Wellman Center for Photomedicine
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Thermal response of human skin epidermis to 595-nm laser irradiation at high incident dosages and long pulse durations in conjunction with cryogen spray cooling: an ex-vivo study.
Lasers in surgery and medicine , 2003 | Pubmed ID: 12866117
Comparison of human skin opto-thermal response to near-infrared and visible laser irradiations: a theoretical investigation.
Physics in medicine and biology Nov, 2004 | Pubmed ID: 15584524
Epidermal and vascular damage analysis of in vivo human skin in response to 595 nm pulsed laser irradiation.
Lasers in surgery and medicine Jul, 2005 | Pubmed ID: 15971245
Laser-induced thermal injury to dermal blood vessels: analysis of wavelength (585 nm vs. 595 nm), cryogen spray cooling, and wound healing effects.
Lasers in surgery and medicine Sep, 2005 | Pubmed ID: 16175632
Fractional photothermolysis for treatment of poikiloderma of civatte.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Feb, 2006 | Pubmed ID: 16442059
Fractional photothermolysis for the treatment of surgical scars: a case report.
Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology Apr, 2006 | Pubmed ID: 16581684
Comparative study of cryogen spray cooling with R-134a and R-404a: implications for laser treatment of dark human skin.
Journal of biomedical optics Jul-Aug, 2006 | Pubmed ID: 16965144
Fractional photothermolysis for the treatment of telangiectatic matting: a case report.
Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology Jun, 2007 | Pubmed ID: 17558760
Low-level laser therapy for zymosan-induced arthritis in rats: Importance of illumination time.
Lasers in surgery and medicine Jul, 2007 | Pubmed ID: 17659584
Fractional resurfacing: a new therapeutic modality for Becker's nevus.
Archives of dermatology Dec, 2007 | Pubmed ID: 18086996
Chitosan acetate bandage as a topical antimicrobial dressing for infected burns.
Antimicrobial agents and chemotherapy Feb, 2009 | Pubmed ID: 19015341
Photodynamic therapy for Acinetobacter baumannii burn infections in mice.
Antimicrobial agents and chemotherapy Sep, 2009 | Pubmed ID: 19564369
Photodynamic therapy for localized infections--state of the art.
Photodiagnosis and photodynamic therapy Sep-Dec, 2009 | Pubmed ID: 19932449
Photodynamic therapy for methicillin-resistant Staphylococcus aureus infection in a mouse skin abrasion model.
Lasers in surgery and medicine Jan, 2010 | Pubmed ID: 20077489
Can surgical site infections be treated by photodynamic therapy?
Photodiagnosis and photodynamic therapy Jun, 2010 | Pubmed ID: 20510311
Antimicrobial photodynamic inactivation and photodynamic therapy for infections.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20552347
Photodynamic inactivation of Acinetobacter baumannii using phenothiazinium dyes: in vitro and in vivo studies.
Lasers in surgery and medicine Jul, 2010 | Pubmed ID: 20583252
Treatment of melasma using fractional photothermolysis: a report of eight cases with long-term follow-up.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Aug, 2010 | Pubmed ID: 20666816
Cationic porphycenes as potential photosensitizers for antimicrobial photodynamic therapy.
Journal of medicinal chemistry Nov, 2010 | Pubmed ID: 20936792
Ultraviolet-C irradiation for prevention of central venous catheter-related infections: an in vitro study.
Photochemistry and photobiology Jan-Feb, 2011 | Pubmed ID: 21073470
Photodynamic therapy with a cationic functionalized fullerene rescues mice from fatal wound infections.
Nanomedicine (London, England) Dec, 2010 | Pubmed ID: 21143031
Ultraviolet-C light for treatment of Candida albicans burn infection in mice.
Photochemistry and photobiology Mar-Apr, 2011 | Pubmed ID: 21208209
Analysis of the bacterial heat shock response to photodynamic therapy-mediated oxidative stress.
Photochemistry and photobiology May-Jun, 2011 | Pubmed ID: 21261628
Antimicrobial photodynamic therapy in the colon: delivering a light punch to the guts?
Photochemistry and photobiology Jul-Aug, 2011 | Pubmed ID: 21418077
Synergistic combination of chitosan acetate with nanoparticle silver as a topical antimicrobial: efficacy against bacterial burn infections.
Antimicrobial agents and chemotherapy Jul, 2011 | Pubmed ID: 21502618
Drug discovery of antimicrobial photosensitizers using animal models.
Current pharmaceutical design , 2011 | Pubmed ID: 21504410
Intraperitoneal photodynamic therapy mediated by a fullerene in a mouse model of abdominal dissemination of colon adenocarcinoma.
Nanomedicine : nanotechnology, biology, and medicine Dec, 2011 | Pubmed ID: 21645643
Animal models of external traumatic wound infections.
Virulence Jul-Aug, 2011 | Pubmed ID: 21701256
Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects.
Expert review of anti-infective therapy Jul, 2011 | Pubmed ID: 21810057
Blue dye and red light, a dynamic combination for prophylaxis and treatment of cutaneous Candida albicans infections in mice.
Antimicrobial agents and chemotherapy Dec, 2011 | Pubmed ID: 21930868
Optimal photosensitizers for photodynamic therapy of infections should kill bacteria but spare neutrophils.
Photochemistry and photobiology Jan-Feb, 2012 | Pubmed ID: 21950417
All you need is light: antimicrobial photoinactivation as an evolving and emerging discovery strategy against infectious disease.
Virulence Nov-Dec, 2011 | Pubmed ID: 21971183
Comparison of therapeutic effects between pulsed and continuous wave 810-nm wavelength laser irradiation for traumatic brain injury in mice.
PloS one , 2011 | Pubmed ID: 22028832
The nuts and bolts of low-level laser (light) therapy.
Annals of biomedical engineering Feb, 2012 | Pubmed ID: 22045511
Photodynamic therapy for infections: clinical applications.
Lasers in surgery and medicine Sep, 2011 | Pubmed ID: 22057503
Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes.
Photochemistry and photobiology May-Jun, 2012 | Pubmed ID: 22242675
Ultraviolet C irradiation: an alternative antimicrobial approach to localized infections?
Expert review of anti-infective therapy Feb, 2012 | Pubmed ID: 22339192
Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform.
Frontiers in microbiology , 2012 | Pubmed ID: 22514547
UVC light prophylaxis for cutaneous wound infections in mice.
Antimicrobial agents and chemotherapy Jul, 2012 | Pubmed ID: 22564833
Photodynamic therapy can induce a protective innate immune response against murine bacterial arthritis via neutrophil accumulation.
PloS one , 2012 | Pubmed ID: 22761911
Blue light for infectious diseases: Propionibacterium acnes, Helicobacter pylori, and beyond?
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy Aug, 2012 | Pubmed ID: 22846406
Chitosan dressing promotes healing in third degree burns in mice: gene expression analysis shows biphasic effects for rapid tissue regeneration and decreased fibrotic signaling.
Journal of biomedical materials research. Part A Feb, 2013 | Pubmed ID: 22847951
Ultraviolet C light for Acinetobacter baumannii wound infections in mice: potential use for battlefield wound decontamination?
The journal of trauma and acute care surgery Sep, 2012 | Pubmed ID: 22929495
Killing bacterial spores with blue light: when innate resistance meets the power of light.
Photochemistry and photobiology Jan-Feb, 2013 | Pubmed ID: 22946878
Shining light on nanotechnology to help repair and regeneration.
Biotechnology advances Sep-Oct, 2013 | Pubmed ID: 22951919
Antimicrobial photodynamic therapy with RLP068 kills methicillin-resistant Staphylococcus aureus and improves wound healing in a mouse model of infected skin abrasion PDT with RLP068/Cl in infected mouse skin abrasion.
Journal of biophotonics Sep, 2013 | Pubmed ID: 22987338
Photoinduced electron-transfer mechanisms for radical-enhanced photodynamic therapy mediated by water-soluble decacationic C70 and C84O2 Fullerene Derivatives.
Nanomedicine : nanotechnology, biology, and medicine May, 2013 | Pubmed ID: 23117043
Photodynamic Therapy for Cancer and for Infections: What Is the Difference?
Israel journal of chemistry Sep, 2012 | Pubmed ID: 23248387
Blue light rescues mice from potentially fatal Pseudomonas aeruginosa burn infection: efficacy, safety, and mechanism of action.
Antimicrobial agents and chemotherapy Mar, 2013 | Pubmed ID: 23262998
Transcranial low-level laser therapy improves neurological performance in traumatic brain injury in mice: effect of treatment repetition regimen.
PloS one , 2013 | Pubmed ID: 23308226
Linezolid and vancomycin decrease the therapeutic effect of methylene blue-photodynamic therapy in a mouse model of MRSA bacterial arthritis.
Photochemistry and photobiology May-Jun, 2013 | Pubmed ID: 23311407
Blue light eliminates community-acquired methicillin-resistant Staphylococcus aureus in infected mouse skin abrasions.
Photomedicine and laser surgery Nov, 2013 | Pubmed ID: 23406384
Effect of red and near-infrared wavelengths on low-level laser (light) therapy-induced healing of partial-thickness dermal abrasion in mice.
Lasers in medical science Jan, 2014 | Pubmed ID: 23619627
Antimicrobial photodynamic therapy with decacationic monoadducts and bisadducts of [70]fullerene: in vitro and in vivo studies.
Nanomedicine (London, England) Feb, 2014 | Pubmed ID: 23738632
Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection.
Expert review of anti-infective therapy Jul, 2013 | Pubmed ID: 23879608
Light based anti-infectives: ultraviolet C irradiation, photodynamic therapy, blue light, and beyond.
Current opinion in pharmacology Oct, 2013 | Pubmed ID: 24060701
Antimicrobial blue light therapy for multidrug-resistant Acinetobacter baumannii infection in a mouse burn model: implications for prophylaxis and treatment of combat-related wound infections.
The Journal of infectious diseases Jun, 2014 | Pubmed ID: 24381206
Ultraviolet Radiation in Wound Care: Sterilization and Stimulation.
Advances in wound care Oct, 2013 | Pubmed ID: 24527357
Potentiation of antimicrobial photodynamic inactivation mediated by a cationic fullerene by added iodide: in vitro and in vivo studies.
Nanomedicine (London, England) Mar, 2015 | Pubmed ID: 25723093
Can nanotechnology potentiate photodynamic therapy?
Nanotechnology reviews Mar, 2012 | Pubmed ID: 26361572
Antimicrobial blue light inactivation of Pseudomonas aeruginosa by photo-excitation of endogenous porphyrins: In vitro and in vivo studies.
Lasers in surgery and medicine Jul, 2016 | Pubmed ID: 26891084
Antimicrobial Blue Light Inactivation of Gram-Negative Pathogens in Biofilms: In Vitro and In Vivo Studies.
The Journal of infectious diseases May, 2016 | Pubmed ID: 26908743
Antimicrobial blue light inactivation of Candida albicans: In vitro and in vivo studies.
Virulence Jul, 2016 | Pubmed ID: 26909654
Optical lens-microneedle array for percutaneous light delivery.
Biomedical optics express Oct, 2016 | Pubmed ID: 27867727
The antimicrobial effect of blue light: What are behind?
Virulence Jan, 2017 | Pubmed ID: 28051916
Antimicrobial Blue Light Therapy for Infectious Keratitis: Ex Vivo and In Vivo Studies.
Investigative ophthalmology & visual science Jan, 2017 | Pubmed ID: 28129422
Yucheng Wang1,2,3,
Olivia D. Harrington1,
Ying Wang1,
Clinton K. Murray4,
Michael R. Hamblin1,
Tianhong Dai1
1Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School,
2Department of Medical Oncology, Beijing Institute of Translational Medicine, Chinese Academy of Sciences,
3, Cancer Center, Aviation General Hospital, Beijing,
4Infectious Disease Service, Brooke Army Medical Center