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Division of Chemistry and Environmental Science,
School of Science and the Environment,
Division of Chemistry and Environmental Science, School of Science and the Environment
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First dual aromatase-steroid sulfatase inhibitors.
Journal of medicinal chemistry Jul, 2003 | Pubmed ID: 12852749
First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors.
Biochemistry May, 2005 | Pubmed ID: 15865431
Dual aromatase-steroid sulfatase inhibitors.
Journal of medicinal chemistry Jul, 2007 | Pubmed ID: 17580845
Synthesis of aromatase inhibitors and dual aromatase steroid sulfatase inhibitors by linking an arylsulfamate motif to 4-(4H-1,2,4-triazol-4-ylamino)benzonitrile: SAR, crystal structures, in vitro and in vivo activities.
ChemMedChem Nov, 2008 | Pubmed ID: 18816537
A new therapeutic strategy against hormone-dependent breast cancer: the preclinical development of a dual aromatase and sulfatase inhibitor.
Clinical cancer research : an official journal of the American Association for Cancer Research Oct, 2008 | Pubmed ID: 18927286
The drug discovery portal: a computational platform for identifying drug leads from academia.
Current pharmaceutical design May, 2010 | Pubmed ID: 20222856
Microwave synthesis of cucurbit[n]urils.
Future medicinal chemistry Feb, 2010 | Pubmed ID: 21426190
Synthesis, full chemical characterisation and development of validated methods for the quantification of (±)-4'-methylmethcathinone (mephedrone): a new "legal high".
Journal of pharmaceutical and biomedical analysis Sep, 2011 | Pubmed ID: 21680127
Evaluation of anionic half generation 3.5-6.5 poly(amidoamine) dendrimers as delivery vehicles for the active component of the anticancer drug cisplatin.
Journal of inorganic biochemistry Sep, 2011 | Pubmed ID: 21704583
Structure-activity relationship for the first-in-class clinical steroid sulfatase inhibitor Irosustat (STX64, BN83495).
ChemMedChem Nov, 2011 | Pubmed ID: 21990014
Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate: Concise synthesis of alangiobussinine.
Beilstein journal of organic chemistry , 2011 | Pubmed ID: 22043251
Synthesis, full chemical characterisation and development of validated methods for the quantification of the components found in the evolved "legal high" NRG-2.
Journal of pharmaceutical and biomedical analysis Mar, 2012 | Pubmed ID: 22169465
Triphenylbutanamines: kinesin spindle protein inhibitors with in vivo antitumor activity.
Journal of medicinal chemistry Feb, 2012 | Pubmed ID: 22248262
Doing the methylene shuffle--further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine.
European journal of medicinal chemistry Aug, 2012 | Pubmed ID: 22749640
Combining aspects of the platinum anticancer drugs picoplatin and BBR3464 to synthesize a new family of sterically hindered dinuclear complexes; their synthesis, binding kinetics and cytotoxicity.
Dalton transactions (Cambridge, England : 2003) Oct, 2012 | Pubmed ID: 22886151
Using isotopic fractionation to link precursor to product in the synthesis of (±)-mephedrone: a new tool for combating "legal high" drugs.
Analytical chemistry Oct, 2012 | Pubmed ID: 22954152
Elucidation of the Phase I and Phase II metabolic pathways of (±)-4'-methylmethcathinone (4-MMC) and (±)-4'-(trifluoromethyl)methcathinone (4-TFMMC) in rat liver hepatocytes using LC-MS and LC-MS².
Journal of pharmaceutical and biomedical analysis Jan, 2013 | Pubmed ID: 22985528
A comparison of the chromatographic properties of silica gel and silicon hydride modified silica gels.
Journal of chromatography. A Nov, 2012 | Pubmed ID: 23040975
A validated stability-indicating HPLC method for routine analysis of an injectable lincomycin and spectinomycin formulation.
Scientia pharmaceutica Dec, 2012 | Pubmed ID: 23264944
Forensic electrochemistry: the electroanalytical sensing of Rohypnol® (flunitrazepam) using screen-printed graphite electrodes without recourse for electrode or sample pre-treatment.
The Analyst Oct, 2013 | Pubmed ID: 23971077
Forensic electrochemistry: the electroanalytical sensing of synthetic cathinone-derivatives and their accompanying adulterants in "legal high" products.
The Analyst Jan, 2014 | Pubmed ID: 24287637
Development of gas chromatography-mass spectrometry (GC-MS) and other rapid screening methods for the analysis of 16 'legal high' cathinone derivatives.
Science & justice : journal of the Forensic Science Society Jan, 2014 | Pubmed ID: 24438774
Manchester Metropolitan University
Michael G. Apps1,
Ben W. Johnson2,
Oliver B. Sutcliffe3,
Sarah D. Brown4,
Nial J. Wheate1
1Faculty of Pharmacy, The University of Sydney,
2School of Science and Health, University of Western Sydney,
3Division of Chemistry and Environmental Science, School of Science and the Environment, Manchester Metropolitan University,
4, Nature Publishing Group
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