Department of Pharmacology and Toxicology
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Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function.
Annual review of pharmacology and toxicology , 2002 | Pubmed ID: 11807178
Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy.
The Journal of biological chemistry Sep, 2002 | Pubmed ID: 12140284
Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer.
The Journal of biological chemistry Nov, 2002 | Pubmed ID: 12244098
Biochemical characterization of beta2-adrenergic receptor dimers and oligomers.
Biological chemistry Jan, 2003 | Pubmed ID: 12674505
Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting.
The Journal of biological chemistry Aug, 2004 | Pubmed ID: 15155738
Pharmacologic chaperones as a potential treatment for X-linked nephrogenic diabetes insipidus.
Journal of the American Society of Nephrology : JASN Jan, 2006 | Pubmed ID: 16319185
Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals.
Biological psychiatry Jan, 2007 | Pubmed ID: 16712807
Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2.
Molecular and cellular biology Oct, 2006 | Pubmed ID: 16908539
Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2007 | Pubmed ID: 17251429
Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization.
Nature methods Aug, 2007 | Pubmed ID: 17664941
Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Oct, 2008 | Pubmed ID: 18185498
Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2008 | Pubmed ID: 18347339
Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor.
Molecular pharmacology Sep, 2008 | Pubmed ID: 18524885
Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2008 | Pubmed ID: 18768802
Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter.
Cellular signalling Jan, 2009 | Pubmed ID: 18929645
Noradrenergic control of cortico-striato-thalamic and mesolimbic cross-structural synchrony.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2010 | Pubmed ID: 20445065
The dopamine metabolite 3-methoxytyramine is a neuromodulator.
PloS one , 2010 | Pubmed ID: 20976142
Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2011 | Pubmed ID: 21436042
Functional interaction between trace amine-associated receptor 1 and dopamine D2 receptor.
Molecular pharmacology Sep, 2011 | Pubmed ID: 21670104
Visualizing receptor endocytosis and trafficking.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21870235
Food for thought: the physiological relevance of ghrelin and dopamine D2 receptor heterodimerization in the regulation of appetite.
Neuron Jan, 2012 | Pubmed ID: 22284175
The role of GRK6 in animal models of Parkinson's disease and L-DOPA treatment.
Scientific reports , 2012 | Pubmed ID: 22393477
Methylphenidate and cocaine self-administration produce distinct dopamine terminal alterations.
Addiction biology Mar, 2014 | Pubmed ID: 22458761
Optimizing the Temporal Resolution of Fast-Scan Cyclic Voltammetry.
ACS chemical neuroscience Apr, 2012 | Pubmed ID: 22708011
BRET biosensors to study GPCR biology, pharmacology, and signal transduction.
Frontiers in endocrinology , 2012 | Pubmed ID: 22952466
BRET approaches to characterize dopamine and TAAR1 receptor pharmacology and signaling.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23296781
Measurement of G protein-coupled receptor surface expression.
Journal of receptor and signal transduction research Jun, 2013 | Pubmed ID: 23557016
A novel assay for measurement of membrane-protein surface expression using a β-lactamase.
Traffic (Copenhagen, Denmark) Jul, 2013 | Pubmed ID: 23574269
Methylphenidate amplifies the potency and reinforcing effects of amphetamines by increasing dopamine transporter expression.
Nature communications , 2013 | Pubmed ID: 24193139
D1 dopamine receptor coupling to PLCβ regulates forward locomotion in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2013 | Pubmed ID: 24227722
N-terminal tagging of the dopamine transporter impairs protein expression and trafficking in vivo.
Molecular and cellular neurosciences Jul, 2014 | Pubmed ID: 24886986
Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2014 | Pubmed ID: 24979780