Claire Usal

Extrarenal effects on the pathogenesis and relapse of idiopathic nephrotic syndrome in Buffalo/Mna rats.

Role for thymic and splenic regulatory CD4+ T cells induced by donor dendritic cells in allograft tolerance by LF15-0195 treatment.

Induction of donor-specific allograft tolerance by short-term treatment with LF15-0195 after transplantation. Evidence for a direct effect on T-cell differentiation.

Presentation of donor major histocompatibility complex antigens by bone marrow dendritic cell-derived exosomes modulates allograft rejection.

The effect of a first kidney transplant on a subsequent transplant outcome: an experimental and clinical study.

Inhibition of chronic rejection and development of tolerogenic T cells after ICOS-ICOSL and CD40-CD40L co-stimulation blockade.

Exhaustive depletion of graft resident dendritic cells: marginally delayed rejection but strong alteration of graft infiltration.

Anti-CD28 antibody-induced kidney allograft tolerance related to tryptophan degradation and TCR class II B7 regulatory cells.

Inhibition of chronic rejection and development of tolerogenic T cells after ICOS-ICOSL and CD40-CD40L co-stimulation blockade.

Renal macrophage activation and Th2 polarization precedes the development of nephrotic syndrome in Buffalo/Mna rats.

Transgenic modifications of the rat genome.

Dominant tolerance to kidney allografts induced by anti-donor MHC class II antibodies: cooperation between T and non-T CD103+ cells.

CD40Ig treatment results in allograft acceptance mediated by CD8CD45RC T cells, IFN-gamma, and indoleamine 2,3-dioxygenase.

Nitric oxide and indoleamine 2,3-dioxygenase mediate CTLA4Ig-induced survival in heart allografts in rats.

Anti-CD28 antibodies modify regulatory mechanisms and reinforce tolerance in CD40Ig-treated heart allograft recipients.

Depletion of LAG-3 positive cells in cardiac allograft reveals their role in rejection and tolerance.

Implication of matrix metalloproteinase 7 and the noncanonical wingless-type signaling pathway in a model of kidney allograft tolerance induced by the administration of anti-donor class II antibodies.

Myeloid-derived suppressor cells accumulate in kidney allograft tolerance and specifically suppress effector T cell expansion.

Induction of T regulatory cells attenuates idiopathic nephrotic syndrome.

Autoimmune responses against renal tissue proteins in long-term surviving allograft recipients.

Zinc-finger nucleases: a powerful tool for genetic engineering of animals.

"Transgenesis, recent technical developments and applications" Nantes, 8th June 2009.

Generation of transgenic rats by microinjection of short DNA fragments.

The use of lentiviral vectors to obtain transgenic rats.

Generation of gene-specific mutated rats using zinc-finger nucleases.

Analysis by quantitative PCR of zygosity in genetically modified organisms.

Immunoproteasome beta subunit 10 is increased in chronic antibody-mediated rejection.

Mechanism and localization of CD8 regulatory T cells in a heart transplant model of tolerance.

Lentiviral vectors that express UGT1A1 in liver and contain miR-142 target sequences normalize hyperbilirubinemia in Gunn rats.

Development of initial idiopathic nephrotic syndrome and post-transplantation recurrence: evidence of the same biological entity.

Characterization of immunoglobulin heavy chain knockout rats.

TNF blockade abrogates the induction of T cell-dependent humoral responses in an allotransplantation model.

Effects of Human Alpha-Synuclein A53T-A30P Mutations on SVZ and Local Olfactory Bulb Cell Proliferation in a Transgenic Rat Model of Parkinson Disease.

Knockout rats generated by embryo microinjection of TALENs.

Effects of BCL-2 over-expression on B cells in transgenic rats and rat hybridomas.

Control of transplant tolerance and intragraft regulatory T cell localization by myeloid-derived suppressor cells and CCL5.

Immunoregulatory function of IL-27 and TGF-β1 in cardiac allograft transplantation.

Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases.

Technical advances in the generation of transgenic animals and in their applications. Nantes, France, June 7th 2013.

Gene targeting in rats using transcription activator-like effector nucleases.

Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases.

Transgenic animals and genetic engineering techniques. Nantes, France, 2-3 July, 2015.

IL-34 is a Treg-specific cytokine and mediates transplant tolerance.

Regulatory B Cells with a Partial Defect in CD40 Signaling and Overexpressing Granzyme B Transfer Allograft Tolerance in Rodents.

Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.

Genome Editing in Rats Using TALE Nucleases.

A Rapid and Cost-Effective Method for Genotyping Genome-Edited Animals: A Heteroduplex Mobility Assay Using Microfluidic Capillary Electrophoresis.

Comparative Analysis of piggyBac, CRISPR/Cas9 and TALEN Mediated BAC Transgenesis in the Zygote for the Generation of Humanized SIRPA Rats.