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Department of Surgery,
Simon Cancer Center and IUPUI Center for Cachexia Research,
Innovation and Therapy,
Department of Surgery, Simon Cancer Center and IUPUI Center for Cachexia Research, Innovation and Therapy
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IGF-1 is downregulated in experimental cancer cachexia.
American journal of physiology. Regulatory, integrative and comparative physiology Sep, 2006 | Pubmed ID: 16614058
New strategies to overcome cancer cachexia: from molecular mechanisms to the 'Parallel Pathway'.
Asia Pacific journal of clinical nutrition , 2008 | Pubmed ID: 18296386
The cytosolic sialidase Neu2 is degraded by autophagy during myoblast atrophy.
Biochimica et biophysica acta Aug, 2009 | Pubmed ID: 19371771
Are antioxidants useful for treating skeletal muscle atrophy?
Free radical biology & medicine Oct, 2009 | Pubmed ID: 19591922
Muscle atrophy in experimental cancer cachexia: is the IGF-1 signaling pathway involved?
International journal of cancer Oct, 2010 | Pubmed ID: 20039316
Therapeutic potential of proteasome inhibition in Duchenne and Becker muscular dystrophies.
The American journal of pathology Apr, 2010 | Pubmed ID: 20304949
Glutamine prevents myostatin hyperexpression and protein hypercatabolism induced in C2C12 myotubes by tumor necrosis factor-α.
Amino acids Feb, 2011 | Pubmed ID: 20623149
β-hydroxy-β-methylbutyrate (HMB) attenuates muscle and body weight loss in experimental cancer cachexia.
International journal of oncology Mar, 2011 | Pubmed ID: 21184031
Changes in myostatin signaling in non-weight-losing cancer patients.
Annals of surgical oncology Apr, 2012 | Pubmed ID: 21519918
STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia.
PloS one , 2011 | Pubmed ID: 21799891
Inflammation, organomegaly, and muscle wasting despite hyperphagia in a mouse model of burn cachexia.
Journal of cachexia, sarcopenia and muscle Mar, 2012 | Pubmed ID: 22476919
JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia.
American journal of physiology. Endocrinology and metabolism Aug, 2012 | Pubmed ID: 22669242
MuRF-1 and p-GSK3β expression in muscle atrophy of cirrhosis.
Liver international : official journal of the International Association for the Study of the Liver May, 2013 | Pubmed ID: 23432902
Early changes of muscle insulin-like growth factor-1 and myostatin gene expression in gastric cancer patients.
Muscle & nerve Sep, 2013 | Pubmed ID: 23861230
Assessment of muscle mass and strength in mice.
BoneKEy reports , 2015 | Pubmed ID: 26331011
STAT3 in the systemic inflammation of cancer cachexia.
Seminars in cell & developmental biology Jun, 2016 | Pubmed ID: 26860754
Effect of the specific proteasome inhibitor bortezomib on cancer-related muscle wasting.
Journal of cachexia, sarcopenia and muscle Jun, 2016 | Pubmed ID: 27239411
Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs.
Oncotarget Jul, 2016 | Pubmed ID: 27259276
Cancer and Chemotherapy Contribute to Muscle Loss by Activating Common Signaling Pathways.
Frontiers in physiology , 2016 | Pubmed ID: 27807421
Indiana University School of Medicine
Andrea Bonetto1,
Joseph E. Rupert1,
Rafael Barreto1,
Teresa A. Zimmers1
1Department of Surgery, Simon Cancer Center and IUPUI Center for Cachexia Research, Innovation and Therapy, Indiana University School of Medicine
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