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Center for Neurosciences of Coimbra,
Institute of Biochemistry,
Faculty of Medicine,
Center for Neurosciences of Coimbra, Institute of Biochemistry, Faculty of Medicine
Paula M. Canas has not added Biography.
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Modification of adenosine modulation of acetylcholine release in the hippocampus of aged rats.
Neurobiology of aging Oct, 2008 | Pubmed ID: 17481781
Blockade of adenosine A(2A) receptors prevents staurosporine-induced apoptosis of rat hippocampal neurons.
Neurobiology of disease Aug, 2007 | Pubmed ID: 17596953
Adenosine A2A receptor blockade prevents memory dysfunction caused by beta-amyloid peptides but not by scopolamine or MK-801.
Experimental neurology Apr, 2008 | Pubmed ID: 18191838
Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms.
Annals of neurology Mar, 2008 | Pubmed ID: 18300283
Modification upon aging of the density of presynaptic modulation systems in the hippocampus.
Neurobiology of aging Nov, 2009 | Pubmed ID: 18304697
A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2008 | Pubmed ID: 18354001
GDNF control of the glutamatergic cortico-striatal pathway requires tonic activation of adenosine A receptors.
Journal of neurochemistry Mar, 2009 | Pubmed ID: 19141075
Spermine improves recognition memory deficit in a rodent model of Huntington's disease.
Neurobiology of learning and memory Nov, 2009 | Pubmed ID: 19632348
Key modulatory role of presynaptic adenosine A2A receptors in cortical neurotransmission to the striatal direct pathway.
TheScientificWorldJournal Nov, 2009 | Pubmed ID: 19936569
Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2009 | Pubmed ID: 19940169
Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction.
Journal of neurochemistry Apr, 2011 | Pubmed ID: 21235574
Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing.
The European journal of neuroscience Jul, 2011 | Pubmed ID: 21615561
Predominant loss of glutamatergic terminal markers in a β-amyloid peptide model of Alzheimer's disease.
Neuropharmacology Jan, 2014 | Pubmed ID: 24029236
Adenosine A₂A receptors in striatal glutamatergic terminals and GABAergic neurons oppositely modulate psychostimulant action and DARPP-32 phosphorylation.
PloS one , 2013 | Pubmed ID: 24312250
The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis.
Neuropharmacology Jun, 2014 | Pubmed ID: 24508709
Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and Anxiety.
Frontiers in psychiatry , 2014 | Pubmed ID: 24982640
Hyperactivation of D1 and A2A receptors contributes to cognitive dysfunction in Huntington's disease.
Neurobiology of disease Feb, 2015 | Pubmed ID: 25449908
Adenosine A2b receptors control A1 receptor-mediated inhibition of synaptic transmission in the mouse hippocampus.
The European journal of neuroscience Apr, 2015 | Pubmed ID: 25704806
The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system.
Journal of neurochemistry Jul, 2015 | Pubmed ID: 25824528
Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2015 | Pubmed ID: 26056314
Depression as a Glial-Based Synaptic Dysfunction.
Frontiers in cellular neuroscience , 2015 | Pubmed ID: 26834566
Presymptomatic MPTP Mice Show Neurotrophic S100B/mRAGE Striatal Levels.
CNS neuroscience & therapeutics May, 2016 | Pubmed ID: 26843141
Age-Related Changes in the Synaptic Density of Amyloid-β Protein Precursor and Secretases in the Human Cerebral Cortex.
Journal of Alzheimer's disease : JAD Apr, 2016 | Pubmed ID: 27104908
University of Coimbra
Xavier Morató*,1,2,
Marc López-Cano*,1,2,
Paula M. Canas3,
Rodrigo A. Cunha3,
Francisco Ciruela1,2
1Unitat de Farmacologia, Departament Patologia i Terapèutica Experimental, Facultat de Medicina, IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat,
2Institut de Neurociències, Universitat de Barcelona,
3Center for Neurosciences of Coimbra, Institute of Biochemistry, Faculty of Medicine, University of Coimbra
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