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Medicine
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Potent antitumor activity of cabozantinib, a c-MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model.
International journal of cancer Apr, 2015 | Pubmed ID: 25242168
Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer.
PloS one , 2014 | Pubmed ID: 25401499
Combined inhibition of MEK and Aurora A kinase in KRAS/PIK3CA double-mutant colorectal cancer models.
Frontiers in pharmacology , 2015 | Pubmed ID: 26136684
A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer.
International journal of cancer Jan, 2016 | Pubmed ID: 26152787
Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts.
Oncotarget Oct, 2015 | Pubmed ID: 26439693
Aldehyde Dehydrogenase 1B1 as a Modulator of Pancreatic Adenocarcinoma.
Pancreas Jan, 2016 | Pubmed ID: 26566217
The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance.
Oncotarget May, 2016 | Pubmed ID: 27070088
Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer.
Oncotarget Jul, 2016 | Pubmed ID: 27385211
University of Colorado Denver Anschutz Medical Campus
Stacey Bagby1,
Wells A. Messersmith1,
Todd M. Pitts1,
Anna Capasso1,
Marileila Varella-Garcia1,
Peter J. Klauck1,
Jihye Kim1,
Aik-Choon Tan1,
S. Gail Eckhardt1,
John J. Tentler1,
John Arcaroli1
1Medicine, University of Colorado Denver Anschutz Medical Campus
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