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Molecular Biology and Biochemistry Department
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On the specificity of interaction between the Saccharomyces cerevisiae clamp loader replication factor C and primed DNA templates during DNA replication.
The Journal of biological chemistry Dec, 2002 | Pubmed ID: 12370190
Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA. Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp.
The Journal of biological chemistry Mar, 2003 | Pubmed ID: 12519754
Mismatch recognition-coupled stabilization of Msh2-Msh6 in an ATP-bound state at the initiation of DNA repair.
Biochemistry Jul, 2003 | Pubmed ID: 12820877
Overproduction and analysis of eukaryotic multiprotein complexes in Escherichia coli using a dual-vector strategy.
Analytical biochemistry Aug, 2003 | Pubmed ID: 12842110
Replication factor C clamp loader subunit arrangement within the circular pentamer and its attachment points to proliferating cell nuclear antigen.
The Journal of biological chemistry Dec, 2003 | Pubmed ID: 14530260
Dual functions, clamp opening and primer-template recognition, define a key clamp loader subunit.
Journal of molecular biology Oct, 2004 | Pubmed ID: 15364574
Asymmetric ATP binding and hydrolysis activity of the Thermus aquaticus MutS dimer is key to modulation of its interactions with mismatched DNA.
Biochemistry Oct, 2004 | Pubmed ID: 15476405
Role of a conserved glutamate residue in the Escherichia coli SecA ATPase mechanism.
The Journal of biological chemistry Apr, 2005 | Pubmed ID: 15710614
Contribution of Msh2 and Msh6 subunits to the asymmetric ATPase and DNA mismatch binding activities of Saccharomyces cerevisiae Msh2-Msh6 mismatch repair protein.
DNA repair Feb, 2006 | Pubmed ID: 16214425
The effects of nucleotides on MutS-DNA binding kinetics clarify the role of MutS ATPase activity in mismatch repair.
Journal of molecular biology Mar, 2007 | Pubmed ID: 17207499
TIRF(ing) reveals Msh2-Msh6 surfing on DNA.
Nature structural & molecular biology Dec, 2007 | Pubmed ID: 18059451
Conserved residues in the delta subunit help the E. coli clamp loader, gamma complex, target primer-template DNA for clamp assembly.
Nucleic acids research Jun, 2008 | Pubmed ID: 18424802
Mechanism of MutS searching for DNA mismatches and signaling repair.
The Journal of biological chemistry Dec, 2008 | Pubmed ID: 18854319
Structure of a mutant form of proliferating cell nuclear antigen that blocks translesion DNA synthesis.
Biochemistry Dec, 2008 | Pubmed ID: 19053247
Mechanism of ATP-driven PCNA clamp loading by S. cerevisiae RFC.
Journal of molecular biology May, 2009 | Pubmed ID: 19285992
Mechanism of cadmium-mediated inhibition of Msh2-Msh6 function in DNA mismatch repair.
Biochemistry Oct, 2009 | Pubmed ID: 19320425
Model-based global analysis of heterogeneous experimental data using gfit.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19399438
Saccharomyces cerevisiae Msh2-Msh6 DNA binding kinetics reveal a mechanism of targeting sites for DNA mismatch repair.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2010 | Pubmed ID: 20080735
Human MSH2 (hMSH2) protein controls ATP processing by hMSH2-hMSH6.
The Journal of biological chemistry Nov, 2011 | Pubmed ID: 21937421
Dynamical allosterism in the mechanism of action of DNA mismatch repair protein MutS.
Biophysical journal Oct, 2011 | Pubmed ID: 21961599
A Central Swivel Point in the RFC Clamp Loader Controls PCNA Opening and Loading on DNA.
Journal of molecular biology Feb, 2012 | Pubmed ID: 22197374
ATP Binding and Hydrolysis-Driven Rate-Determining Events in the RFC-Catalyzed PCNA Clamp Loading Reaction.
Journal of molecular biology Feb, 2012 | Pubmed ID: 22197378
Wesleyan University
F. Noah Biro1,
Jie Zhai1,
Christopher W. Doucette1,
Manju M. Hingorani1
1Molecular Biology and Biochemistry Department, Wesleyan University
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