Philippe Marin

Identification of new proteins in follicular fluid of mature human follicles.

High performance two-dimensional gel electrophoresis using a wetting agent Tergitol NP7.

Synaptic multiprotein complexes associated with 5-HT(2C) receptors: a proteomic approach.

Synergistic Regulation of Cytosolic Ca2+ Concentration by Adenosine and alpha1-Adrenergic Agonists in Mouse Striatal Astrocytes.

Akt mediates the anti-apoptotic effect of NMDA but not that induced by potassium depolarization in cultured cerebellar granule cells.

Proteomic analysis of astrocytic secretion in the mouse. Comparison with the cerebrospinal fluid proteome.

A proteomic approach based on peptide affinity chromatography, 2-dimensional electrophoresis and mass spectrometry to identify multiprotein complexes interacting with membrane-bound receptors.

The 'magic tail' of G protein-coupled receptors: an anchorage for functional protein networks.

The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins.

Molecular and functional characterization of proteins interacting with the C-terminal domains of 5-HT2 receptors: emergence of 5-HT2 "receptosomes".

GPCR interacting proteins (GIP).

New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting.

GPCR-GIP networks: a first step in the discovery of new therapeutic drugs?

Proteomic detection of prostate-specific antigen using a serum fractionation procedure: potential implication for new low-abundance cancer biomarkers detection.

Difference in mass analysis using labeled lysines (DIMAL-K): a new, efficient proteomic quantification method applied to the analysis of astrocytic secretomes.

Co-assembly of two GluR6 kainate receptor splice variants within a functional protein complex.

[Proteomic profiling: the potential of Seldi-Tof for the identification of new cancer biomarkers].

Calpain product of WT-CRMP2 reduces the amount of surface NR2B NMDA receptor subunit.

Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation.

Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stability.

The proteomic analysis of mouse choroid plexus secretome reveals a high protein secretion capacity of choroidal epithelial cells.

PACAP type I receptor transactivation is essential for IGF-1 receptor signalling and antiapoptotic activity in neurons.

[When two molecules involved in the regulation of mood meet: mutual modulation of the serotonin transporter and neuronal NO-synthase].

GPCR-jacking: from a new route in RTK signalling to a new concept in GPCR activation.

Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction.

PICK1 uncoupling from mGluR7a causes absence-like seizures.

Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions.

Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling.

Enhanced detection of CNS cell secretome in plasma protein-depleted cerebrospinal fluid.

Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling.

GPCR interacting proteins (GIPs) in the nervous system: Roles in physiology and pathologies.

Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SOD1 mice and can trigger motoneuron axonal degeneration and cell death.

Disrupting 5-HT(2A) receptor/PDZ protein interactions reduces hyperalgesia and enhances SSRI efficacy in neuropathic pain.

Constitutive activity of serotonin 2C receptors at G protein-independent signaling: modulation by RNA editing and antidepressants.

The melatonergic agonist and clinically active antidepressant, agomelatine, is a neutral antagonist at 5-HT(2C) receptors.

Techniques for studying inverse agonist activity of antidepressants at recombinant nonedited 5-HT(₂C-INI) receptor and native neuronal 5-HT(₂C) receptors.

G protein activation by serotonin type 4 receptor dimers: evidence that turning on two protomers is more efficient.

The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.

Synthesis and evaluation of bidentate ligands designed to interact with PDZ domains.

5-HT receptor-associated protein networks: new targets for drug discovery in psychiatric disorders?

S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: I. A mechanistic characterization.

Motoneurons secrete angiogenin to induce RNA cleavage in astroglia.

Quantitative proteomic analysis reveals protein expression changes in the murine neuronal secretome during apoptosis.

5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.

5-HT4 receptors constitutively promote the non-amyloidogenic pathway of APP cleavage and interact with ADAM10.

[The mTOR pathway: a new target for treating cognitive deficits of schizophrenia?].

Identification of PDZ ligands by docking-based virtual screening for the development of novel analgesic agents.

Shank3-Rich2 interaction regulates AMPA receptor recycling and synaptic long-term potentiation.

Structure-based design of PDZ ligands as inhibitors of 5-HT(2A) receptor/PSD-95 PDZ1 domain interaction possessing anti-hyperalgesic activity.

Angiogenin induces modifications in the astrocyte secretome: relevance to amyotrophic lateral sclerosis.

Disruption of 5-HT2A receptor-PDZ protein interactions alleviates mechanical hypersensitivity in carrageenan-induced inflammation in rats.

Calcineurin interacts with the serotonin transporter C-terminus to modulate its plasma membrane expression and serotonin uptake.

CRMP2 tethers kainate receptor activity to cytoskeleton dynamics during neuronal maturation.

Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer's disease.

Quantitative phosphoproteomics unravels biased phosphorylation of serotonin 2A receptor at Ser280 by hallucinogenic versus nonhallucinogenic agonists.

Cdk5 induces constitutive activation of 5-HT6 receptors to promote neurite growth.

The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism.

Salivary Gland Proteome Analysis Reveals Modulation of Anopheline Unique Proteins in Insensitive Acetylcholinesterase Resistant Anopheles gambiae Mosquitoes.