Tilman Borggrefe

SWAP-70-deficient mast cells are impaired in development and IgE-mediated degranulation.

A complex of the Srb8, -9, -10, and -11 transcriptional regulatory proteins from yeast.

Association of the Mediator complex with enhancers of active genes.

A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.

The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization.

RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes.

The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220.

ETO, but not leukemogenic fusion protein AML1/ETO, augments RBP-Jkappa/SHARP-mediated repression of notch target genes.

Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex.

Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1.

RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.

Interactions between subunits of the Mediator complex with gene-specific transcription factors.

Essential role of Mediator subunit Med1 in invariant natural killer T-cell development.

Fine-tuning of the intracellular canonical Notch signaling pathway.

RNA helicase Ddx5 and the noncoding RNA SRA act as coactivators in the Notch signaling pathway.

Keeping notch target genes off: a CSL corepressor caught in the act.

The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells.

Probing the epigenetic status at Notch target genes.

Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response.

The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways.

Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination.

A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes.

Setting the Stage for Notch: The Drosophila Su(H)-Hairless Repressor Complex.

Host-derived extracellular RNA promotes adhesion of Streptococcus pneumoniae to endothelial and epithelial cells.

Dynamic chromatin regulation at Notch target genes.