T cell repertoire characterization of non-small cell lung cancer.

E-Cigarette or Vaping Product Use-associated Lung Injury: Developing a Research Agenda. An NIH Workshop Report.

Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-2.

Airway Mycosis and the Regulation of Type 2 Immunity.

A global Slc7a7 knockout mouse model demonstrates characteristic phenotypes of human lysinuric protein intolerance.

Reply to Polverino: Cigarette Smoking and COVID-19: A Complex Interaction.