Sunil Krishnan

Antitumor effects of cyclin dependent kinase 9 inhibition in esophageal adenocarcinoma.

Combination of epidermal growth factor receptor targeted therapy with radiation therapy for malignant gliomas.

Genetic and signaling pathway alterations in glioblastoma: relevance to novel targeted therapies.

Choroid plexus papillomas: a single institutional experience.

Phase II trial of carmustine, cisplatin, and oral etoposide chemotherapy before radiotherapy for grade 3 astrocytoma (anaplastic astrocytoma): results of North Central Cancer Treatment Group trial 98-72-51.

Radiosurgery for cranial base chordomas and chondrosarcomas.

Intraoperative radiotherapy using a mobile electron LINAC: a retroperitoneal sarcoma case.

The optimization of dose delivery for intraoperative high-dose-rate radiation therapy using curved HAM applicators.

Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: results of North Central Cancer Treatment Group protocol N0177.

Clinical and pathologic predictors of locoregional recurrence, distant metastasis, and overall survival in patients treated with chemoradiation and mesorectal excision for rectal cancer.

Adjuvant therapy for ampullary carcinomas: the Mayo Clinic experience.

Phase II study of capecitabine (Xeloda) and concomitant boost radiotherapy in patients with locally advanced rectal cancer.

Preoperative chemoradiotherapy with capecitabine versus protracted infusion 5-fluorouracil for rectal cancer: a matched-pair analysis.

Concurrent capecitabine and upper abdominal radiation therapy is well tolerated.

Prognostic factors in patients with unresectable locally advanced pancreatic adenocarcinoma treated with chemoradiation.

Conformal radiotherapy of the dominant liver metastasis: a viable strategy for treatment of unresectable chemotherapy refractory colorectal cancer liver metastases.

Correlation between internal fiducial tumor motion and external marker motion for liver tumors imaged with 4D-CT.

Predictors and patterns of recurrence after definitive chemoradiation for anal cancer.

Predictors of tumor response and downstaging in patients who receive preoperative chemoradiation for rectal cancer.

Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products.

Gastrointestinal complications associated with hepatic arterial Yttrium-90 microsphere therapy.

Induction chemotherapy selects patients with locally advanced, unresectable pancreatic cancer for optimal benefit from consolidative chemoradiation therapy.

Targeting cell signaling pathways for drug discovery: an old lock needs a new key.

Clinical benefit of palliative radiation therapy in advanced gastric cancer.

Back to basics: how natural products can provide the basis for new therapeutics.

Role of adjuvant chemoradiation therapy in adenocarcinomas of the ampulla of vater.

Hepatic yttrium-90 radioembolotherapy in metastatic colorectal cancer treated with cetuximab or bevacizumab.

Incidence, natural history, and patterns of locoregional recurrence in gastric cancer patients treated with preoperative chemoradiotherapy.

4D-CT imaging with synchronized intravenous contrast injection to improve delineation of liver tumors for treatment planning.

Daily targeting of liver tumors: screening patients with a mock treatment and using a combination of internal and external fiducials for image-guided respiratory-gated radiotherapy.

Patterns of locoregional recurrence after surgery and radiotherapy or chemoradiation for rectal cancer.

Radiotherapy for hepatocellular carcinoma: an overview.

Imaging epidermal growth factor receptor expression in vivo: pharmacokinetic and biodistribution characterization of a bioconjugated quantum dot nanoprobe.

Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products.

Chemoradiation therapy for potentially resectable gastric cancer: clinical outcomes among patients who do not undergo planned surgery.

Modulation of in vivo tumor radiation response via gold nanoshell-mediated vascular-focused hyperthermia: characterizing an integrated antihypoxic and localized vascular disrupting targeting strategy.

Therapeutic significance of elevated tissue transglutaminase expression in pancreatic cancer.

Effect of combining anti-epidermal growth factor receptor antibody C225 and radiation on DU145 prostate cancer.

Preoperative gemcitabine and cisplatin followed by gemcitabine-based chemoradiation for resectable adenocarcinoma of the pancreatic head.

Does neoadjuvant treatment for gastric cancer patients with positive peritoneal cytology at staging laparoscopy improve survival?

Retrospective study of clinicopathologic features and prognosis of high-grade neuroendocrine carcinoma of the esophagus.

Neutrophil gelatinase-associated lipocalin: a novel suppressor of invasion and angiogenesis in pancreatic cancer.

Improving soft-tissue contrast in four-dimensional computed tomography images of liver cancer patients using a deformable image registration method.

Extrahepatic bile duct adenocarcinoma: patients at high-risk for local recurrence treated with surgery and adjuvant chemoradiation have an equivalent overall survival to patients with standard-risk treated with surgery alone.

Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells.

Phase I/II trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North Central Cancer Treatment Group Study N0177.

Proton radiotherapy for liver tumors: dosimetric advantages over photon plans.

Attempted salvage resection for recurrent gastric or gastroesophageal cancer.

Sacral insufficiency fractures after preoperative chemoradiation for rectal cancer: incidence, risk factors, and clinical course.

Frequent loss of heterozygosity of chromosome 1q in esophageal adenocarcinoma: loss of chromosome 1q21.3 is associated with shorter overall survival.

Long-term survival after multidisciplinary management of resected pancreatic adenocarcinoma.

Temporal patterns of fatigue predict pathologic response in patients treated with preoperative chemoradiation therapy for rectal cancer.

Intensity-modulated radiation therapy for the treatment of squamous cell anal cancer with para-aortic nodal involvement.

Capecitabine and timing of radiotherapy during preoperative chemoradiation for rectal cancer.

The role of adjuvant radiation therapy in nonmetastatic gastric cancer: an evolving paradigm.

Near-infrared narrow-band imaging of gold/silica nanoshells in tumors.

Respiratory gating with EPID-based verification: the MDACC experience.

Spatial distribution, kinetics, signaling and cytokine production during homeostasis driven proliferation of CD4+ T cells.

Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer.

Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model.

The dosimetric feasibility of gold nanoparticle-aided radiation therapy (GNRT) via brachytherapy using low-energy gamma-/x-ray sources.

Hyperfractionated accelerated radiotherapy for rectal cancer in patients with prior pelvic irradiation.

Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity.

Local excision after preoperative chemoradiation results in an equivalent outcome to total mesorectal excision in selected patients with T3 rectal cancer.

Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer.

Reirradiation to the abdomen for gastrointestinal malignancies.

Modeling of plasmonic heating from individual gold nanoshells for near-infrared laser-induced thermal therapy.

Long-term quality of life after radiotherapy for the treatment of anal cancer.

Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway.

A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo.

Sesamin manifests chemopreventive effects through the suppression of NF-kappa B-regulated cell survival, proliferation, invasion, and angiogenic gene products.

Inhibition of radiation-induced DNA repair and prosurvival pathways contributes to vorinostat-mediated radiosensitization of pancreatic cancer cells.

Long-term survival and recurrence outcomes following surgery for distal rectal cancer.

Plumbagin inhibits proliferative and inflammatory responses of T cells independent of ROS generation but by modulating intracellular thiols.

Gadolinium chloride augments tumor-specific imaging of targeted quantum dots in vivo.

Nonoperative therapies for combined modality treatment of hepatocellular cancer: expert consensus statement.

Targeting inflammatory pathways for tumor radiosensitization.

Differential activation of NF-κB and nitric oxide in lymphocytes regulates in vitro and in vivo radiosensitivity.

Estimation of microscopic dose enhancement factor around gold nanoparticles by Monte Carlo calculations.

Nanoparticle-mediated thermal therapy: evolving strategies for prostate cancer therapy.

{Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment.

Effective Dose from Stray Radiation for a Patient Receiving Proton Therapy for Liver Cancer.

Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy.

Methodology for determining doses to in-field, out-of-field and partially in-field organs for late effects studies in photon radiotherapy.

Risk of second malignant neoplasm following proton versus intensity-modulated photon radiotherapies for hepatocellular carcinoma.

Number of lymph nodes examined and prognosis among pathologically lymph node-negative patients after preoperative chemoradiation therapy for rectal adenocarcinoma.

HIF-1-dependent stromal adaptation to ischemia mediates in vivo tumor radiation resistance.

Intra-organ Biodistribution of Gold Nanoparticles Using Intrinsic Two-photon Induced Photoluminescence.

Integrin αvβ3-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy.

Role of definitive radiation therapy in carcinoma of unknown primary in the abdomen and pelvis.

Intensity modulated radiation therapy (IMRT): differences in target volumes and improvement in clinically relevant doses to small bowel in rectal carcinoma.

Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers.

Phase II trial of cetuximab, gemcitabine, and oxaliplatin followed by chemoradiation with cetuximab for locally advanced (T4) pancreatic adenocarcinoma: correlation of Smad4(Dpc4) immunostaining with pattern of disease progression.

Radiation treatment outcomes for unresectable hepatocellular carcinoma.

Decreasing the adverse effects of cancer therapy: an NCI Workshop on the preclinical development of radiation injury mitigators/protectors.

Clinical and prognostic implications of plasma insulin-like growth factor-1 and vascular endothelial growth factor in patients with hepatocellular carcinoma.

Zyflamend suppresses growth and sensitizes human pancreatic tumors to gemcitabine in an orthotopic mouse model through modulation of multiple targets.

Charged-particle therapy for hepatocellular carcinoma.

Intensity-modulated radiation therapy with concurrent chemotherapy as preoperative treatment for localized gastric adenocarcinoma.

Serum sTNF-R1, IL-6, and the development of fatigue in patients with gastrointestinal cancer undergoing chemoradiation therapy.

Narrow band imaging of squamous cell carcinoma tumors using topically delivered anti-EGFR antibody conjugated gold nanorods.

In vivo tumor targeting of gold nanoparticles: effect of particle type and dosing strategy.

A mouse model for triple-negative breast cancer tumor-initiating cells (TNBC-TICs) exhibits similar aggressive phenotype to the human disease.

Neoadjuvant treatment response as an early response indicator for patients with rectal cancer.

Nanoparticle-mediated hyperthermia in cancer therapy.

Development and validation of a sensitive LC/MS/MS method for the determination of γ-tocotrienol in rat plasma: application to pharmacokinetic studies.

Localized gastric cancer treated with chemoradation without surgery: UTMD Anderson Cancer Center experience.

Predicting, preventing, treating and understanding radiation nephropathy.

Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.

Reproducibility and genital sparing with a vaginal dilator used for female anal cancer patients.

Recurrent invasive lobular carcinoma presenting as a ruptured breast implant.

Duodenal toxicity after fractionated chemoradiation for unresectable pancreatic cancer.

Extubation after anaesthesia: a randomised comparison of three techniques.

Intensity-modulated radiation therapy with concurrent chemotherapy for anal cancer: outcomes and toxicity.

Opportunities and challenges in the era of molecularly targeted agents and radiation therapy.

Prevention and Treatment of Colorectal Cancer by Natural Agents From Mother Nature.

KRAS mutations and rectal cancer response to chemoradiation: are we closer to personalization of therapy?

Serum carbohydrate antigen 19-9 represents a marker of response to neoadjuvant therapy in patients with borderline resectable pancreatic cancer.

Targeting pancreatic cancer with magneto-fluorescent theranostic gold nanoshells.

Quantified pathologic response assessed as residual tumor burden is a predictor of recurrence-free survival in patients with rectal cancer who undergo resection after neoadjuvant chemoradiotherapy.

Metformin use and improved response to therapy in rectal cancer.

Combined hyperthermia and radiotherapy for the treatment of cancer.

Intensifying local radiotherapy for pancreatic cancer-who benefits and how do we select them?

Preoperative radiation therapy with concurrent capecitabine, bevacizumab, and erlotinib for rectal cancer: a phase 1 trial.

Intraoperative radiation therapy for locally advanced primary and recurrent colorectal cancer: ten-year institutional experience.

Gold nanoparticles in breast cancer treatment: promise and potential pitfalls.

Comparative analysis of volumetric modulated arc therapy versus intensity modulated radiation therapy for radiotherapy of anal carcinoma.

Gastric bleeding after radiation therapy for intrahepatic cholangiocarcinoma.

Development and validation of insulin-like growth factor-1 score to assess hepatic reserve in hepatocellular carcinoma.

Interobserver variability in target definition for hepatocellular carcinoma with and without portal vein thrombus: radiation therapy oncology group consensus guidelines.

Combining radiation and immunotherapy: a new systemic therapy for solid tumors?

Definitive Chemoradiation for Squamous Cell Carcinoma of the Rectum.

The rare cancer network: ongoing studies and future strategy.

Convergence of nanotechnology with radiation therapy-insights and implications for clinical translation.

Design of an Yb-169 source optimized for gold nanoparticle-aided radiation therapy.

Zerumbone increases oxidative stress in a thiol-dependent ROS-independent manner to increase DNA damage and sensitize colorectal cancer cells to radiation.

Paraneoplastic thrombocytosis independently predicts poor prognosis in patients with locally advanced pancreatic cancer.

Targeted gold nanoparticles enhance sensitization of prostate tumors to megavoltage radiation therapy in vivo.

Minibeam therapy with protons and light ions: physical feasibility and potential to reduce radiation side effects and to facilitate hypofractionation.

HER2/neu-directed therapy for biliary tract cancer.

Radiotherapy-Induced Malfunction in Contemporary Cardiovascular Implantable Electronic Devices: Clinical Incidence and Predictors.

Chemoradiation for High-grade Neuroendocrine Carcinoma of the Rectum and Anal Canal.

Vitamin E Analogs as Radiation Response Modifiers.

Technology for Innovation in Radiation Oncology.

Ablative Radiotherapy Doses Lead to a Substantial Prolongation of Survival in Patients With Inoperable Intrahepatic Cholangiocarcinoma: A Retrospective Dose Response Analysis.

PDL1 Regulation by p53 via miR-34.

In Reply to Sahadevan.

Charged Particle Therapy with Mini-Segmented Beams.

Roadmap to Clinical Use of Gold Nanoparticles for Radiation Sensitization.

Hyperthermia using nanoparticles--Promises and pitfalls.

The evolving evidence for the efficacy and safety of charged particle therapy for hepatocellular carcinoma-a commentary.

Quantitative imaging of gold nanoparticle distribution in a tumor-bearing mouse using benchtop x-ray fluorescence computed tomography.

Everything Old Is New Again: Using Nelfinavir to Radiosensitize Rectal Cancer.

Immunotherapy and stereotactic ablative radiotherapy (ISABR): a curative approach?

Quantitative investigation of physical factors contributing to gold nanoparticle-mediated proton dose enhancement.

Focal Radiation Therapy Dose Escalation Improves Overall Survival in Locally Advanced Pancreatic Cancer Patients Receiving Induction Chemotherapy and Consolidative Chemoradiation.

Corrigendum to "Targeted gold nanoparticles enhance sensitization of prostate tumors to megavoltage radiation therapy in vivo" [Nanomedicine: Nanotechnology, Biology, and Medicine 11 (2015) 1277-1283].

Oncologic and Functional Hazards of Obesity Among Patients With Locally Advanced Rectal Cancer Following Neoadjuvant Chemoradiation Therapy.

Tumor Cells Surviving Exposure to Proton or Photon Radiation Share a Common Immunogenic Modulation Signature, Rendering Them More Sensitive to T Cell-Mediated Killing.

Pharmacokinetic, biodistribution and therapeutic efficacy of 5-fluorouracil-loaded pH-sensitive PEGylated liposomal nanoparticles in HCT-116 tumor bearing mouse.

Impact of hypofractionated and standard fractionated chemoradiation before pancreatoduodenectomy for pancreatic ductal adenocarcinoma.

Phase I Trial of Consolidative Radiotherapy with Concurrent Bevacizumab, Erlotinib and Capecitabine for Unresectable Pancreatic Cancer.

Radiotherapy for Hepatocellular Carcinoma: New Indications and Directions for Future Study.

DNA Mismatch Repair Deficiency in Rectal Cancer: Benchmarking Its Impact on Prognosis, Neoadjuvant Response Prediction, and Clinical Cancer Genetics.

Current Insights in Radiation Combination Therapies: Influence of Omics and Novel Targeted Agents in Defining New Concepts in Radiation Biology and Clinical Radiation Oncology.

Recent Advances and Prospects for Multimodality Therapy in Pancreatic Cancer.

Biliary cancer: Utility of next-generation sequencing for clinical management.

Preoperative Chemoradiation for Pancreatic Adenocarcinoma Does Not Increase 90-Day Postoperative Morbidity or Mortality.

Hyperfractionated Accelerated Reirradiation for Patients With Recurrent Anal Cancer Previously Treated With Definitive Chemoradiation.

Preoperative Therapy and Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: a 25-Year Single-Institution Experience.

H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer.

Suppression of Type I IFN Signaling in Tumors Mediates Resistance to Anti-PD-1 Treatment That Can Be Overcome by Radiotherapy.

Hyperfractionated accelerated reirradiation for rectal cancer: An analysis of outcomes and toxicity.

Does Unintentional Splenic Radiation Predict Outcomes After Pancreatic Cancer Radiation Therapy?

Reduced expression of argininosuccinate synthetase 1 has a negative prognostic impact in patients with pancreatic ductal adenocarcinoma.

Mitochondrion-Anchoring Photosensitizer with Aggregation-Induced Emission Characteristics Synergistically Boosts the Radiosensitivity of Cancer Cells to Ionizing Radiation.

Real-time liver uptake and biodistribution of magnetic nanoparticles determined by AC biosusceptometry.

The Rise of Radiomics and Implications for Oncologic Management.

In Reply to Yazici et al.