Subhashini Arimilli

Altered function in CD8+ T cells following paramyxovirus infection of the respiratory tract.

A simian virus 5 (SV5) P/V mutant is less cytopathic than wild-type SV5 in human dendritic cells and is a more effective activator of dendritic cell maturation and function.

TLR-4 and -6 agonists reverse apoptosis and promote maturation of simian virus 5-infected human dendritic cells through NFkB-dependent pathways.

Loss of function in virus-specific lung effector T cells is independent of infection.

Engineered expression of the TLR5 ligand flagellin enhances paramyxovirus activation of human dendritic cell function.

Pivotal Advance: Nonfunctional lung effectors exhibit decreased calcium mobilization associated with reduced expression of ORAI1.

IFNgamma-producing, virus-specific CD8+ effector cells acquire the ability to produce IL-10 as a result of entry into the infected lung environment.

Stimulation of human dendritic cells by wild-type and M protein mutant vesicular stomatitis viruses engineered to express bacterial flagellin.

Evaluation of cytotoxicity of different tobacco product preparations.

Complete artificial saliva alters expression of proinflammatory cytokines in human dermal fibroblasts.

Combustible and non-combustible tobacco product preparations differentially regulate human peripheral blood mononuclear cell functions.

Regulation of gene expression by tobacco product preparations in cultured human dermal fibroblasts.