Paul Jardine

Bacteriophage phi 29 DNA packaging.

Mechanism of force generation of a viral DNA packaging motor.

Discovery of highly selective EP4 receptor agonists that stimulate new bone formation and restore bone mass in ovariectomized rats.

Structural changes of bacteriophage phi29 upon DNA packaging and release.

Experimental test of connector rotation during DNA packaging into bacteriophage phi29 capsids.

Ionic effects on viral DNA packaging and portal motor function in bacteriophage phi 29.

Portal motor velocity and internal force resisting viral DNA packaging in bacteriophage phi29.

Three-dimensional architecture of the bacteriophage phi29 packaged genome and elucidation of its packaging process.

Analysis of intermolecular base pair formation of prohead RNA of the phage phi29 DNA packaging motor using NMR spectroscopy.

DNA poised for release in bacteriophage phi29.

Hydrogen/deuterium exchange on protein solutions containing nucleic acids: utility of protamine sulfate.

Role of the CCA bulge of prohead RNA of bacteriophage ø29 in DNA packaging.

Intersubunit coordination in a homomeric ring ATPase.

Substrate interactions and promiscuity in a viral DNA packaging motor.

A new method to detect loss of heterozygosity using cohort heterozygosity comparisons.

Discovery of N-benzyl-2-[(4S)-4-(1H-indol-3-ylmethyl)-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl]-N-isopropylacetamide, an orally active, gut-selective CCK1 receptor agonist for the potential treatment of obesity.

Structure and assembly of the essential RNA ring component of a viral DNA packaging motor.

Role of φ29 connector channel loops in late-stage DNA packaging.

Discovery of new piperidine amide triazolobenzodiazepinones as intestinal-selective CCK1 receptor agonists.

Structure of the RNA claw of the DNA packaging motor of bacteriophage Φ29.

三螺旋交界处是 Prohead RNA 在 29 DNA 包装中的两个功能域之间的接口。

High degree of coordination and division of labor among subunits in a homomeric ring ATPase.

Genome replication, synthesis, and assembly of the bacteriophage T7 in a single cell-free reaction.

Insights into the structure and assembly of the bacteriophage 29 double-stranded DNA packaging motor.

A viral packaging motor varies its DNA rotation and step size to preserve subunit coordination as the capsid fills.

Nonequilibrium dynamics and ultraslow relaxation of confined DNA during viral packaging.

Repulsive DNA-DNA interactions accelerate viral DNA packaging in phage Phi29.

Note to the Paper by Guasch et al. (2002) Detailed Architecture of a DNA Translocating Machine: The High-resolution Structure of the Bacteriophage ϕ29 Connector Particle.

An RNA Domain Imparts Specificity and Selectivity to a Viral DNA Packaging Motor.

Packaging Models versus Modeling Packaging.

Structural and Molecular Basis for Coordination in a Viral DNA Packaging Motor.

Single DNA molecule jamming and history-dependent dynamics during motor-driven viral packaging.

The Interprofessional Collaborative Competency Attainment Survey (ICCAS): A replication validation study.

Experimental comparison of forces resisting viral DNA packaging and driving DNA ejection.