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Department of Microbiology and Immunology
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Thymoquinone from nutraceutical black cumin oil activates Neu4 sialidase in live macrophage, dendritic, and normal and type I sialidosis human fibroblast cells via GPCR Galphai proteins and matrix metalloproteinase-9.
Glycoconjugate journal Apr, 2010 | Pubmed ID: 20213245
Thymoquinone-induced Neu4 sialidase activates NFκB in macrophage cells and pro-inflammatory cytokines in vivo.
Glycoconjugate journal Aug, 2010 | Pubmed ID: 20697956
Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for Toll-like receptor activation and cellular signaling.
The Journal of biological chemistry Oct, 2011 | Pubmed ID: 21873432
Queen's University - Kingston, Ontario
Schammim R. Amith*,1,
Preethi Jayanth*,1,
Trisha Finlay*,1,
Susan Franchuk*,1,
Alanna Gilmour*,1,
Samar Abdulkhalek1,
Myron R. Szewczuk*,1
1Department of Microbiology and Immunology, Queen's University - Kingston, Ontario
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