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Institute of Molecular Pathobiochemistry,
Experimental Gene Therapy and Clinical Chemistry,
Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry
Erawan Borkham-Kamphorst has not added Biography.
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Inhibitory effect of soluble PDGF-beta receptor in culture-activated hepatic stellate cells.
Biochemical and biophysical research communications Apr, 2004 | Pubmed ID: 15063779
Dominant-negative soluble PDGF-beta receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis.
Laboratory investigation; a journal of technical methods and pathology Jun, 2004 | Pubmed ID: 15077122
Antisense strategy against PDGF B-chain proves effective in preventing experimental liver fibrogenesis.
Biochemical and biophysical research communications Aug, 2004 | Pubmed ID: 15358192
Cryopreservation of hepatic stellate cells.
Journal of hepatology May, 2006 | Pubmed ID: 16169118
Disruption of intermolecular disulfide bonds in PDGF-BB dimers by N-acetyl-L-cysteine does not prevent PDGF signaling in cultured hepatic stellate cells.
Biochemical and biophysical research communications Dec, 2005 | Pubmed ID: 16289037
The expression of CSRP2 encoding the LIM domain protein CRP2 is mediated by TGF-beta in smooth muscle and hepatic stellate cells.
Biochemical and biophysical research communications Jul, 2006 | Pubmed ID: 16735029
Pro-fibrogenic potential of PDGF-D in liver fibrosis.
Journal of hepatology Jun, 2007 | Pubmed ID: 17397961
Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury.
Laboratory investigation; a journal of technical methods and pathology Oct, 2008 | Pubmed ID: 18663351
BMP-7 as antagonist of organ fibrosis.
Frontiers in bioscience (Landmark edition) , 2009 | Pubmed ID: 19482601
Expression and functional analysis of endoglin in isolated liver cells and its involvement in fibrogenic Smad signalling.
Cellular signalling Apr, 2011 | Pubmed ID: 21146604
Induction of lipocalin-2 expression in acute and chronic experimental liver injury moderated by pro-inflammatory cytokines interleukin-1β through nuclear factor-κB activation.
Liver international : official journal of the International Association for the Study of the Liver May, 2011 | Pubmed ID: 21457438
CCN3/NOV small interfering RNA enhances fibrogenic gene expression in primary hepatic stellate cells and cirrhotic fat storing cell line CFSC.
Journal of cell communication and signaling Mar, 2012 | Pubmed ID: 21748432
Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice.
Hepatology (Baltimore, Md.) May, 2012 | Pubmed ID: 22237831
A novel, dual role of CCN3 in experimental glomerulonephritis: pro-angiogenic and antimesangioproliferative effects.
The American journal of pathology May, 2012 | Pubmed ID: 22538190
Adenoviral CCN3/NOV gene transfer fails to mitigate liver fibrosis in an experimental bile duct ligation model because of hepatocyte apoptosis.
Liver international : official journal of the International Association for the Study of the Liver Oct, 2012 | Pubmed ID: 22698069
Factor VII activating protease (FSAP) exerts anti-inflammatory and anti-fibrotic effects in liver fibrosis in mice and men.
Journal of hepatology Jan, 2013 | Pubmed ID: 22989567
Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes.
Hepatology (Baltimore, Md.) Feb, 2013 | Pubmed ID: 22996399
Platelet-Derived Growth Factor (PDGF)-C Neutralization Reveals Differential Roles of PDGF Receptors in Liver and Kidney Fibrosis.
The American journal of pathology Jan, 2013 | Pubmed ID: 23141925
Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease.
Journal of inflammation (London, England) , 2012 | Pubmed ID: 23192004
Proteomic profiling in Lipocalin 2 deficient mice under normal and inflammatory conditions.
Journal of proteomics Jan, 2013 | Pubmed ID: 23219901
Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis.
Biochimica et biophysica acta May, 2013 | Pubmed ID: 23376114
The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling.
Biochimica et biophysica acta May, 2014 | Pubmed ID: 24487063
Human mesenchymal stem cells towards non-alcoholic steatohepatitis in an immunodeficient mouse model.
Experimental cell research Aug, 2014 | Pubmed ID: 24786317
Lipocalin-2 (LCN2) regulates PLIN5 expression and intracellular lipid droplet formation in the liver.
Biochimica et biophysica acta Oct, 2014 | Pubmed ID: 25086218
Platelet-derived growth factor-D modulates extracellular matrix homeostasis and remodeling through TIMP-1 induction and attenuation of MMP-2 and MMP-9 gelatinase activities.
Biochemical and biophysical research communications Jan, 2015 | Pubmed ID: 25576870
RWTH Aachen University
Carmen G. Tag1,
Sibille Sauer-Lehnen1,
Sabine Weiskirchen1,
Erawan Borkham-Kamphorst1,
René H. Tolba2,
Frank Tacke3,
Ralf Weiskirchen1
1Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry, RWTH Aachen University,
2Institute for Laboratory Animal Science and Experimental Surgery, RWTH Aachen University,
3Department of Medicine III, RWTH Aachen University
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