Gertjan J.L. Kaspers

Alpe d'HuZes cancer rehabilitation (A-CaRe) research: four randomized controlled exercise trials and economic evaluations in cancer patients and survivors.

Congenital leukaemia: the Dutch experience and review of the literature.

Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities.

Clinical significance of cellular drug resistance in childhood leukemia.

Past, current and future protocols for combined modality therapy in childhood medulloblastoma.

The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis.

FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance.

Folate concentration dependent transport activity of the Multidrug Resistance Protein 1 (ABCC1).

The effect of G-CSF on the in vitro cytotoxicity of cytarabine and fludarabine in the FLAG combination in pediatric acute myeloid leukemia.

Immunophenotypic cell lineage and in vitro cellular drug resistance in childhood relapsed acute lymphoblastic leukaemia.

Use of the differential staining cytotoxicity assay to predict chemosensitivity.

6th International Symposium and expert workshops on Leukemia and Lymphoma. 17-19 March, 2005, Amsterdam, The Netherlands.

In vitro profiling of the sensitivity of pediatric leukemia cells to tipifarnib: identification of T-cell ALL and FAB M5 AML as the most sensitive subsets.

Treatment of childhood acute myeloid leukemia.

Low efficacy of methotrexate in childhood acute myeloid leukemia (AML): single-agent therapeutic window study in relapsed AML.

In vitro sensitivity and cross-resistance to deoxynucleoside analogs in childhood acute leukemia.

Acquired resistance to chloroquine in human CEM T cells is mediated by multidrug resistance-associated protein 1 and provokes high levels of cross-resistance to glucocorticoids.

Clinical implications of FLT3 mutations in pediatric AML.

A conditionally replicating adenovirus with strict selectivity in killing cells expressing epidermal growth factor receptor.

Sulfasalazine sensitises human monocytic/macrophage cells for glucocorticoids by upregulation of glucocorticoid receptor alpha and glucocorticoid induced apoptosis.

Enhanced tumor cell kill by combined treatment with a small-molecule antagonist of mouse double minute 2 and adenoviruses encoding p53.

Pediatric acute myeloid leukemia: towards high-quality cure of all patients.

Intravenous administration of the conditionally replicative adenovirus Ad5-Delta24RGD induces regression of osteosarcoma lung metastases.

The usefulness of growth hormone treatment for psychological status in young adult survivors of childhood leukaemia: an open-label study.

Role of tyrosine phosphatase inhibitors in cancer treatment with emphasis on SH2 domain-containing tyrosine phosphatases (SHPs).

Old drug, new lessons.

Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study.

Attenuated AMPA receptor expression allows glioblastoma cell survival in glutamate-rich environment.

Folate related gene polymorphisms and susceptibility to develop childhood acute lymphoblastic leukaemia.

FLT3 and KIT mutated pediatric acute myeloid leukemia (AML) samples are sensitive in vitro to the tyrosine kinase inhibitor SU11657.

Strategies for the analysis of in vitro radiation sensitivity and prediction of interaction with potential radiation modifying agents.

Pediatric oncologists' attitudes towards involving adolescents in decision-making concerning research participation.

A review on allogeneic stem cell transplantation for newly diagnosed pediatric acute myeloid leukemia.

High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: implications for personalized medicine.

In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma.

Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia.

Design of the Quality of Life in Motion (QLIM) study: a randomized controlled trial to evaluate the effectiveness and cost-effectiveness of a combined physical exercise and psychosocial training program to improve physical fitness in children with cancer.

Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia.

Fatigue in children: reliability and validity of the Dutch PedsQLâ„¢ Multidimensional Fatigue Scale.

Cystatin C more accurately detects mildly impaired renal function than creatinine in children receiving treatment for malignancy.

Impaired sleep affects quality of life in children during maintenance treatment for acute lymphoblastic leukemia: an exploratory study.

Cell sensitivity assays: the MTT assay.

WEE1 inhibition sensitizes osteosarcoma to radiotherapy.

Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study.

Cost-effectiveness of treatment of childhood acute lymphoblastic leukemia with chemotherapy only: the influence of new medication and diagnostic technology.

Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia.

Blood pressure and body composition in long-term survivors of childhood acute lymphoblastic leukemia.

Using web-based and paper-based questionnaires for collecting data on fertility issues among female childhood cancer survivors: differences in response characteristics.

Effect of corruption on medical care in low-income countries.

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation.

Malignant melanoma as second malignant neoplasm in long-term childhood cancer survivors: a systematic review.

Pediatric acute myeloid leukemia.

Value of routine bone marrow examination in pediatric acute myeloid leukemia (AML): a study of the Dutch Childhood Oncology Group (DCOG).

Hypothalamic-pituitary-adrenal axis function in survivors of childhood acute lymphoblastic leukemia and healthy controls.

Health-related quality of life and utility scores in short-term survivors of pediatric acute lymphoblastic leukemia.

Sleep, fatigue, depression, and quality of life in survivors of childhood acute lymphoblastic leukemia.

A nationwide study on reproductive function, ovarian reserve, and risk of premature menopause in female survivors of childhood cancer: design and methodological challenges.

WEE1 kinase inhibition enhances the radiation response of diffuse intrinsic pontine gliomas.

Improved outcome in pediatric relapsed acute myeloid leukemia: results of a randomized trial on liposomal daunorubicin by the International BFM Study Group.

Cost-analysis of treatment of childhood acute lymphoblastic leukemia with asparaginase preparations: the impact of expensive chemotherapy.

Telomere length and telomerase complex mutations in pediatric acute myeloid leukemia.

Physical exercise training interventions for children and young adults during and after treatment for childhood cancer.

In vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine glioma.

Health status utilities in pediatrics: a systematic review of acute lymphoblastic leukemia.

Diversity in renal function monitoring and dose modifications during treatment for childhood cancer: a call for standardization.

Adequate endocrine and cardiovascular response to social stress in survivors of childhood acute lymphoblastic leukemia.

Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors.

Height-independent estimation of glomerular filtration rate in children: an alternative to the Schwartz equation.

Why pediatricians fail to diagnose hypertension: a multicenter survey.

High resolution SNP array profiling identifies variability in retinoblastoma genome stability.

Childhood lymphomatoid granulomatosis: a report of 2 cases and review of the literature.

Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines.

t(6;9)(p22;q34)/DEK-NUP214-rearranged pediatric myeloid leukemia: an international study of 62 patients.

A prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia.

Pre-B-cell leukemia homeobox interacting protein 1 is overexpressed in astrocytoma and promotes tumor cell growth and migration.

EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma.

Anti-leukemic activity and mechanisms underlying resistance to the novel immunoproteasome inhibitor PR-924.

Antileukemic activity and mechanism of drug resistance to the marine Salinispora tropica proteasome inhibitor salinosporamide A (Marizomib).

Human pontine glioma cells can induce murine tumors.

Identification of temozolomide resistance factors in glioblastoma via integrative miRNA/mRNA regulatory network analysis.

Determinants of quality of life during induction therapy in pediatric acute lymphoblastic leukemia.

Relevance of leukemic stem cells in acute myeloid leukemia: heterogeneity and influence on disease monitoring, prognosis and treatment design.

Convection enhanced delivery of carmustine to the murine brainstem: a feasibility study.

Factors influencing childhood cancer patients to participate in a combined physical and psychosocial intervention program: Quality of Life in Motion.

A twenty-year review of diagnosing and treating children with diffuse intrinsic pontine glioma in The Netherlands.

Pre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance.

Applicability and evaluation of a psychosocial intervention program for childhood cancer patients.

Molecular basis of resistance to proteasome inhibitors in hematological malignancies.

No efficacy for silicone gel sheeting in prevention of abnormal scar formation in children with cancer: a randomized controlled trial.

Gene expression profiles associated with pediatric relapsed AML.

Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia.

Comparing Health-Care Providers' Perspectives on Complementary and Alternative Medicine in Childhood Cancer Between Netherlands and Indonesia.

Hypothalamic-pituitary-adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia.

Palliative and end-of-life care for children with diffuse intrinsic pontine glioma: results from a London cohort study and international survey.

Effects of a combined physical and psychosocial intervention program for childhood cancer patients on quality of life and psychosocial functioning: results of the QLIM randomized clinical trial.

Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance.

Cardiorespiratory fitness and physical activity in children with cancer.

Recurrent translocation t(10;17)(p15;q21) in minimally differentiated acute myeloid leukemia results in ZMYND11/MBTD1 fusion.

miR expression profiling at diagnosis predicts relapse in pediatric precursor B-cell acute lymphoblastic leukemia.

Screening for Psychosocial Risk in Dutch Families of a Child With Cancer: Reliability, Validity, and Usability of the Psychosocial Assessment Tool.

Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis.

A chemical screen for medulloblastoma identifies quercetin as a putative radiosensitizer.

Physical exercise training interventions for children and young adults during and after treatment for childhood cancer.

The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia.

A Meta-Analysis of Retinoblastoma Copy Numbers Refines the List of Possible Driver Genes Involved in Tumor Progression.

Somatic genomic alterations in retinoblastoma beyond RB1 are rare and limited to copy number changes.

State of affairs in use of steroids in diffuse intrinsic pontine glioma: an international survey and a review of the literature.

Bevacizumab Targeting Diffuse Intrinsic Pontine Glioma: Results of 89Zr-Bevacizumab PET Imaging in Brain Tumor Models.

Real-world implementation of electronic patient-reported outcomes in outpatient pediatric cancer care.

Proteasome subunit expression analysis and chemosensitivity in relapsed paediatric acute leukaemia patients receiving bortezomib-containing chemotherapy.

Genomic landscape of retinoblastoma in Rbp130mice resembles human retinoblastoma.

Strategies for reducing the treatment-related physical burden of childhood acute myeloid leukaemia - a review.

An 8-Year-Old Girl with Ocular Swelling.

Chemotherapy-related late adverse effects on ovarian function in female survivors of childhood and young adult cancer: A systematic review.

Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease.

Population pharmacokinetics of intravenous Erwinia asparaginase in pediatric acute lymphoblastic leukemia patients.

Preclinical evaluation of convection-enhanced delivery of liposomal doxorubicin to treat pediatric diffuse intrinsic pontine glioma and thalamic high-grade glioma.

External validation of the diffuse intrinsic pontine glioma survival prediction model: a collaborative report from the International DIPG Registry and the SIOPE DIPG Registry.

A phase I/II study of gemcitabine during radiotherapy in children with newly diagnosed diffuse intrinsic pontine glioma.

A cost analysis of individualized asparaginase treatment in pediatric acute lymphoblastic leukemia.

Multiregional tumor drug-uptake imaging by PET and microvascular morphology in end-stage diffuse intrinsic pontine glioma.

Culture methods of diffuse intrinsic pontine glioma cells determine response to targeted therapies.

Deceptive morphologic and epigenetic heterogeneity in diffuse intrinsic pontine glioma.

Correction to: A phase I/II study of gemcitabine during radiotherapy in children with newly diagnosed diffuse intrinsic pontine glioma.

Leukaemic stem cell load at diagnosis predicts the development of relapse in young acute myeloid leukaemia patients.

Trimethylation of H3K27 during human cerebellar development in relation to medulloblastoma.

Effective Drug Delivery in Diffuse Intrinsic Pontine Glioma: A Theoretical Model to Identify Potential Candidates.

Signaling pathways and mesenchymal transition in pediatric high-grade glioma.

Clinical challenges in de novo pediatric acute myeloid leukemia.