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Molecular and Cellular Biochemistry,
Center for Molecular Neurobiology,
Integrated Biomedical Science Graduate Program,
Comprehensive Cancer Center,
Molecular and Cellular Biochemistry, Center for Molecular Neurobiology
Tsonwin Hai has not added Biography.
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The roles of ATF3 in liver dysfunction and the regulation of phosphoenolpyruvate carboxykinase gene expression.
The Journal of biological chemistry May, 2002 | Pubmed ID: 11916968
An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli.
Nucleic acids research Jun, 2002 | Pubmed ID: 12034827
Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells.
Blood Mar, 2004 | Pubmed ID: 14604972
Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response.
Molecular and cellular biology Feb, 2004 | Pubmed ID: 14729979
Role for activating transcription factor 3 in stress-induced beta-cell apoptosis.
Molecular and cellular biology Jul, 2004 | Pubmed ID: 15199129
Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination.
The EMBO journal Jul, 2005 | Pubmed ID: 15933712
Profiles of growth hormone (GH)-regulated genes reveal time-dependent responses and identify a mechanism for regulation of activating transcription factor 3 by GH.
The Journal of biological chemistry Feb, 2006 | Pubmed ID: 16326703
Activating transcription factor 3, a stress-inducible gene, suppresses Ras-stimulated tumorigenesis.
The Journal of biological chemistry Apr, 2006 | Pubmed ID: 16469745
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.
Nature May, 2006 | Pubmed ID: 16688168
Activating transcription factor 3 (ATF3) represses the expression of CCL4 in murine macrophages.
Molecular immunology Mar, 2007 | Pubmed ID: 16982098
The regulation of ATF3 gene expression by mitogen-activated protein kinases.
The Biochemical journal Jan, 2007 | Pubmed ID: 17014422
The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer.
Cancer research Dec, 2006 | Pubmed ID: 17178897
Heat shock transcription factor 1 opens chromatin structure of interleukin-6 promoter to facilitate binding of an activator or a repressor.
The Journal of biological chemistry Nov, 2007 | Pubmed ID: 17766920
Negative regulation of TLR-signaling pathways by activating transcription factor-3.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2007 | Pubmed ID: 17785797
The repression of IRS2 gene by ATF3, a stress-inducible gene, contributes to pancreatic beta-cell apoptosis.
Diabetes Mar, 2008 | Pubmed ID: 18057093
Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.
Journal of cell science Jul, 2008 | Pubmed ID: 18559892
ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2009 | Pubmed ID: 19164757
Adipocyte CREB promotes insulin resistance in obesity.
Cell metabolism Mar, 2009 | Pubmed ID: 19254572
ATF3 plays a protective role against toxicity by N-terminal fragment of mutant huntingtin in stable PC12 cell line.
Brain research Aug, 2009 | Pubmed ID: 19559011
Heat shock transcription factor 1 inhibits expression of IL-6 through activating transcription factor 3.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2010 | Pubmed ID: 20018623
Activating transcription factor 3 confers protection against ventilator-induced lung injury.
American journal of respiratory and critical care medicine Aug, 2010 | Pubmed ID: 20413626
The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction.
Molecular endocrinology (Baltimore, Md.) Jul, 2010 | Pubmed ID: 20519332
Cisplatin induces cytotoxicity through the mitogen-activated protein kinase pathways and activating transcription factor 3.
Neoplasia (New York, N.Y.) Jul, 2010 | Pubmed ID: 20651982
ATF3, an adaptive-response gene, enhances TGF{beta} signaling and cancer-initiating cell features in breast cancer cells.
Journal of cell science Oct, 2010 | Pubmed ID: 20930144
ATF3, a hub of the cellular adaptive-response network, in the pathogenesis of diseases: is modulation of inflammation a unifying component?
Gene expression , 2010 | Pubmed ID: 21061913
Loss of metallothionein predisposes mice to diethylnitrosamine-induced hepatocarcinogenesis by activating NF-kappaB target genes.
Cancer research Dec, 2010 | Pubmed ID: 21159647
Angiotensin II signaling up-regulates the immediate early transcription factor ATF3 in the left but not the right atrium.
Basic research in cardiology Mar, 2011 | Pubmed ID: 21191795
Immunohistochemical detection of activating transcription factor 3, a hub of the cellular adaptive-response network.
Methods in enzymology , 2011 | Pubmed ID: 21266251
Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3β independent of JNK activation.
PloS one , 2011 | Pubmed ID: 21541314
ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression.
Nature medicine Jan, 2012 | Pubmed ID: 22179317
The Ohio State University
Erik J. Zmuda1,
Catherine A. Powell1,2,
Tsonwin Hai1,2,3
1Molecular and Cellular Biochemistry, Center for Molecular Neurobiology, The Ohio State University,
2Integrated Biomedical Science Graduate Program, The Ohio State University,
3Comprehensive Cancer Center, The Ohio State University
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