Ian Sigal

Finite element modeling of optic nerve head biomechanics.

Reconstruction of human optic nerve heads for finite element modeling.

Factors influencing optic nerve head biomechanics.

Predicted extension, compression and shearing of optic nerve head tissues.

Modeling individual-specific human optic nerve head biomechanics. Part II: influence of material properties.

Modeling individual-specific human optic nerve head biomechanics. Part I: IOP-induced deformations and influence of geometry.

Mesh-morphing algorithms for specimen-specific finite element modeling.

Interactions between geometry and mechanical properties on the optic nerve head.

Biomechanics of the optic nerve head.

Deformation of the normal monkey optic nerve head connective tissue after acute IOP elevation within 3-D histomorphometric reconstructions.

Correlation between local stress and strain and lamina cribrosa connective tissue volume fraction in normal monkey eyes.

3D morphometry of the human optic nerve head.

Mesh morphing and response surface analysis: quantifying sensitivity of vertebral mechanical behavior.

Morphing methods to parameterize specimen-specific finite element model geometries.

Dimensions of the human sclera: Thickness measurement and regional changes with axial length.

Changes in the biomechanical response of the optic nerve head in early experimental glaucoma.

A geometric morphometric assessment of the optic cup in glaucoma.

Deformation of the early glaucomatous monkey optic nerve head connective tissue after acute IOP elevation in 3-D histomorphometric reconstructions.

Glaucomatous cupping of the lamina cribrosa: a review of the evidence for active progressive remodeling as a mechanism.

IOP-induced lamina cribrosa displacement and scleral canal expansion: an analysis of factor interactions using parameterized eye-specific models.

Finite element modeling of the human sclera: influence on optic nerve head biomechanics and connections with glaucoma.

Longitudinal change detected by spectral domain optical coherence tomography in the optic nerve head and peripapillary retina in experimental glaucoma.

3D visualization of aqueous humor outflow structures in-situ in humans.

An applet to estimate the IOP-induced stress and strain within the optic nerve head.

Posterior (outward) migration of the lamina cribrosa and early cupping in monkey experimental glaucoma.

IOP-induced lamina cribrosa deformation and scleral canal expansion: independent or related?

Effect of acute intraocular pressure elevation on the monkey optic nerve head as detected by spectral domain optical coherence tomography.

Lamina Cribrosa Thickening in Early Glaucoma Predicted by a Microstructure Motivated Growth and Remodeling Approach.

The optic nerve head as a robust biomechanical system.

Morphometric analysis of aqueous humor outflow structures with spectral-domain optical coherence tomography.

A few good responses: which mechanical effects of IOP on the ONH to study?

Visualization of the conventional outflow pathway in the living human eye.

Human lamina cribrosa insertion and age.

High dynamic range imaging concept-based signal enhancement method reduced the optical coherence tomography measurement variability.

Individual A-scan signal normalization between two spectral domain optical coherence tomography devices.

Signal normalization reduces systematic measurement differences between spectral-domain optical coherence tomography devices.

Automated lamina cribrosa microstructural segmentation in optical coherence tomography scans of healthy and glaucomatous eyes.

In vivo lamina cribrosa micro-architecture in healthy and glaucomatous eyes as assessed by optical coherence tomography.

Eye-specific IOP-induced displacements and deformations of human lamina cribrosa.

IOP elevation reduces Schlemm's canal cross-sectional area.

Characterisation of Schlemm's canal cross-sectional area.

Gold nanorods as a contrast agent for Doppler optical coherence tomography.

Reproducibility of in-vivo OCT measured three-dimensional human lamina cribrosa microarchitecture.

Repeatability of in vivo 3D lamina cribrosa microarchitecture using adaptive optics spectral domain optical coherence tomography.

Translating ocular biomechanics into clinical practice: current state and future prospects.

Recent advances in OCT imaging of the lamina cribrosa.

Magic angle-enhanced MRI of fibrous microstructures in sclera and cornea with and without intraocular pressure loading.

In vivo three-dimensional characterization of the healthy human lamina cribrosa with adaptive optics spectral-domain optical coherence tomography.

Parameters for lithium treatment are critical in its enhancement of fracture-healing in rodents.

In Vivo Evaluation of White Matter Integrity and Anterograde Transport in Visual System After Excitotoxic Retinal Injury With Multimodal MRI and OCT.

Histogram Matching Extends Acceptable Signal Strength Range on Optical Coherence Tomography Images.