Sang-Jun Ha

IL-23 induces stronger sustained CTL and Th1 immune responses than IL-12 in hepatitis C virus envelope protein 2 DNA immunization.

IL-12 priming during in vitro antigenic stimulation changes properties of CD8 T cells and increases generation of effector and memory cells.

Enhancement of interleukin-12 gene-based tumor immunotherapy by the reduced secretion of p40 subunit and the combination with farnesyltransferase inhibitor.

Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination.

Enhanced immunogenicity and protective efficacy with the use of interleukin-12-encapsulated microspheres plus AS01B in tuberculosis subunit vaccination.

Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection.

Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections.

IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection.

Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection.

Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection.

PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

Lung cancer in never smokers: change of a mindset in the molecular era.

Mechanism of T cell exhaustion in a chronic environment.

Distinct clinical features and outcomes in never-smokers with nonsmall cell lung cancer who harbor EGFR or KRAS mutations or ALK rearrangement.

4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection.

Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells.

Co-immunization of plasmid DNA encoding IL-12 and IL-18 with Bacillus Calmette-Guérin vaccine against progressive tuberculosis.

Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection.

High EGFR gene copy number and skin rash as predictive markers for EGFR tyrosine kinase inhibitors in patients with advanced squamous cell lung carcinoma.

Mind bomb-1 in dendritic cells is specifically required for Notch-mediated T helper type 2 differentiation.

Activation of IL-6R/JAK1/STAT3 signaling induces de novo resistance to irreversible EGFR inhibitors in non-small cell lung cancer with T790M resistance mutation.

Tumor-infiltrating regulatory T cells delineated by upregulation of PD-1 and inhibitory receptors.

Fibroblast growth factor receptor 1 gene amplification is associated with poor survival and cigarette smoking dosage in patients with resected squamous cell lung cancer.

A phase I trial of gefitinib and nimotuzumab in patients with advanced non-small cell lung cancer (NSCLC).

Recruitment of monocytes/macrophages in different tumor microenvironments.

Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells.

PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells.

The impact of cigarette smoking on the frequency of and qualitative differences in KRAS mutations in Korean patients with lung adenocarcinoma.

Egr2 induced during DC development acts as an intrinsic negative regulator of DC immunogenicity.

Negative regulation of type I IFN expression by OASL1 permits chronic viral infection and CD8⁺ T-cell exhaustion.

Differentiation of antigen-specific T cells with limited functional capacity during Mycobacterium tuberculosis infection.

Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.

Regulatory T cells-an important target for cancer immunotherapy.

Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in mice.

Enhancing T Cell Immune Responses by B Cell-based Therapeutic Vaccine Against Chronic Virus Infection.

Inhibition of IL-17A suppresses enhanced-tumor growth in low dose pre-irradiated tumor beds.

Peptidylarginine deiminase inhibition impairs Toll-like receptor agonist-induced functional maturation of dendritic cells, resulting in the loss of T cell-proliferative capacity: a partial mechanism with therapeutic potential in inflammatory settings.

Discrimination between active and latent tuberculosis based on ratio of antigen-specific to mitogen-induced IP-10 production.

Diagnostic performance of a cytokine and IFN-γ-induced chemokine mRNA assay after Mycobacterium tuberculosis-specific antigen stimulation in whole blood from infected individuals.

Identification of a subnuclear body involved in sequence-specific cytokine RNA processing.

PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8+ T cell immune response via the interaction with PD-L1 expressed on CD8+ T cells.

PD-1: Dual guard for immunopathology.

Altered Biological Potential and Radioresponse of Murine Tumors in Different Microenvironments.

IL-4 Induced Innate CD8+ T Cells Control Persistent Viral Infection.

AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation.

A small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens.

Correction: PD-1 Upregulated on Regulatory T Cells during Chronic Virus Infection Enhances the Suppression of CD8+ T Cell Immune Response via the Interaction with PD-L1 Expressed on CD8+ T Cells.

Generation of Tolerogenic Dendritic Cells and Their Therapeutic Applications.

Effect of IL-4 on the Development and Function of Memory-like CD8 T Cells in the Peripheral Lymphoid Tissues.

Cisplatin induces tolerogenic dendritic cells in response to TLR agonists via the abundant production of IL-10, thereby promoting Th2- and Tr1-biased T-cell immunity.

Cell Type Preference of a Novel Human Derived Cell-Permeable Peptide dNP2 and TAT in Murine Splenic Immune Cells.