Atsushi Miyanohara

Cell surface heparan sulfate is a receptor for attachment of envelope protein-free retrovirus-like particles and VSV-G pseudotyped MLV-derived retrovirus vectors to target cells.

Increased smooth muscle cell expression of caveolin-1 and caveolae contribute to the pathophysiology of idiopathic pulmonary arterial hypertension.

Adenylyl cyclase type VI increases Akt activity and phospholamban phosphorylation in cardiac myocytes.

Cardiac-specific overexpression of caveolin-3 induces endogenous cardiac protection by mimicking ischemic preconditioning.

Galphaq reduces cAMP production by decreasing Galphas protein abundance.

Activation of PH-domain leucine-rich protein phosphatase 2 (PHLPP2) by agonist stimulation in cardiac myocytes expressing adenylyl cyclase type 6.

beta(1)-Adrenergic receptor vs adenylyl cyclase 6 expression in cardiac myocytes: differences in transgene localization and intracellular signaling.

Beneficial effects of adenylyl cyclase type 6 (AC6) expression persist using a catalytically inactive AC6 mutant.

Loss of caveolin-1 accelerates neurodegeneration and aging.

Neuron-targeted caveolin-1 protein enhances signaling and promotes arborization of primary neurons.

Volatile anesthetics protect cancer cells against tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via caveolins.

Human oxidation-specific antibodies reduce foam cell formation and atherosclerosis progression.

Improved function of the failing rat heart by regulated expression of insulin-like growth factor I via intramuscular gene transfer.

Combinational spinal GAD65 gene delivery and systemic GABA-mimetic treatment for modulation of spasticity.

Purinergic signaling in human pluripotent stem cells is regulated by the housekeeping gene encoding hypoxanthine guanine phosphoribosyltransferase.

In vivo gene knockdown in rat dorsal root ganglia mediated by self-complementary adeno-associated virus serotype 5 following intrathecal delivery.

Preparation of vesicular stomatitis virus-G (VSV-G) conjugate and its use in gene transfer.

Mitochondria-localized caveolin in adaptation to cellular stress and injury.

Comparison of adeno-associated virus serotypes and delivery methods for cardiac gene transfer.

AAV9-mediated VEGF-B gene transfer improves systolic function in progressive left ventricular hypertrophy.

A kinase interacting protein (AKIP1) is a key regulator of cardiac stress.

Intravenous adeno-associated virus serotype 8 encoding urocortin-2 provides sustained augmentation of left ventricular function in mice.

A transgenic minipig model of Huntington's Disease.

Intravenous AAV8 Encoding Urocortin-2 Increases Function of the Failing Heart in Mice.

Human mutant huntingtin disrupts vocal learning in transgenic songbirds.

Rigid substrate induces esophageal smooth muscle hypertrophy and eosinophilic esophagitis fibrotic gene expression.

Potent spinal parenchymal AAV9-mediated gene delivery by subpial injection in adult rats and pigs.

One-time injection of AAV8 encoding urocortin 2 provides long-term resolution of insulin resistance.

Lung carcinoma progression and survival versus amino- and carboxyl-parathyroid hormone-related protein expression.