Beth Coyle

Characterization of the transforming growth factor-beta 1-induced apoptotic transcriptome in FaO hepatoma cells.

Early drug safety evaluation: biomarkers, signatures, and fingerprints.

Novel strategy to study gene expression and function in developing cerebellar granule cells.

Regulation of apoptosis by peroxisome proliferators.

Strategies to investigate gene expression and function in granule cells.

Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma.

Pediatric ependymoma: biological perspectives.

Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease.

Cross-species genomics matches driver mutations and cell compartments to model ependymoma.

Histone deacetylase inhibition attenuates cell growth with associated telomerase inhibition in high-grade childhood brain tumor cells.

Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion.

Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas.

Genome-wide molecular characterization of central nervous system primitive neuroectodermal tumor and pineoblastoma.

Pediatric high-grade glioma: identification of poly(ADP-ribose) polymerase as a potential therapeutic target.

RASSF1A and the BH3-only mimetic ABT-737 promote apoptosis in pediatric medulloblastoma cell lines.

Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death.

CD105 (Endoglin) exerts prognostic effects via its role in the microvascular niche of paediatric high grade glioma.

Copy number gain of 1q25 predicts poor progression-free survival for pediatric intracranial ependymomas and enables patient risk stratification: a prospective European clinical trial cohort analysis on behalf of the Children's Cancer Leukaemia Group (CCLG), Societe Francaise d'Oncologie Pediatrique (SFOP), and International Society for Pediatric Oncology (SIOP).

PI3K pathway activation provides a novel therapeutic target for pediatric ependymoma and is an independent marker of progression-free survival.

Overcoming multiple drug resistance mechanisms in medulloblastoma.

ABCB1 in children's brain tumours.

In vitro models of medulloblastoma: Choosing the right tool for the job.

Medulloblastoma and ependymoma cells display increased levels of 5-carboxylcytosine and elevated TET1 expression.