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Chemical Biology Section,
Department of Chemistry,
Chemical Biology Section, Department of Chemistry
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A fluorescence-based assay for N-myristoyltransferase activity.
Analytical biochemistry Feb, 2012 | Pubmed ID: 22051857
Multifunctional protein labeling via enzymatic N-terminal tagging and elaboration by click chemistry.
Nature protocols Jan, 2012 | Pubmed ID: 22193303
Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation.
Journal of biophotonics May, 2013 | Pubmed ID: 23184449
Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.
Nature communications Sep, 2014 | Pubmed ID: 25255805
Global profiling of protein lipidation using chemical proteomic technologies.
Current opinion in chemical biology Feb, 2015 | Pubmed ID: 25461723
Isosteric substitutions of urea to thiourea and selenourea in aliphatic oligourea foldamers: site-specific perturbation of the helix geometry.
Chemistry (Weinheim an der Bergstrasse, Germany) Feb, 2015 | Pubmed ID: 25529793
Chemical reporters for exploring protein acylation.
Biochemical Society transactions Apr, 2015 | Pubmed ID: 25849926
Click chemistry armed enzyme-linked immunosorbent assay to measure palmitoylation by hedgehog acyltransferase.
Analytical biochemistry Dec, 2015 | Pubmed ID: 26334609
Proteomic analysis of fatty-acylated proteins.
Current opinion in chemical biology Feb, 2016 | Pubmed ID: 26656971
Mass-tag labeling reveals site-specific and endogenous levels of protein S-fatty acylation.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2016 | Pubmed ID: 27044110
Synthesis and characterisation of 5-acyl-6,7-dihydrothieno[3,2-c]pyridine inhibitors of Hedgehog acyltransferase.
Data in brief Jun, 2016 | Pubmed ID: 27077078
N-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells.
ACS chemical biology Aug, 2016 | Pubmed ID: 27267252
Bioorthogonal Chemical Reporters for Monitoring Unsaturated Fatty-Acylated Proteins.
Chembiochem : a European journal of chemical biology Oct, 2016 | Pubmed ID: 27350074
Imperial College London
Frederik Görlitz*,1,
Douglas J. Kelly*,1,
Sean C. Warren1,
Dominic Alibhai2,
Lucien West3,
Sunil Kumar1,
Yuriy Alexandrov1,
Ian Munro1,
Edwin Garcia1,
James McGinty1,
Clifford Talbot1,
Remigiusz A. Serwa4,
Emmanuelle Thinon4,
Vincenzo da Paola3,
Edward J. Murray5,
Frank Stuhmeier6,
Mark A. A. Neil1,
Edward W. Tate4,
Christopher Dunsby1,7,
Paul M. W. French1
1Photonics Group, Department of Physics, Imperial College London,
2Institute for Chemical Biology, Department of Chemistry, Imperial College London,
3MRC Clinical Sciences Centre, Hammersmith Hospital,
4Chemical Biology Section, Department of Chemistry, Imperial College London,
5, Retroscreen Virology Ltd,
6Pfizer Global Research and Development, Pfizer Limited, Sandwich, Kent, UK,
7Centre for Histopathology, Imperial College London
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