Barrie Peck

Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer.

FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer.

FOXM1 confers acquired cisplatin resistance in breast cancer cells.

SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2.

A role for the cancer-associated miR-106b~25 cluster in neuronal stem cells.

Antagonism between FOXO and MYC Regulates Cellular Powerhouse.

Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development.

Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth.

Cholesteryl esters: fueling the fury of prostate cancer.

Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation.

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress.

Lipid desaturation - the next step in targeting lipogenesis in cancer?

Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments.

Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.