Section of Urology,
Department of Surgery,
Section of Urology, Department of Surgery
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Parathyroid hormone bone anabolic action requires Cbfa1/Runx2-dependent signaling.
Molecular endocrinology (Baltimore, Md.) Mar, 2003 | Pubmed ID: 12554794
The selective estrogen receptor modulator trioxifene (LY133314) inhibits metastasis and extends survival in the PAIII rat prostatic carcinoma model.
Cancer research Sep, 2003 | Pubmed ID: 14522935
The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand.
Molecular pharmacology Mar, 2005 | Pubmed ID: 15602004
Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation.
Molecular cell Apr, 2005 | Pubmed ID: 15808510
Estrogen: a mitochondrial energizer that keeps on going.
Molecular pharmacology Oct, 2005 | Pubmed ID: 16051746
Human splicing factor SPF45 (RBM17) confers broad multidrug resistance to anticancer drugs when overexpressed--a phenotype partially reversed by selective estrogen receptor modulators.
Cancer research Aug, 2005 | Pubmed ID: 16061639
Expression of myo-inositol oxygenase in tissues susceptible to diabetic complications.
Biochemical and biophysical research communications Jan, 2006 | Pubmed ID: 16332355
Regulation of bone mass by Wnt signaling.
The Journal of clinical investigation May, 2006 | Pubmed ID: 16670761
Benzopyrans are selective estrogen receptor beta agonists with novel activity in models of benign prostatic hyperplasia.
Journal of medicinal chemistry Oct, 2006 | Pubmed ID: 17034120
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 2: structure-activity relationship studies on the benzopyran scaffold.
Bioorganic & medicinal chemistry letters Jul, 2007 | Pubmed ID: 17485205
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification.
Bioorganic & medicinal chemistry letters Sep, 2007 | Pubmed ID: 17614275
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 4: functionalization of the benzopyran A-ring.
Bioorganic & medicinal chemistry letters Sep, 2007 | Pubmed ID: 17662603
Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Dec, 2007 | Pubmed ID: 17708715
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 5: Combined A- and C-ring structure-activity relationship studies.
Bioorganic & medicinal chemistry letters Oct, 2007 | Pubmed ID: 17804226
Comparison of results from the semiautomated serum bone alkaline phosphatase isoenzyme assay with the periosteal alkaline phosphatase assay for use in rat models.
Veterinary clinical pathology / American Society for Veterinary Clinical Pathology Sep, 2007 | Pubmed ID: 17806079
Selective estrogen receptor modulators: an update on recent clinical findings.
Obstetrical & gynecological survey Mar, 2008 | Pubmed ID: 18279543
Metastatic breast cancer cells colonize and degrade three-dimensional osteoblastic tissue in vitro.
Clinical & experimental metastasis , 2008 | Pubmed ID: 18543066
Regulation of myogenic differentiation by androgens: cross talk between androgen receptor/ beta-catenin and follistatin/transforming growth factor-beta signaling pathways.
Endocrinology Mar, 2009 | Pubmed ID: 18948405
Extended posterior circumferential approach to thoracic and thoracolumbar spine.
Operative Orthopädie und Traumatologie Sep, 2009 | Pubmed ID: 19779687
Osteogenesis in vitro: from pre-osteoblasts to osteocytes: a contribution from the Osteobiology Research Group, The Pennsylvania State University.
In vitro cellular & developmental biology. Animal Jan, 2010 | Pubmed ID: 19826885
Methicillin-resistant Staphylococcus aureus as a cause of lumbar facet joint septic arthritis: a report of two cases.
The Journal of bone and joint surgery. American volume Feb, 2010 | Pubmed ID: 20124076
Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis.
American journal of physiology. Endocrinology and metabolism Aug, 2010 | Pubmed ID: 20484008
Dynamic interaction between breast cancer cells and osteoblastic tissue: comparison of two- and three-dimensional cultures.
Journal of cellular physiology Aug, 2011 | Pubmed ID: 21520067
The use of titanium mesh cages in the reconstruction of anterior column defects in active spinal infections: can we rest the crest?
Asian spine journal Sep, 2011 | Pubmed ID: 21892387
Reduction of dendritic spines and elevation of GABAergic signaling in the brains of mice treated with an estrogen receptor β ligand.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2012 | Pubmed ID: 22307635
Changes in Cytokines of the Bone Microenvironment during Breast Cancer Metastasis.
International journal of breast cancer , 2012 | Pubmed ID: 22315691
Using MKK4's metastasis suppressor function to identify and dissect cancer cell-microenvironment interactions during metastatic colonization.
Cancer metastasis reviews Dec, 2012 | Pubmed ID: 22706843
Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition.
The Journal of clinical investigation Jul, 2012 | Pubmed ID: 22728933
Left second rib exostosis, spinal cord compression and left upper thoracic scoliosis: a rare triad.
Asian spine journal Sep, 2012 | Pubmed ID: 22977702
An engineered human follistatin variant: insights into the pharmacokinetic and pharmocodynamic relationships of a novel molecule with broad therapeutic potential.
The Journal of pharmacology and experimental therapeutics Mar, 2013 | Pubmed ID: 23249626
Chondrosarcoma of the spinous process: a rare presentation.
Asian spine journal Dec, 2012 | Pubmed ID: 23275812
Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitis.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2013 | Pubmed ID: 23401502
Recurrent Echinococcal Infection of the Lumbar Spine: An 11 Year Follow-up.
Asian spine journal Mar, 2013 | Pubmed ID: 23508512
Milky spots promote ovarian cancer metastatic colonization of peritoneal adipose in experimental models.
The American journal of pathology Aug, 2013 | Pubmed ID: 23885715
Macrofinancing efficient remodeling of damaged muscle tissue.
Cell metabolism Aug, 2013 | Pubmed ID: 23931750
Spontaneous resolution of postoperative lumbar pseudomeningoceles: A report of four cases.
Indian journal of orthopaedics Jul, 2013 | Pubmed ID: 23960289
In vitro mimics of bone remodeling and the vicious cycle of cancer in bone.
Journal of cellular physiology Apr, 2014 | Pubmed ID: 24022654
Gorham's Disease of Spine.
Asian spine journal Sep, 2013 | Pubmed ID: 24066223
Administration of saccharin to neonatal mice influences body composition of adult males and reduces body weight of females.
Endocrinology Apr, 2014 | Pubmed ID: 24456165
Sweet taste receptor deficient mice have decreased adiposity and increased bone mass.
PloS one , 2014 | Pubmed ID: 24466105
Lumbosacral transition vertebra: prevalence and its significance.
Asian spine journal Feb, 2014 | Pubmed ID: 24596605
Symptomatic solitary osteochondroma of the subaxial cervical spine in a 52-year-old patient.
Asian spine journal Feb, 2014 | Pubmed ID: 24596611
Follistatin: a novel therapeutic for the improvement of muscle regeneration.
The Journal of pharmacology and experimental therapeutics May, 2014 | Pubmed ID: 24627466
Inhibition of activin A ameliorates skeletal muscle injury and rescues contractile properties by inducing efficient remodeling in female mice.
The American journal of pathology Apr, 2014 | Pubmed ID: 24655377
Bone marrow adipose tissue is an endocrine organ that contributes to increased circulating adiponectin during caloric restriction.
Cell metabolism Aug, 2014 | Pubmed ID: 24998914
Hemophilic pseudotumor of the first lumbar vertebra.
Indian journal of orthopaedics Nov, 2014 | Pubmed ID: 25404776
The Extended Posterior Circumferential Decompression Technique in the Management of Tubercular Spondylitis with and without Paraplegia.
Asian spine journal Dec, 2014 | Pubmed ID: 25558312
Novel therapeutic approach for neurogenic erectile dysfunction: effect of neurotrophic tyrosine kinase receptor type 1 monoclonal antibody.
European urology Apr, 2015 | Pubmed ID: 25847857
Three-Dimensional in Vitro Model to Study Osteobiology and Osteopathology.
Journal of cellular biochemistry Dec, 2015 | Pubmed ID: 26039562
Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis.
Molecular endocrinology (Baltimore, Md.) Sep, 2015 | Pubmed ID: 26244796
Hypovitaminosis D and Other Risk Factors of Femoral Neck Fracture in South Indian Postmenopausal Women: A Pilot Study.
Journal of clinical and diagnostic research : JCDR Jun, 2015 | Pubmed ID: 26266149
Recurrent Lumbar Disc Herniation: Results of Revision Surgery and Assessment of Factors that May Affect the Outcome. A Non-Concurrent Prospective Study.
Asian spine journal Oct, 2015 | Pubmed ID: 26435791
Molecular targets of androgen signaling that characterize skeletal muscle recovery and regeneration.
Nuclear receptor signaling , 2015 | Pubmed ID: 26457071
Venkatesh Krishnan1,
Robert Clark1,
Marina Chekmareva2,
Amy Johnson1,
Sophia George3,
Patricia Shaw4,
Victoria Seewaldt4,5,
Carrie Rinker-Schaeffer1
1Section of Urology, Department of Surgery, The University of Chicago,
2Department of Pathology, Robert Wood Johnson Medical School,
3Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, University Health Network,
4Department of Laboratory Medicine and Pathobiology, Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, University of Toronto, University Health Network,
5Departments of Medicine, Pharmacology, and Cancer Biology, Duke University Medical Center