Department of Ophthalmology,
School of Medicine,
Department of Ophthalmology, School of Medicine
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Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment.
The American journal of pathology Feb, 2002 | Pubmed ID: 11839592
Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth.
Investigative ophthalmology & visual science Mar, 2002 | Pubmed ID: 11867604
Periocular gene transfer of sFlt-1 suppresses ocular neovascularization and vascular endothelial growth factor-induced breakdown of the blood-retinal barrier.
Human gene therapy Jan, 2003 | Pubmed ID: 12614564
Retinal neuroprotection against ischemic injury mediated by intraocular gene transfer of pigment epithelium-derived factor.
Investigative ophthalmology & visual science Oct, 2003 | Pubmed ID: 14507898
Long-term survival in a patient with uveal melanoma and liver metastasis.
Archives of ophthalmology (Chicago, Ill. : 1960) Feb, 2004 | Pubmed ID: 14769612
Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor: implications for ocular angiogenesis.
American journal of ophthalmology Apr, 2004 | Pubmed ID: 15059706
Increased expression of iron-regulating genes in monkey and human glaucoma.
Investigative ophthalmology & visual science May, 2004 | Pubmed ID: 15111596
VEGF selectively induces Down syndrome critical region 1 gene expression in endothelial cells: a mechanism for feedback regulation of angiogenesis?
Biochemical and biophysical research communications Aug, 2004 | Pubmed ID: 15358155
Persistence of fetal vasculature in a patient with Knobloch syndrome: potential role for endostatin in fetal vascular remodeling of the eye.
Ophthalmology Oct, 2004 | Pubmed ID: 15465551
Upregulation of placental growth factor by vascular endothelial growth factor via a post-transcriptional mechanism.
FEBS letters Feb, 2005 | Pubmed ID: 15710418
A system for inducible gene expression in retinal ganglion cells.
Investigative ophthalmology & visual science Aug, 2005 | Pubmed ID: 16043868
Use of topical human amniotic fluid in the treatment of acute ocular alkali injuries in mice.
American journal of ophthalmology Aug, 2006 | Pubmed ID: 16876508
Vascular endothelial growth factor upregulates expression of ADAMTS1 in endothelial cells through protein kinase C signaling.
Investigative ophthalmology & visual science Sep, 2006 | Pubmed ID: 16936124
Tissue factor pathway inhibitor-2 is upregulated by vascular endothelial growth factor and suppresses growth factor-induced proliferation of endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology Dec, 2006 | Pubmed ID: 17023682
Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2007 | Pubmed ID: 17595344
Vascular endothelial growth factor induces MEF2C and MEF2-dependent activity in endothelial cells.
Investigative ophthalmology & visual science Aug, 2008 | Pubmed ID: 18450586
Pigment epithelium-derived factor contributes to insulin resistance in obesity.
Cell metabolism Jul, 2009 | Pubmed ID: 19583952
Antipermeability function of PEDF involves blockade of the MAP kinase/GSK/beta-catenin signaling pathway and uPAR expression.
Investigative ophthalmology & visual science Jun, 2010 | Pubmed ID: 20089873
TNFalpha is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis.
Investigative ophthalmology & visual science Mar, 2011 | Pubmed ID: 21212173
Pigment epithelium-derived factor regulates lipid metabolism via adipose triglyceride lipase.
Diabetes May, 2011 | Pubmed ID: 21464445
Nrf2 has a protective role against neuronal and capillary degeneration in retinal ischemia-reperfusion injury.
Free radical biology & medicine Jul, 2011 | Pubmed ID: 21545836
Sema3A [corrected] resists retinal revascularization.
Blood Jun, 2011 | Pubmed ID: 21636713
Inhibition of pathological retinal angiogenesis by the integrin αvβ3 antagonist tetraiodothyroacetic acid (tetrac).
Experimental eye research Jan, 2012 | Pubmed ID: 22123068
Gene delivery nanoparticles specific for human microvasculature and macrovasculature.
Nanomedicine : nanotechnology, biology, and medicine Oct, 2012 | Pubmed ID: 22306159
MEF2C ablation in endothelial cells reduces retinal vessel loss and suppresses pathologic retinal neovascularization in oxygen-induced retinopathy.
The American journal of pathology Jun, 2012 | Pubmed ID: 22521302
Novel targets against retinal angiogenesis in diabetic retinopathy.
Current diabetes reports Aug, 2012 | Pubmed ID: 22638940
Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo.
Journal of controlled release : official journal of the Controlled Release Society Apr, 2013 | Pubmed ID: 23369761
A novel mechanism for glucocorticoid-induced tightening of endothelial barriers.
Investigative ophthalmology & visual science Jun, 2013 | Pubmed ID: 23759428
Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2013 | Pubmed ID: 23959876
Nrf2 acts cell-autonomously in endothelium to regulate tip cell formation and vascular branching.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2013 | Pubmed ID: 24062466
NRF2 plays a protective role in diabetic retinopathy in mice.
Diabetologia Jan, 2014 | Pubmed ID: 24186494
Deletion of placental growth factor prevents diabetic retinopathy and is associated with Akt activation and HIF1α-VEGF pathway inhibition.
Diabetes Jan, 2015 | Pubmed ID: 25187372
Transcription factor MEF2C suppresses endothelial cell inflammation via regulation of NF-κB and KLF2.
Journal of cellular physiology Jun, 2015 | Pubmed ID: 25474999
Pigment epithelium-derived factor inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids.
Biochimica et biophysica acta Mar, 2015 | Pubmed ID: 25562624
Induction of endothelial RAGE expression in pterygium.
Molecular vision , 2014 | Pubmed ID: 25593504
Neuroprotective role of Nrf2 for retinal ganglion cells in ischemia-reperfusion.
Journal of neurochemistry Apr, 2015 | Pubmed ID: 25683606
Deletion of placental growth factor prevents diabetic retinopathy and is associated with Akt activation and HIF1α-VEGF pathway inhibition. diabetes 2015;64:200-212.
Diabetes Mar, 2015 | Pubmed ID: 25713201
Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2015 | Pubmed ID: 26621751
Monomethyl fumarate promotes Nrf2-dependent neuroprotection in retinal ischemia-reperfusion.
Journal of neuroinflammation , 2015 | Pubmed ID: 26689280
Engineered human vascularized constructs accelerate diabetic wound healing.
Biomaterials Jun, 2016 | Pubmed ID: 27328431