Department of Medicine
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Cardiac-specific overexpression of GLUT1 prevents the development of heart failure attributable to pressure overload in mice.
Circulation Oct, 2002 | Pubmed ID: 12379584
Influence of gender on the response to hemodynamic overload after myocardial infarction.
American journal of physiology. Heart and circulatory physiology Dec, 2002 | Pubmed ID: 12388328
Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes.
Circulation research Jul, 2003 | Pubmed ID: 12829617
Increased myocardial dysfunction after ischemia-reperfusion in mice lacking glucose-6-phosphate dehydrogenase.
Circulation Feb, 2004 | Pubmed ID: 14757696
Human amyloidogenic light chains directly impair cardiomyocyte function through an increase in cellular oxidant stress.
Circulation research Apr, 2004 | Pubmed ID: 15044325
Mesenchymal stem cells in the infarcted heart.
Coronary artery disease Mar, 2005 | Pubmed ID: 15735401
Bifid liver in a patient with diaphragmatic hernia.
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology Jan-Feb, 2005 | Pubmed ID: 15778526
Differential expression and stability of endogenous nuclear factor E2-related factor 2 (Nrf2) by natural chemopreventive compounds in HepG2 human hepatoma cells.
Journal of biochemistry and molecular biology Mar, 2005 | Pubmed ID: 15826493
Nrf2 Possesses a redox-insensitive nuclear export signal overlapping with the leucine zipper motif.
The Journal of biological chemistry Aug, 2005 | Pubmed ID: 15917227
CD31- but Not CD31+ cardiac side population cells exhibit functional cardiomyogenic differentiation.
Circulation research Jul, 2005 | Pubmed ID: 15947249
Comparison of (-)-epigallocatechin-3-gallate elicited liver and small intestine gene expression profiles between C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice.
Pharmaceutical research Nov, 2005 | Pubmed ID: 16132347
Restoration of cardiac progenitor cells after myocardial infarction by self-proliferation and selective homing of bone marrow-derived stem cells.
Circulation research Nov, 2005 | Pubmed ID: 16269652
Modulation of nuclear factor E2-related factor 2-mediated gene expression in mice liver and small intestine by cancer chemopreventive agent curcumin.
Molecular cancer therapeutics Jan, 2006 | Pubmed ID: 16432161
Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice.
Cancer letters Nov, 2006 | Pubmed ID: 16516379
Systematic identification of human mitochondrial disease genes through integrative genomics.
Nature genetics May, 2006 | Pubmed ID: 16582907
Regulation of Nrf2 transactivation domain activity by p160 RAC3/SRC3 and other nuclear co-regulators.
Journal of biochemistry and molecular biology May, 2006 | Pubmed ID: 16756760
Identification of Nrf2-regulated genes induced by chemopreventive isothiocyanate PEITC by oligonucleotide microarray.
Life sciences Oct, 2006 | Pubmed ID: 16828809
Pharmacogenomics of phenolic antioxidant butylated hydroxyanisole (BHA) in the small intestine and liver of Nrf2 knockout and C57BL/6J mice.
Pharmaceutical research Nov, 2006 | Pubmed ID: 16969697
Toxicogenomics of endoplasmic reticulum stress inducer tunicamycin in the small intestine and liver of Nrf2 knockout and C57BL/6J mice.
Toxicology letters Jan, 2007 | Pubmed ID: 17127020
Unveiling gender differences in demand ischemia: a study in a rat model of genetic hypertension.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery Feb, 2007 | Pubmed ID: 17175162
Cell therapy in heart failure.
Heart failure clinics Jul, 2005 | Pubmed ID: 17386854
Adult stem cells and heart regeneration.
Expert review of cardiovascular therapy May, 2007 | Pubmed ID: 17489674
Post-translational modifications in the rat lumbar spinal cord in experimental autoimmune encephalomyelitis.
Journal of proteome research Jul, 2007 | Pubmed ID: 17567059
The bone marrow--cardiac axis of myocardial regeneration.
Progress in cardiovascular diseases Jul-Aug, 2007 | Pubmed ID: 17631435
Long-term effects of increased glucose entry on mouse hearts during normal aging and ischemic stress.
Circulation Aug, 2007 | Pubmed ID: 17679614
Glucosamine prevents in vitro collagen degradation in chondrocytes by inhibiting advanced lipoxidation reactions and protein oxidation.
Arthritis research & therapy , 2007 | Pubmed ID: 17686167
Narrowing in on a diagnosis.
The American journal of medicine Sep, 2007 | Pubmed ID: 17765047
Pharmacogenomic profile of soy isoflavone concentrate in the prostate of Nrf2 deficient and wild-type mice.
Journal of pharmaceutical sciences Oct, 2008 | Pubmed ID: 18236473
Isolation, culture, and functional analysis of adult mouse cardiomyocytes.
Methods in molecular medicine , 2007 | Pubmed ID: 18287677
Myelin lipid abnormalities in the aspartoacylase-deficient tremor rat.
Neurochemical research Jan, 2009 | Pubmed ID: 18478328
Giant benign schwannoma on scalp causing 'double-head'.
Acta neurologica Taiwanica Mar, 2008 | Pubmed ID: 18564825
Quantitative Proteomic Analysis of Formalin Fixed Paraffin Embedded Oral HPV Lesions from HIV Patients.
The open proteomics journal , 2008 | Pubmed ID: 19081750
Ciliary neurotrophic factor (CNTF) plus soluble CNTF receptor alpha increases cyclooxygenase-2 expression, PGE2 release and interferon-gamma-induced CD40 in murine microglia.
Journal of neuroinflammation Mar, 2009 | Pubmed ID: 19267906
A novel role for tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in the development of cardiac dysfunction and failure.
Circulation Apr, 2009 | Pubmed ID: 19349318
Amyotrophic lateral sclerosis: Protein chaperone dysfunction revealed by proteomic studies of animal models.
Proteomics. Clinical applications May, 2008 | Pubmed ID: 19578526
Altered proteolytic events in experimental autoimmune encephalomyelitis discovered by iTRAQ shotgun proteomics analysis of spinal cord.
Proteome science Jul, 2009 | Pubmed ID: 19607715
Aberrant regulation of choline metabolism by mitochondrial electron transport system inhibition in neuroblastoma cells.
Metabolomics : Official journal of the Metabolomic Society Dec, 2008 | Pubmed ID: 19774105
Glutathione peroxidase deficiency exacerbates ischemia-reperfusion injury in male but not female myocardium: insights into antioxidant compensatory mechanisms.
American journal of physiology. Heart and circulatory physiology Dec, 2009 | Pubmed ID: 19801492
Human tail with spina bifida.
British journal of neurosurgery Dec, 2009 | Pubmed ID: 19922280
Redox regulatory mechanism of transnitrosylation by thioredoxin.
Molecular & cellular proteomics : MCP Oct, 2010 | Pubmed ID: 20660346
Profiling the Aspergillus fumigatus proteome in response to caspofungin.
Antimicrobial agents and chemotherapy Jan, 2011 | Pubmed ID: 20974863
In vivo space radiation-induced non-targeted responses: late effects on molecular signaling in mitochondria.
Current molecular pharmacology Jun, 2011 | Pubmed ID: 21166651
Deep anterior lamellar keratoplasty with phacoemulsification.
Journal of cataract and refractive surgery Jan, 2011 | Pubmed ID: 21183107
Echocardiographic speckle-tracking based strain imaging for rapid cardiovascular phenotyping in mice.
Circulation research Apr, 2011 | Pubmed ID: 21372284
Thioredoxin 1-mediated post-translational modifications: reduction, transnitrosylation, denitrosylation, and related proteomics methodologies.
Antioxidants & redox signaling Nov, 2011 | Pubmed ID: 21453190
Distinction of thioredoxin transnitrosylation and denitrosylation target proteins by the ICAT quantitative approach.
Journal of proteomics Oct, 2011 | Pubmed ID: 21704743
The proteomic signature of Aspergillus fumigatus during early development.
Molecular & cellular proteomics : MCP Nov, 2011 | Pubmed ID: 21825280
Proteomic identification of novel targets regulated by the mammalian target of rapamycin pathway during oligodendrocyte differentiation.
Glia Nov, 2011 | Pubmed ID: 21858874
85% of maximal age-predicted heart rate is not a valid endpoint for exercise treadmill testing.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology Dec, 2011 | Pubmed ID: 21922347
Clinical and hemodynamic effects of renin-angiotensin system blockade in cardiac transplant recipients.
The American journal of cardiology Dec, 2011 | Pubmed ID: 22133132
Proteomic identification of immunoproteasome accumulation in formalin-fixed rodent spinal cords with experimental autoimmune encephalomyelitis.
Journal of proteome research Mar, 2012 | Pubmed ID: 22188123
Externalized glycolytic enzymes are novel, conserved, and early biomarkers of apoptosis.
The Journal of biological chemistry Mar, 2012 | Pubmed ID: 22262862
Commentary.
Clinical chemistry May, 2012 | Pubmed ID: 22544857
Cardiac side population cells: moving toward the center stage in cardiac regeneration.
Circulation research May, 2012 | Pubmed ID: 22581921
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation.
Science (New York, N.Y.) May, 2012 | Pubmed ID: 22628656
Topical autologous platelet-rich plasma eyedrops for acute corneal chemical injury.
Cornea Sep, 2012 | Pubmed ID: 22759830
Purkinje cell dysfunction and delayed death in plasma membrane calcium ATPase 2-heterozygous mice.
Molecular and cellular neurosciences Aug, 2012 | Pubmed ID: 22789621
Safety and efficacy of transition from systemic prostanoids to inhaled treprostinil in pulmonary arterial hypertension.
The American journal of cardiology Nov, 2012 | Pubmed ID: 22853986
CCL2 affects β-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease.
Neurobiology of aging Apr, 2013 | Pubmed ID: 23040664
Antegrade interlocking nailing versus dynamic compression plating for humeral shaft fractures.
Journal of orthopaedic surgery (Hong Kong) Dec, 2012 | Pubmed ID: 23255631
PGC1α plays a critical role in TWEAK-induced cardiac dysfunction.
PloS one , 2013 | Pubmed ID: 23342071
Design and properties of efficient tRNA:EF-Tu FRET system for studies of ribosomal translation.
Protein engineering, design & selection : PEDS Feb, 2013 | Pubmed ID: 23447652
Aortoatrial fistula.
American journal of respiratory and critical care medicine Mar, 2013 | Pubmed ID: 23457370
A multidimensional approach to an in-depth proteomics analysis of transcriptional regulators in neuroblastoma cells.
Journal of neuroscience methods Apr, 2013 | Pubmed ID: 23558336
An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry.
Nature Jul, 2013 | Pubmed ID: 23792561
Serial evaluation of microcirculatory dysfunction in patients with Takotsubo cardiomyopathy by myocardial contrast echocardiography.
Clinical cardiology Sep, 2013 | Pubmed ID: 23797947
Proteomic mechanisms of cardioprotection during mammalian hibernation in woodchucks, Marmota monax.
Journal of proteome research Sep, 2013 | Pubmed ID: 23855383
A case of nitinol allergy causing pericardial tamponade.
The Journal of invasive cardiology Sep, 2013 | Pubmed ID: 23995727
Meclizine inhibits mitochondrial respiration through direct targeting of cytosolic phosphoethanolamine metabolism.
The Journal of biological chemistry Dec, 2013 | Pubmed ID: 24142790
Identification of Bax-interacting proteins in oligodendrocyte progenitors during glutamate excitotoxicity and perinatal hypoxia-ischemia.
ASN neuro Dec, 2013 | Pubmed ID: 24195677
Blocking eIF5A modification in cervical cancer cells alters the expression of cancer-related genes and suppresses cell proliferation.
Cancer research Jan, 2014 | Pubmed ID: 24220243
Outcomes of therapeutic penetrating keratoplasty from a tertiary eye care centre in northern India.
Cornea Feb, 2014 | Pubmed ID: 24322798
Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer.
Nature communications , 2014 | Pubmed ID: 24451681
Interconnected network motifs control podocyte morphology and kidney function.
Science signaling Feb, 2014 | Pubmed ID: 24497609
A systematic survey of lipids across mouse tissues.
American journal of physiology. Endocrinology and metabolism Apr, 2014 | Pubmed ID: 24518676
An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Nature genetics Apr, 2014 | Pubmed ID: 24584072
Burden of disease in patients with Morquio A syndrome: results from an international patient-reported outcomes survey.
Orphanet journal of rare diseases Mar, 2014 | Pubmed ID: 24602160
Host biomarkers of invasive pulmonary aspergillosis to monitor therapeutic response.
Antimicrobial agents and chemotherapy Jun, 2014 | Pubmed ID: 24687510
Mst1 promotes cardiac myocyte apoptosis through phosphorylation and inhibition of Bcl-xL.
Molecular cell May, 2014 | Pubmed ID: 24813943
Lipid-lowering therapies, glucose control and incident diabetes: evidence, mechanisms and clinical implications.
Cardiovascular drugs and therapy Aug, 2014 | Pubmed ID: 24952127
Identification of novel nuclear targets of human thioredoxin 1.
Molecular & cellular proteomics : MCP Dec, 2014 | Pubmed ID: 25231459
MicroRNA-7 protects against 1-methyl-4-phenylpyridinium-induced cell death by targeting RelA.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2014 | Pubmed ID: 25232110
A systematic review of the prevalence of Morquio A syndrome: challenges for study reporting in rare diseases.
Orphanet journal of rare diseases Nov, 2014 | Pubmed ID: 25404155
A novel formulation of veggies with potent anti-migraine activity.
International journal of computational biology and drug design , 2015 | Pubmed ID: 25869319
A novel formulation of veggies with potent liver detoxifying activity.
International journal of computational biology and drug design , 2015 | Pubmed ID: 25869321
The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition.
Cell reports Jul, 2015 | Pubmed ID: 26119731
Arteriovenous Blood Metabolomics: A Readout of Intra-Tissue Metabostasis.
Scientific reports Aug, 2015 | Pubmed ID: 26244428
Master redox regulator Trx1 upregulates SMYD1 & modulates lysine methylation.
Biochimica et biophysica acta Dec, 2015 | Pubmed ID: 26410624
MicroRNA-7 activates Nrf2 pathway by targeting Keap1 expression.
Free radical biology & medicine Dec, 2015 | Pubmed ID: 26453926
The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation.
Scientific reports Oct, 2015 | Pubmed ID: 26461067
Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathy.
The Journal of cell biology Nov, 2015 | Pubmed ID: 26598616
Mapping Soluble Guanylyl Cyclase and Protein Disulfide Isomerase Regions of Interaction.
PloS one , 2015 | Pubmed ID: 26618351
Metabolite Profiling and Stable Isotope Tracing in Sorted Subpopulations of Mammalian Cells.
Analytical chemistry Mar, 2016 | Pubmed ID: 26855138
Identification of novel S-nitrosation sites in soluble guanylyl cyclase, the nitric oxide receptor.
Journal of proteomics Apr, 2016 | Pubmed ID: 26917471
Simultaneous tracing of carbon and nitrogen isotopes in human cells.
Molecular bioSystems May, 2016 | Pubmed ID: 27098229
Viewing Extrinsic Proteotoxic Stress Through the Lens of Amyloid Cardiomyopathy.
Physiology (Bethesda, Md.) Jul, 2016 | Pubmed ID: 27252164
Pyridylphosphinate metal complexes: synthesis, structural characterisation and biological activity.
Dalton transactions (Cambridge, England : 2003) Aug, 2016 | Pubmed ID: 27468432
Ethanol-based proliposome delivery systems of paclitaxel for in vitro application against brain cancer cells.
Journal of liposome research Dec, 2016 | Pubmed ID: 27834116
Identification, synthesis and structural characterization of process related and degradation impurities of acrivastine and validation of HPLC method.
Journal of pharmaceutical and biomedical analysis Oct, 2016 | Pubmed ID: 27969063
Determination of five potential genotoxic impurities in dalfampridine using liquid chromatography.
Journal of pharmaceutical and biomedical analysis Oct, 2016 | Pubmed ID: 27969064
Nectin-like 4 complexes with Choline Transporter-Like protein-1, and regulates Schwann cell choline homeostasis and lipid biogenesis in vitro.
The Journal of biological chemistry Jan, 2017 | Pubmed ID: 28119456
Irena Roci1,2,
Hector Gallart-Ayala3,
Jeramie Watrous4,
Mohit Jain4,
Craig E. Wheelock3,
Roland Nilsson1,2
1Department of Medicine, Unit of Computational Medicine, Karolinska Institutet,
2Center for Molecular Medicine, Karolinska Institutet,
3Department of Medical Biochemistry and Biophysics, Division of Physiological Chemistry 2, Karolinska Institutet,
4Department of Medicine, University of California San Diego