Larry Unsworth

Poly(carboxybetaine methacrylamide)-modified nanoparticles: a model system for studying the effect of chain chemistry on film properties, adsorbed protein conformation, and clot formation kinetics.

Chemisorption of thiolated poly(ethylene oxide) to gold: surface chain densities measured by ellipsometry and neutron reflectometry.

Protein resistance of surfaces prepared by sorption of end-thiolated poly(ethylene glycol) to gold: effect of surface chain density.

Polyethylene oxide surfaces of variable chain density by chemisorption of PEO-thiol on gold: adsorption of proteins from plasma studied by radiolabelling and immunoblotting.

In situ neutron reflectometry investigation of gold-chemisorbed PEO layers of varying chain density: relationship of layer structure to protein resistance.

Slow release of molecules in self-assembling peptide nanofiber scaffold.

Hyperthermophilic enzymes--stability, activity and implementation strategies for high temperature applications.

Protein-resistant poly(ethylene oxide)-grafted surfaces: chain density-dependent multiple mechanisms of action.

Controlled release of functional proteins through designer self-assembling peptide nanofiber hydrogel scaffold.

Slow and sustained release of active cytokines from self-assembling peptide scaffolds.

Poly-L-lysine-coated albumin nanoparticles: stability, mechanism for increasing in vitro enzymatic resilience, and siRNA release characteristics.

Engineered peptides with enzymatically cleavable domains for controlling the release of model protein drug from "soft" nanoparticles.

Nanostructured, self-assembling peptide K5 blocks TNF-α and PGE₂ production by suppression of the AP-1/p38 pathway.

Plasma protein adsorption to zwitterionic poly (carboxybetaine methacrylate) modified surfaces: chain chemistry and end-group effects on protein adsorption kinetics, adsorbed amounts and immunoblots.

Bioactive glass 45S5 powders: effect of synthesis route and resultant surface chemistry and crystallinity on protein adsorption from human plasma.

BSA Nanoparticles for siRNA Delivery: Coating Effects on Nanoparticle Properties, Plasma Protein Adsorption, and In Vitro siRNA Delivery.

Understanding the effect of secondary structure on molecular interactions of poly-L-lysine with different substrates by SFA.

Toward a mechanistic understanding of ionic self-complementary peptide self-assembly: role of water molecules and ions.

Cleft palate reconstruction using collagen and nanofiber scaffold incorporating bone morphogenetic protein in rats.

Application of isothermal titration calorimetry for characterizing thermodynamic parameters of biomolecular interactions: peptide self-assembly and protein adsorption case studies.

Peptide-based treatment strategies for cataract.

Thermoreversible hydrogels based on triblock copolymers of poly(ethylene glycol) and carboxyl functionalized poly(ε-caprolactone): The effect of carboxyl group substitution on the transition temperature and biocompatibility in plasma.