Duane R. Wesemann

Suppressor of cytokine signaling 1 inhibits cytokine induction of CD40 expression in macrophages.

STAT-1 alpha and IFN-gamma as modulators of TNF-alpha signaling in macrophages: regulation and functional implications of the TNF receptor 1:STAT-1 alpha complex.

Molecular regulation of CD40 gene expression in macrophages and microglia.

Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cells.

TRADD interacts with STAT1-alpha and influences interferon-gamma signaling.

Mechanisms promoting translocations in editing and switching peripheral B cells.

Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70.

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks.

The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates.

Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination.

Functional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair.

Reprogramming IgH isotype-switched B cells to functional-grade induced pluripotent stem cells.

53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.

Microbial colonization influences early B-lineage development in the gut lamina propria.