Manfred J. Schmitt

Unique double-stranded RNAs responsible for the anti-Candida activity of the yeast Hanseniaspora uvarum.

The viral killer system in yeast: from molecular biology to application.

Yeast viral killer toxins: lethality and self-protection.

Viral induced yeast apoptosis.

A yeast killer toxin screen provides insights into a/b toxin entry, trafficking, and killing mechanisms.

RNA-directed DNA methylation and plant development require an IWR1-type transcription factor.

Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulum.

Yeast-based protein delivery to mammalian phagocytic cells is increased by coexpression of bacterial listeriolysin.

Uptake of various yeast genera by antigen-presenting cells and influence of subcellular antigen localization on the activation of ovalbumin-specific CD8 T lymphocytes.

Novel yeast bioassay for high-throughput screening of matrix metalloproteinase inhibitors.

Adapting yeast as model to study ricin toxin a uptake and trafficking.

mRNA delivery to human dendritic cells by recombinant yeast and activation of antigen-specific memory T cells.

Heat treatment improves antigen-specific T cell activation after protein delivery by several but not all yeast genera.

Schizosaccharomyces pombe: a novel transport vehicle of functional DNA and mRNA into mammalian antigen-presenting cells.

Surface-modified yeast cells: A novel eukaryotic carrier for oral application.

Cargo binding promotes KDEL receptor clustering at the mammalian cell surface.

H/KDEL receptors mediate host cell intoxication by a viral A/B toxin in yeast.

Yeast Reporter Assay to Identify Cellular Components of Ricin Toxin A Chain Trafficking.

Cysteine residues in a yeast viral A/B toxin crucially control host cell killing via pH-triggered disulfide rearrangements.

Yeast Killer Toxin K28: Biology and Unique Strategy of Host Cell Intoxication and Killing.

Expression of K1 Toxin Derivatives in Saccharomyces cerevisiae Mimics Treatment with Exogenous Toxin and Provides a Useful Tool for Elucidating K1 Mechanisms of Action and Immunity.

Maturation and cytokine pattern of human dendritic cells in response to different yeasts.