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Department of Molecular Microbiology and Center for Women's Infectious Disease Research
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Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli.
mBio , 2014 | Pubmed ID: 25352623
Bacterial outer membrane ushers contain distinct targeting and assembly domains for pilus biogenesis.
Journal of bacteriology Nov, 2002 | Pubmed ID: 12399496
Quantitative studies of the binding of the class II PapG adhesin from uropathogenic Escherichia coli to oligosaccharides.
Bioorganic & medicinal chemistry May, 2003 | Pubmed ID: 12713835
Intracellular bacterial communities of uropathogenic Escherichia coli in urinary tract pathogenesis.
Trends in microbiology Sep, 2004 | Pubmed ID: 15337164
Adaptor function of PapF depends on donor strand exchange in P-pilus biogenesis of Escherichia coli.
Journal of bacteriology Jul, 2007 | Pubmed ID: 17496084
Contribution of autolysin and Sortase a during Enterococcus faecalis DNA-dependent biofilm development.
Infection and immunity Sep, 2009 | Pubmed ID: 19528211
A murine model of urinary tract infection.
Nature protocols , 2009 | Pubmed ID: 19644462
Structural homology between the C-terminal domain of the PapC usher and its plug.
Journal of bacteriology Apr, 2010 | Pubmed ID: 20118254
The differential affinity of the usher for chaperone-subunit complexes is required for assembly of complete pili.
Molecular microbiology Apr, 2010 | Pubmed ID: 20199591
A tale of two pili: assembly and function of pili in bacteria.
Trends in microbiology May, 2010 | Pubmed ID: 20378353
Domain activities of PapC usher reveal the mechanism of action of an Escherichia coli molecular machine.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2012 | Pubmed ID: 22645361
Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice.
Antimicrobial agents and chemotherapy Sep, 2012 | Pubmed ID: 22733070
The structure of the PapD-PapGII pilin complex reveals an open and flexible P5 pocket.
Journal of bacteriology Dec, 2012 | Pubmed ID: 23002225
Positively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformation.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2013 | Pubmed ID: 24003161
Escherichia coli biofilms have an organized and complex extracellular matrix structure.
mBio , 2013 | Pubmed ID: 24023384
Molecular basis of usher pore gating in Escherichia coli pilus biogenesis.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2013 | Pubmed ID: 24297893
Dysregulation of Escherichia coli α-hemolysin expression alters the course of acute and persistent urinary tract infection.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2015 | Pubmed ID: 25675528
Washington University School of Medicine
Matt S. Conover1,
Ana L. Flores-Mireles1,
Michael E. Hibbing1,
Karen Dodson1,
Scott J. Hultgren1
1Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine
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