Jake A. Kushner

Pdx1 restores beta cell function in Irs2 knockout mice.

Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation.

Islet-sparing effects of protein tyrosine phosphatase-1b deficiency delays onset of diabetes in IRS2 knockout mice.

Effects of dietary glycaemic index on adiposity, glucose homoeostasis, and plasma lipids in animals.

Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes.

Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells.

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth.

Very slow turnover of beta-cells in aged adult mice.

Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis.

Beta-cell growth: an unusual paradigm of organogenesis that is cyclin D2/Cdk4 dependent.

Effects of autoimmunity and immune therapy on beta-cell turnover in type 1 diabetes.

Autoimmunity and beta cell regeneration in mouse and human type 1 diabetes: the peace is not enough.

Growth and regeneration of adult beta cells does not involve specialized progenitors.

Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival.

Exendin-4 improves reversal of diabetes in NOD mice treated with anti-CD3 monoclonal antibody by enhancing recovery of beta-cells.

Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU.

Beta-cell mass and type 1 diabetes: going, going, gone?

Irs2 inactivation suppresses tumor progression in Pten+/- mice.

Adaptive beta-cell proliferation is severely restricted with advanced age.

Cyclin D2 protein stability is regulated in pancreatic beta-cells.

Insulin-like growth factor 2 and the insulin receptor, but not insulin, regulate fetal hepatic glycogen synthesis.

Ductal origin hypothesis of pancreatic regeneration under attack.

Calcineurin signaling regulates human islet {beta}-cell survival.

Aging induces a distinct gene expression program in mouse islets.

Glucose and inflammation control islet vascular density and beta-cell function in NOD mice: control of islet vasculature and vascular endothelial growth factor by glucose.