S'identifier

Michelle Monje

Departments of Neurology,
Neurosurgery,
Pathology and Pediatrics,
Institute for Stem Cell Biology and Regenerative Medicine,
Departments of Neurology, Neurosurgery, Pathology and Pediatrics, Institute for Stem Cell Biology and Regenerative Medicine

Stanford University School of Medicine

BIOGRAPHY

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PUBLICATIONS

Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain.

Science (New York, N.Y.) May, 2014 | Pubmed ID: 24727982

Human pontine glioma cells can induce murine tumors.

Acta neuropathologica , 2014 | Pubmed ID: 24777482

Irradiation induces neural precursor-cell dysfunction.

Nature medicine Sep, 2002 | Pubmed ID: 12161748

Radiation injury and neurogenesis.

Current opinion in neurology Apr, 2003 | Pubmed ID: 12644738

Extreme sensitivity of adult neurogenesis to low doses of X-irradiation.

Cancer research Jul, 2003 | Pubmed ID: 12874001

Inflammatory blockade restores adult hippocampal neurogenesis.

Science (New York, N.Y.) Dec, 2003 | Pubmed ID: 14615545

Excitation-neurogenesis coupling in adult neural stem/progenitor cells.

Neuron May, 2004 | Pubmed ID: 15157417

Durable response of a radiation-induced, high-grade cerebellar glioma to temozolomide.

Journal of neuro-oncology Sep, 2007 | Pubmed ID: 17332945

Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies.

Annals of neurology Nov, 2007 | Pubmed ID: 17786983

Cranial radiation therapy and damage to hippocampal neurogenesis.

Developmental disabilities research reviews , 2008 | Pubmed ID: 18924155

Clinical patterns and biological correlates of cognitive dysfunction associated with cancer therapy.

The oncologist Dec, 2008 | Pubmed ID: 19019972

Neurological complications in adults.

Cancer treatment and research , 2009 | Pubmed ID: 19834665

Hedgehogs, flies, Wnts and MYCs: the time has come for many things in medulloblastoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology Apr, 2011 | Pubmed ID: 21357776

Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma.

Proceedings of the National Academy of Sciences of the United States of America Mar, 2011 | Pubmed ID: 21368213

Cognitive side effects of cancer therapy demonstrate a functional role for adult neurogenesis.

Behavioural brain research Feb, 2012 | Pubmed ID: 21621557

Neurological complications following treatment of children with brain tumors.

Journal of pediatric rehabilitation medicine , 2011 | Pubmed ID: 21757808

Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas.

Journal of neuro-oncology Jul, 2012 | Pubmed ID: 22382786

Functional and structural differences in the hippocampus associated with memory deficits in adult survivors of acute lymphoblastic leukemia.

Pediatric blood & cancer Feb, 2013 | Pubmed ID: 22887801

Complete ocular paresis in a child with posterior fossa syndrome.

Pediatric neurosurgery , 2012 | Pubmed ID: 22906880

Effect of cancer therapy on neural stem cells: implications for cognitive function.

Current opinion in oncology Nov, 2012 | Pubmed ID: 22913969

Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas.

Cancer cell Nov, 2013 | Pubmed ID: 24183680

Diffusion-weighted MRI derived apparent diffusion coefficient identifies prognostically distinct subgroups of pediatric diffuse intrinsic pontine glioma.

Journal of neuro-oncology Mar, 2014 | Pubmed ID: 24522717

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma.

Nature genetics May, 2014 | Pubmed ID: 24705252

Subventricular spread of diffuse intrinsic pontine glioma.

Acta neuropathologica Oct, 2014 | Pubmed ID: 24929912

Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.

Nature medicine Jul, 2014 | Pubmed ID: 24973920

Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion.

Cell May, 2015 | Pubmed ID: 25913192

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.

Nature medicine Jun, 2015 | Pubmed ID: 25939062

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.

Nature medicine Jul, 2015 | Pubmed ID: 26151328

Myelin plasticity in the central nervous system.

Neuropharmacology Nov, 2016 | Pubmed ID: 26282119

Diffuse Intrinsic Pontine Glioma: New Pathophysiological Insights and Emerging Therapeutic Targets.

Current neuropharmacology , 2017 | Pubmed ID: 27157264

Pediatric high-grade glioma: biologically and clinically in need of new thinking.

Neuro-oncology Jun, 2016 | Pubmed ID: 27282398

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma.

Nature Nov, 2016 | Pubmed ID: 27806376

Settling a Nervous Stomach: The Neural Regulation of Enteric Cancer.

Cancer cell Jan, 2017 | Pubmed ID: 28073000

The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease.

Journal of neuro-oncology Jan, 2017 | Pubmed ID: 28093680

Brain Perfusion and Diffusion Abnormalities in Children Treated for Posterior Fossa Brain Tumors.

The Journal of pediatrics Feb, 2017 | Pubmed ID: 28187964

INSTITUTIONS

Stanford University School of Medicine

JOVE ARTICLES

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG)

Grant L. Lin¹,

Michelle Monje²

¹Graduate Program in Neuroscience, Department of Neurology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine,

²Departments of Neurology, Neurosurgery, Pathology and Pediatrics, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine

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