Laszlo Nagy

The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12.

Vascular tunnel construction in the treatment of severe brain swelling caused by trauma and SAH. (evidence based on intra-operative blood flow measure).

Vascular tunnel creation to improve the efficacy of decompressive craniotomy in post-traumatic cerebral edema and ischemic stroke.

[Neurologic complications of aortic dissection].

Impacts of climate change on the tree line.

[Unusually located metastatic tumors of the spine--three case reports].

Molecular determinants of the balance between co-repressor and co-activator recruitment to the retinoic acid receptor.

Characterization of diorganotin(IV) complexes with captopril. The first crystallographically authenticated metal complex of this anti-hypertensive agent.

Cost, morbidity, and control of asthma in Hungary: The Hunair Study.

[Biological and chemical properties of alkyl lead derivatives].

Complex formation of vanadium(IV) with 1,3,5-triamino-1,3,5-trideoxy-cis-inositol and related ligands.

Mechanism of the nuclear receptor molecular switch.

[Applications of metal ions and their complexes in medicine I].

Transcriptional regulation of human CYP27 integrates retinoid, peroxisome proliferator-activated receptor, and liver X receptor signaling in macrophages.

Activation of PPARgamma specifies a dendritic cell subtype capable of enhanced induction of iNKT cell expansion.

Protein/lipid interaction in the bacterial photosynthetic reaction center: phosphatidylcholine and phosphatidylglycerol modify the free energy levels of the quinones.

Retinoids potentiate peroxisome proliferator-activated receptor gamma action in differentiation, gene expression, and lipid metabolic processes in developing myeloid cells.

N-2-mercaptopropionylglycine, a scavanger of reactive oxygen species, does not modify the early antiarrhythmic effect of ischaemic preconditioning in anaesthetised dogs.

Synthesis, structural investigations on organotin(IV) chlorin-e6 complexes, their effect on sea urchin embryonic development and induced apoptosis.

Arginine methylation provides epigenetic transcription memory for retinoid-induced differentiation in myeloid cells.

Why most conservation monitoring is, but need not be, a waste of time.

Coagulation factor XIII-A. A flow cytometric intracellular marker in the classification of acute myeloid leukemias.

Genome-wide localization of histone 4 arginine 3 methylation in a differentiation primed myeloid leukemia cell line.

Roles for lipid-activated transcription factors in atherosclerosis.

Accelerated recovery of 5-fluorouracil-damaged bone marrow after rosiglitazone treatment.

Surgical technique to retract the tentorial edge during subtemporal approach: technical note.

[Application of metal ions and their complexes in medicine II. Application of platina complexes in the treatment of tumor].

SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells.

Water dissection technique of Toth for opening neurosurgical cleavage planes.

Self-regulation of neutrophils during phagocytosis is modified after severe tissue injury.

Enthalpy/entropy driven activation of the first interquinone electron transfer in bacterial photosynthetic reaction centers embedded in vesicles of physiologically important phospholipids.

Twenty years of nuclear receptors: Conference on Nuclear Receptors: from Chromatin to Disease.

Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells.

Differentiation of CD1a- and CD1a+ monocyte-derived dendritic cells is biased by lipid environment and PPARgamma.

PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells.

Chip-on-beads: flow-cytometric evaluation of chromatin immunoprecipitation.

Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance.

Stabilization effect of single-walled carbon nanotubes on the functioning of photosynthetic reaction centers.

PPARgamma, a lipid-activated transcription factor as a regulator of dendritic cell function.

Mechanism of quinol oxidation by ferricenium produced by light excitation in reaction centers of photosynthetic bacteria.

PPARgamma in immunity and inflammation: cell types and diseases.

PPARgamma regulates the function of human dendritic cells primarily by altering lipid metabolism.

Ribonucleoprotein-masked nicks at 50-kbp intervals in the eukaryotic genomic DNA.

Monoclonal antibody proteomics: discovery and prevalidation of chronic obstructive pulmonary disease biomarkers in a single step.

Charge stabilization in reaction center protein investigated by optical heterodyne detected transient grating spectroscopy.

Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling.

Functional ABCG1 expression induces apoptosis in macrophages and other cell types.

Nuclear receptor signalling in dendritic cells connects lipids, the genome and immune function.

Transient receptor potential vanilloid-1 signaling as a regulator of human sebocyte biology.

Spectrally silent light induced conformation change in photosynthetic reaction centers.

The many faces of PPARgamma: anti-inflammatory by any means?

Outcomes of adding second hypoglycemic drug after metformin monotherapy failure among type 2 diabetes in Hungary.

Potential Therapeutic Use of PPARgamma-Programed Human Monocyte-Derived Dendritic Cells in Cancer Vaccination Therapy.

Structural basis for the activation of PPARgamma by oxidized fatty acids.

1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype.

Oxysterol signaling links cholesterol metabolism and inflammation via the liver X receptor in macrophages.

Mycobacterium bovis bacillus Calmette-Guérin infection induces TLR2-dependent peroxisome proliferator-activated receptor gamma expression and activation: functions in inflammation, lipid metabolism, and pathogenesis.

Molecular identification of Trichoderma species associated with Pleurotus ostreatus and natural substrates of the oyster mushroom.

The cost effectiveness of a quadrivalent human papillomavirus vaccine (6/11/16/18) in Hungary.

Activation of liver X receptor sensitizes human dendritic cells to inflammatory stimuli.

Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets.

Activation of retinoic acid receptor signaling coordinates lineage commitment of spontaneously differentiating mouse embryonic stem cells in embryoid bodies.

Factor XIII-A is involved in the regulation of gene expression in alternatively activated human macrophages.

[SCHIZOBANK - The Hungarian national schizophrenia biobank and its role in schizophrenia research and in personalized medicine].

The evolution of autodigestion in the mushroom family Psathyrellaceae (Agaricales) inferred from Maximum Likelihood and Bayesian methods.

Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.

Analyses of association between PPAR gamma and EPHX1 polymorphisms and susceptibility to COPD in a Hungarian cohort, a case-control study.

STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells.

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.

Understanding the evolutionary processes of fungal fruiting bodies: correlated evolution and divergence times in the Psathyrellaceae.

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation.

Gene expression profiles in peripheral blood for the diagnosis of autoimmune diseases.

Chronic obstructive pulmonary disease-specific gene expression signatures of alveolar macrophages as well as peripheral blood monocytes overlap and correlate with lung function.

Where is the unseen fungal diversity hidden? A study of Mortierella reveals a large contribution of reference collections to the identification of fungal environmental sequences.

Peroxisome proliferator-activated receptor γ-regulated cathepsin D is required for lipid antigen presentation by dendritic cells.

Association of peroxisome proliferator-activated receptor gamma polymorphisms with inflammatory bowel disease in a Hungarian cohort.

Phylogeny and species delimitation in the genus Coprinellus with special emphasis on the haired species.

Live-cell fluorescence correlation spectroscopy dissects the role of coregulator exchange and chromatin binding in retinoic acid receptor mobility.

Data partitions, Bayesian analysis and phylogeny of the zygomycetous fungal family Mortierellaceae, inferred from nuclear ribosomal DNA sequences.

Carboxypeptidase-M is regulated by lipids and CSFs in macrophages and dendritic cells and expressed selectively in tissue granulomas and foam cells.

Endoscopic third ventriculostomy in hydrocephalus associated with achondroplasia.

The evolution of defense mechanisms correlate with the explosive diversification of autodigesting Coprinellus mushrooms (Agaricales, Fungi).

Ethanol increases phosphate-mediated mineralization and osteoblastic transformation of vascular smooth muscle cells.

Persistence of initial oral antidiabetic treatment in patients with type 2 diabetes mellitus.

The triad of success in personalised medicine: pharmacogenomics, biotechnology and regulatory issues from a Central European perspective.

Peripheral blood gene expression and IgG glycosylation profiles as markers of tocilizumab treatment in rheumatoid arthritis.

No indication of strict host associations in a widespread mycoparasite: grapevine powdery mildew (Erysiphe necator) is attacked by phylogenetically distant Ampelomyces strains in the field.

Recent plant diversity changes on Europe's mountain summits.

Light induced transmembrane proton gradient in artificial lipid vesicles reconstituted with photosynthetic reaction centers.

Nuclear hormone receptors enable macrophages and dendritic cells to sense their lipid environment and shape their immune response.

Nuclear receptor mediated mechanisms of macrophage cholesterol metabolism.

The use of abdominal binders to treat over-shunting headaches.

Burden of acute gastroenteritis among children younger than 5 years of age--a survey among parents in the United Arab Emirates.

The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.

Homology modeling and phylogenetic relationships of catalases of an opportunistic pathogen Rhizopus oryzae.

Light-harvesting bio-nanomaterial using porous silicon and photosynthetic reaction center.

Would eating carrots protect your liver? A new role involving NKT cells for retinoic acid in hepatitis.

Porous silicon/photosynthetic reaction center hybrid nanostructure.

Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages.

Genome sequence of the button mushroom Agaricus bisporus reveals mechanisms governing adaptation to a humic-rich ecological niche.

Phylogenetic analyses of Coprinopsis sections Lanatuli and Atramentarii identify multiple species within morphologically defined taxa.

Re-mind the gap! Insertion - deletion data reveal neglected phylogenetic potential of the nuclear ribosomal internal transcribed spacer (ITS) of fungi.

A versatile method to design stem-loop primer-based quantitative PCR assays for detecting small regulatory RNA molecules.

Iteratively refined guide trees help improving alignment and phylogenetic inference in the mushroom family Bolbitiaceae.

Genome wide mapping reveals PDE4B as an IL-2 induced STAT5 target gene in activated human PBMCs and lymphoid cancer cells.

Pharmacogenetics and pharmacogenomics in rheumatology.

[The place of functional genomics in oncological research].

Arbuscular mycorrhizal fungal communities along a pedo-hydrological gradient in a Central Amazonian terra firme forest.

RDH10, RALDH2, and CRABP2 are required components of PPARγ-directed ATRA synthesis and signaling in human dendritic cells.

Persistence with statin therapy in Hungary.

Hmgb1 can facilitate activation of the matrilin-1 gene promoter by Sox9 and L-Sox5/Sox6 in early steps of chondrogenesis.

Pro-inflammatory cytokines negatively regulate PPARγ mediated gene expression in both human and murine macrophages via multiple mechanisms.

The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology.

Lignin-degrading peroxidases in Polyporales: an evolutionary survey based on 10 sequenced genomes.

EMDS 2012: 26th Meeting of the European Society for Macrophage and Dendritic Cell Biology in Debrecen, Hungary, September 1-3, 2012.

A novel method to predict regulatory regions based on histone mark landscapes in macrophages.

PPARγ-mediated and arachidonic acid-dependent signaling is involved in differentiation and lipid production of human sebocytes.

Tissue LyC6- macrophages are generated in the absence of circulating LyC6- monocytes and Nur77 in a model of muscle regeneration.

Nuclear receptors as regulators of stem cell and cancer stem cell metabolism.

Nuclear hormone receptors are powerful regulators of stem cell maintenance, differentiation, metabolism and function.

Reprogramming of lysosomal gene expression by interleukin-4 and Stat6.

Ligand binding shifts highly mobile retinoid X receptor to the chromatin-bound state in a coactivator-dependent manner, as revealed by single-cell imaging.

Photosynthetic machineries in nano-systems.

Inotropes and inodilators for acute heart failure: sarcomere active drugs in focus.

Highly efficient differentiation of embryonic stem cells into adipocytes by ascorbic acid.

The intriguing complexities of mammalian gene regulation: how to link enhancers to regulated genes. Are we there yet?

Extensive sampling of basidiomycete genomes demonstrates inadequacy of the white-rot/brown-rot paradigm for wood decay fungi.

Causes and pathophysiology of heart failure with preserved ejection fraction.

The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages.

Latent homology and convergent regulatory evolution underlies the repeated emergence of yeasts.

Measuring expression levels of small regulatory RNA molecules from body fluids and formalin-fixed, paraffin-embedded samples.

Spontaneously improving occipitocondylar hyperplasia: a case report.

Mapping the genomic binding sites of the activated retinoid X receptor in murine bone marrow-derived macrophages using chromatin immunoprecipitation sequencing.

PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors.

PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology.

Photosynthetic reaction centers/ITO hybrid nanostructure.

Craniofacial anomalies.

Combination of IgG N-glycomics and corresponding transcriptomics data to identify anti-TNF-α treatment responders in inflammatory diseases.

Phylogenetic relationships and morphological evolution in Lentinus, Polyporellus and Neofavolus, emphasizing southeastern Asian taxa.

Evolution of novel wood decay mechanisms in Agaricales revealed by the genome sequences of Fistulina hepatica and Cylindrobasidium torrendii.

Convergent losses of decay mechanisms and rapid turnover of symbiosis genes in mycorrhizal mutualists.

Structure and binding efficiency relations of QB site inhibitors of photosynthetic reaction centres.

Differentiation of Adipocytes in Monolayer from Mouse Embryonic Stem Cells.

Erratum: PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors.

9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice.

Oral health-related quality of life after prosthetic rehabilitation: a longitudinal study with the OHIP questionnaire.

[Are there cardiovascular adverse effects of inhaled anticholinergics?].

Genomewide effects of peroxisome proliferator-activated receptor gamma in macrophages and dendritic cells--revealing complexity through systems biology.

Thermal Effects and Structural Changes of Photosynthetic Reaction Centers Characterized by Wide Frequency Band Hydrophone: Effects of Carotenoids and Terbutryn.

Molecular identification and antifungal susceptibility of Curvularia australiensis, C. hawaiiensis and C. spicifera isolated from human eye infections.

Hydranencephaly: Considering Prolonged Survival and Treatment by Endoscopic Choroid Plexus Coagulation.

An integrated pan-tropical biomass map using multiple reference datasets.

Image-guided surgery and craniofacial applications: mastering the unseen.

Structural and Functional Hierarchy in Photosynthetic Energy Conversion-from Molecules to Nanostructures.

Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides Insights into the Origins of Lignocellulose Decay Capabilities.

Psathyloma, a new genus in Hymenogastraceae described from New Zealand.

[MMPI-2 profiles in groups of systemic autoimmune disease - rheumatoid arthritis and systemic lupus erythematosus - patients].

ORM-3819 promotes cardiac contractility through Ca(2+) sensitization in combination with selective PDE III inhibition, a novel approach to inotropy.

Familial Aggregation of Chiari Malformation: Presentation, Pedigree, and Review of the Literature.

Highly Dynamic Transcriptional Signature of Distinct Macrophage Subsets during Sterile Inflammation, Resolution, and Tissue Repair.

The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p.

Is the Mouse a Good Model of Human PPARγ-Related Metabolic Diseases?

OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation.

Motif oriented high-resolution analysis of ChIP-seq data reveals the topological order of CTCF and cohesin proteins on DNA.

Macrophage PPARγ, a Lipid Activated Transcription Factor Controls the Growth Factor GDF3 and Skeletal Muscle Regeneration.

Interactions of retinoids with the ABC transporters P-glycoprotein and Breast Cancer Resistance Protein.

Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function.

MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans.

In situ macrophage phenotypic transition is affected by altered cellular composition prior to acute sterile muscle injury.

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages.

RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification.

Retinoid X receptor suppresses a metastasis-promoting transcriptional program in myeloid cells via a ligand-insensitive mechanism.

Titin isoforms are increasingly protected against oxidative modifications in developing rat cardiomyocytes.

Nucleosome stability measured in situ by automated quantitative imaging.

Immunity meets metabolism and then they start talking.

Commentaries on Viewpoint: Loopomics: a new functional approach to life.

Dynamic transcriptional control of macrophage miRNA signature via inflammation responsive enhancers revealed using a combination of next generation sequencing-based approaches.

The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages.

The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages.

Liver X Receptor Nuclear Receptors Are Transcriptional Regulators of Dendritic Cell Chemotaxis.

A Pharmacogenetic Approach to the Treatment of Patients With Mutations.

Consumption of conjugated linoleic acid (CLA)-supplemented diet during colitis development ameliorates gut inflammation without causing steatosis in mice.

In vivo GDF3 administration abrogates aging related muscle regeneration delay following acute sterile injury.

Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons.

The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory.

Labelled regulatory elements are pervasive features of the macrophage genome and are dynamically utilized by classical and alternative polarization signals.

Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration.

Gene expression analysis of vascular pathophysiology related to anti-TNF treatment in rheumatoid arthritis.

Publisher Correction: Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration.

Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties.

Signal Integration of IFN-I and IFN-II With TLR4 Involves Sequential Recruitment of STAT1-Complexes and NFκB to Enhance Pro-inflammatory Transcription.

The BACH1-HMOX1 Regulatory Axis Is Indispensable for Proper Macrophage Subtype Specification and Skeletal Muscle Regeneration.

Simultaneous Mapping of Molecular Proximity and Comobility Reveals Agonist-Enhanced Dimerization and DNA Binding of Nuclear Receptors.

Unraveling the Hierarchy of and Factors That Determine the DNA Binding by Peroxisome Proliferator-Activated Receptor γ.

Intracardiac Fibrinolysis and Endothelium Activation Related to Atrial Fibrillation Ablation with Different Techniques.

Myeloid ALX/FPR2 regulates vascularization following tissue injury.

Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with retinoid X receptor.

Motif grammar: The basis of the language of gene expression.

Uninterrupted Dabigatran Administration Provides Greater Inhibition against Intracardiac Activation of Hemostasis as Compared to Vitamin K Antagonists during Cryoballoon Catheter Ablation of Atrial Fibrillation.

The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization.