Michael K. Cooper

Medulloblastoma growth inhibition by hedgehog pathway blockade.

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened.

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

Hedgehog signaling in the murine melanoma microenvironment.

Reappraisal of the role of the DRD3 gene in essential tremor.

Prevalence of unilateral tremor in autosomal dominant essential tremor.

Positive family history of essential tremor influences the motor phenotype of Parkinson's disease.

Activation of the Hedgehog pathway in pilocytic astrocytomas.

Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development.

Clustering of dystonia in some pedigrees with autosomal dominant essential tremor suggests the existence of a distinct subtype of essential tremor.

Lipid modifications of Sonic hedgehog ligand dictate cellular reception and signal response.

Identification of blood protein biomarkers that aid in the clinical assessment of patients with malignant glioma.

Widespread contribution of Gdf7 lineage to cerebellar cell types and implications for hedgehog-driven medulloblastoma formation.

Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling.

Subgroup-specific structural variation across 1,000 medulloblastoma genomes.

Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics.

Identification of Hedgehog pathway responsive glioblastomas by isocitrate dehydrogenase mutation.

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.