II. Medizinische Klinik
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Basal insulin gene expression significantly improves conventional insulin therapy in type 1 diabetic rats.
Diabetes Jan, 2002 | Pubmed ID: 11756332
Improved insulin sensitivity is associated with restricted intake of dietary glycoxidation products in the db/db mouse.
Diabetes Jul, 2002 | Pubmed ID: 12086936
Adenovirus-mediated expression of glucokinase in the liver as an adjuvant treatment for type 1 diabetes.
Human gene therapy Sep, 2002 | Pubmed ID: 12228011
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction.
Nature May, 2003 | Pubmed ID: 12754525
Inhibition of Foxo1 function is associated with improved fasting glycemia in diabetic mice.
American journal of physiology. Endocrinology and metabolism Oct, 2003 | Pubmed ID: 12783775
Fat depot-specific expression of adiponectin is impaired in Zucker fatty rats.
Metabolism: clinical and experimental Aug, 2003 | Pubmed ID: 12898458
Elevated vascular endothelial growth factor production in islets improves islet graft vascularization.
Diabetes Apr, 2004 | Pubmed ID: 15047611
Foxo1 mediates insulin action on apoC-III and triglyceride metabolism.
The Journal of clinical investigation Nov, 2004 | Pubmed ID: 15546000
Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance.
Diabetes Feb, 2005 | Pubmed ID: 15677494
PPAR{alpha} mediates the hypolipidemic action of fibrates by antagonizing FoxO1.
American journal of physiology. Endocrinology and metabolism Feb, 2007 | Pubmed ID: 16985262
Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism.
Endocrinology Dec, 2006 | Pubmed ID: 16997836
Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the liver.
Journal of lipid research Jul, 2007 | Pubmed ID: 17449907
Exponential enhancement of oncolytic vesicular stomatitis virus potency by vector-mediated suppression of inflammatory responses in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy Jan, 2008 | Pubmed ID: 18071337
rVSV(M Delta 51)-M3 is an effective and safe oncolytic virus for cancer therapy.
Human gene therapy Jun, 2008 | Pubmed ID: 18533893
Inhibition of the IFN-beta response in hepatocellular carcinoma by alternative spliced isoform of IFN regulatory factor-3.
Molecular therapy : the journal of the American Society of Gene Therapy Nov, 2008 | Pubmed ID: 18781139
Synergistic antitumor effects of transarterial viroembolization for multifocal hepatocellular carcinoma in rats.
Hepatology (Baltimore, Md.) Dec, 2008 | Pubmed ID: 19003878
Graft preconditioning with low-dose tacrolimus (FK506) and nitric oxide inhibitor aminoguanidine (AGH) reduces ischemia/reperfusion injury after liver transplantation in the rat.
Archives of pharmacal research Feb, 2009 | Pubmed ID: 19280151
Clinical value and limitations of [11C]-methionine PET for detection and localization of suspected parathyroid adenomas.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Sep-Oct, 2009 | Pubmed ID: 19340488
Engineered newcastle disease virus as an improved oncolytic agent against hepatocellular carcinoma.
Molecular therapy : the journal of the American Society of Gene Therapy Feb, 2010 | Pubmed ID: 19809404
Surgeon Yurii Voronoy (1895-1961) - a pioneer in the history of clinical transplantation: in memoriam at the 75th anniversary of the first human kidney transplantation.
Transplant international : official journal of the European Society for Organ Transplantation Dec, 2009 | Pubmed ID: 19874569
Cell cycle progression or translation control is not essential for vesicular stomatitis virus oncolysis of hepatocellular carcinoma.
PloS one , 2010 | Pubmed ID: 20539760
Validation of preclinical multiparametric imaging for prediction of necrosis in hepatocellular carcinoma after embolization.
Journal of hepatology Nov, 2011 | Pubmed ID: 21354233
Free-breathing quantitative dynamic contrast-enhanced magnetic resonance imaging in a rat liver tumor model using dynamic radial T(1) mapping.
Investigative radiology Oct, 2011 | Pubmed ID: 21577121
Replicating viral vectors for cancer therapy: strategies to synergize with host immune responses.
Microbial biotechnology Mar, 2012 | Pubmed ID: 21923638
Posttranslational modification of vesicular stomatitis virus glycoprotein, but not JNK inhibition, is the antiviral mechanism of SP600125.
Journal of virology May, 2012 | Pubmed ID: 22345438
Antifibrotic properties of transarterial oncolytic VSV therapy for hepatocellular carcinoma in rats with thioacetamide-induced liver fibrosis.
Molecular therapy : the journal of the American Society of Gene Therapy Nov, 2013 | Pubmed ID: 23939023
Sorting Out Pandora's Box: Discerning the Dynamic Roles of Liver Microenvironment in Oncolytic Virus Therapy for Hepatocellular Carcinoma.
Frontiers in oncology , 2014 | Pubmed ID: 24795862
PET imaging of oncolytic VSV expressing the mutant HSV-1 thymidine kinase transgene in a preclinical HCC rat model.
Molecular therapy : the journal of the American Society of Gene Therapy Apr, 2015 | Pubmed ID: 25609160
Characterization of magnetic viral complexes for targeted delivery in oncology.
Theranostics , 2015 | Pubmed ID: 25897333
Model Matters: Differences in Orthotopic Rat Hepatocellular Carcinoma Physiology Determine Therapy Response to Sorafenib.
Clinical cancer research : an official journal of the American Association for Cancer Research Oct, 2015 | Pubmed ID: 25995341
Jennifer Altomonte1,
Kim A. Muñoz-Álvarez2,
Katsunori Shinozaki3,
Christine Baumgartner4,
Georgios Kaissis5,
Rickmer Braren5,
Oliver Ebert1
1II. Medizinische Klinik, Klinikum rechts der Isar der TU München,
2Department of Nuclear Medicine, Klinikum rechts der Isar der TU München,
3Division of Clinical Oncology, Hiroshima Prefectural Hospital,
4Center for Preclinical Research, Klinikum rechts der Isar der TU München,
5Institute for Diagnostic and Interventional Radiology, Klinikum rechts der Isar der TU München